Clinical pharmacology profile of an oral selective androgen receptor down-regulator, AZD3514: Implications on the design of ongoing castrate-resistant prostate cancer clinical studies

Inhibition of the Androgen Receptor Amino-Terminal Domain by a Small Molecule as Treatment for Castrate-Resistant Prostate Cancer

10.21236/ada590496 ◽

2013 ◽

Author(s):

Stephen R. Plymate

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Small Molecule ◽

Amino Terminal ◽

Terminal Domain ◽

Castrate Resistant ◽

Amino Terminal Domain

Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance ◽

Development of novel androgen receptor inhibitors to overcome castrate-resistant prostate cancer

10.1016/b978-0-12-821310-0.00007-3 ◽

2021 ◽

pp. 23-46

Author(s):

Hilal Saraç ◽

Artem Cherkasov ◽

Nathan A. Lack

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Abstract 148: Glucocorticoid receptor-mediated cell survival following androgen receptor blockade in castrate-resistant prostate cancer

10.1158/1538-7445.am2012-148 ◽

2012 ◽

Cited By ~ 1

Author(s):

Kristen Otto ◽

Don Vander Griend ◽

Suzanne Conzen ◽

Russell Szmulewitz

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Glucocorticoid Receptor ◽

Cell Survival ◽

Receptor Blockade ◽

Abstract 2924: Constitutively active androgen receptor splice variants function independently of full-length androgen receptor in a cell-based model of castrate-resistant prostate cancer

10.1158/1538-7445.am2012-2924 ◽

2012 ◽

Cited By ~ 10

Author(s):

Peter E. Lonergan ◽

Lucas P. Nacusi ◽

Lucy J. Schmidt ◽

Kevin M. Regan ◽

Furkan U. Ertem ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Splice Variants ◽

Full Length ◽

A Cell ◽

Castrate Resistant ◽

Androgen Receptor Splice Variants ◽

Constitutively Active

Abstract 3630: Non-enrichment based method for analysis of androgen receptor expression in circulating tumor cells (CTCs) in patients with metastatic castrate resistant prostate cancer

10.1158/1538-7445.am2012-3630 ◽

2012 ◽

Author(s):

Mitchell E. Gross ◽

Daniel C. Lazar ◽

Edward H. Cho ◽

Madelyn Luttgen ◽

Maria L. Uson ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Tumor Cells ◽

Circulating Tumor Cells ◽

Receptor Expression ◽

Androgen Receptor Expression ◽

Abstract 4599: Negative feedback loop between serum response factor and androgen receptor in castrate-resistant prostate cancer

10.1158/1538-7445.am2014-4599 ◽

2014 ◽

Author(s):

Maria Prencipe ◽

Gillian O'Hurley ◽

Amanda O'Neill ◽

Dara Lundon ◽

Lan K. Nguyen ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Negative Feedback ◽

Feedback Loop ◽

Serum Response Factor ◽

Negative Feedback Loop ◽

Response Factor ◽

Castrate Resistant ◽

Serum Response

Abstract 87: Targeting androgen receptor acetylation as a treatment for castrate-resistant prostate cancer

10.1158/1538-7445.am2015-87 ◽

2015 ◽

Author(s):

Erin Heine ◽

Diane E. Merry ◽

Scott Dehm ◽

Karen E. Knudsen ◽

Heather L. Montie

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Abstract 2820: Effects of a CDK 4/6 inhibitor, G1T38, in androgen receptor sensitive and resistant models of castrate resistant prostate cancer

10.1158/1538-7445.am2016-2820 ◽

2016 ◽

Author(s):

James P. Stice ◽

Hannah S. White ◽

Suzanne E. Wardell ◽

Alex Y. Yllanes ◽

Scott A. Lawrence ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Abstract C7: Targeting the androgen receptor with novel combination therapeutic strategies in metastatic/castrate-resistant prostate cancer

Cancer Research ◽

10.1158/1538-7445.prca2012-c7 ◽

2012 ◽

Vol 72 (4 Supplement) ◽

pp. C7-C7

Author(s):

Leigh Ellis ◽

Swathi Ramakrishnan ◽

Shengyu Ku ◽

Roberto Pili

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Therapeutic Strategies ◽

Immunohistochemistry-based assessment of androgen receptor status and the AR-null phenotype in metastatic castrate resistant prostate cancer

Prostate Cancer and Prostatic Diseases ◽

10.1038/s41391-020-0214-6 ◽

2020 ◽

Vol 23 (3) ◽

pp. 507-516

Author(s):

Sounak Gupta ◽

Chad Vanderbilt ◽

Wassim Abida ◽

Samson W. Fine ◽

Satish K. Tickoo ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Receptor Status ◽

Null Phenotype ◽