Analysis of Clinical Effect of Interbody Fusion and Internal Fixation on Degenerative Scoliosis

2021 ◽  
Vol 7 (5) ◽  
pp. 1373-1377
Author(s):  
Lei Sun ◽  
Xiaoren Wang ◽  
Haifeng Guo ◽  
Dongwei Yang
Keyword(s):  
Internal Fixation ◽  
Cobb Angle ◽  
Interbody Fusion ◽  
Clinical Effect ◽  
Clinical Symptoms ◽  
Linear Regression Analysis ◽  
Adjacent Segment ◽  
Degenerative Lumbar Scoliosis ◽  
Degenerative Scoliosis

In this study, we analyzed the clinical effect of interbody fusion and internal fixation on degenerative scoliosis. Methods: After degenerative lumbar scoliosis (DLS) surgery, patients were retrospectively evaluated using VAS (Visual Analogue Scale) and ODI (Oswestry Disability Index) to evaluate clinical efficacy. All patients underwent posterior lumbar decompression laminectomy, pedicle screw internal fixation and posterolateral bone graft fusion.Imaging measurements include scoliosis Cobb angle, fusion Cobb angle, intervertebral angle (AIA), sagittal intervertebral angle (SIA), and lumbar lordosis angle. The relationship between these parameters was tested by binary Pearson analysis and linear regression analysis. Results: Before surgery, the Cobb angle of the scoliosis segment was 15.3°, and it dropped to 10.1° immediately after the operation (P <0.05). Compared with preoperative and postoperative values (2.4°2.7 and 2.1 °2.3, respectively; P <0.05), AIA increased significantly (4.3°3.3) at the last follow-up. However, scoliosis Cobb angle and AIA were not related to VAS or ODI scores. At the final follow-up, no patients developed pseudoarthritis or internal device-related complications. Conclusion: Intervertebral bone fusion and internal fixation resulted in limited DLS correction, and the correction effect decreased over time. The AIA between the upper adjacent segment and the proximal fusion vertebrae continues to increase after surgery, but it does not worsen the clinical symptoms, which is reflected in the lower reoperation rate of the adjacent level of repair recurrence rate.

scholarly journals Adjacent Segment Disease After Posterior Lumbar Interbody Fusion: A Case Series of 1000 Patients

2018 ◽  
Vol 8 (7) ◽  
pp. 722-727 ◽  
Author(s):  
Shinya Okuda ◽  
Tomoya Yamashita ◽  
Tomiya Matsumoto ◽  
Yukitaka Nagamoto ◽  
Tsuyoshi Sugiura ◽  
...  
Keyword(s):  
Interbody Fusion ◽  
Degenerative Spondylolisthesis ◽  
Posterior Lumbar Interbody Fusion ◽  
Adjacent Segment Disease ◽  
Adjacent Segment ◽  
Degenerative Lumbar Scoliosis ◽  
Lumbar Interbody Fusion ◽  
Time Period ◽  
Time Periods

Study Design: Retrospective study. Objective: There have been few reports of adjacent segment disease (ASD) after posterior lumbar interbody fusion (PLIF) with large numbers and long follow-up. The purpose of this study was to investigate (1) ASD incidence and time periods after primary PLIF, (2) repeat ASD incidence and time periods, and (3) ASD incidence and time periods by fusion length, age, and preoperative pathologies. Methods: A total of 1000 patients (average age 67 years, average follow-up 8.3 years) who underwent PLIF for degenerative lumbar disorders were reviewed. ASD was defined as a symptomatic condition in which revision surgery was required. Results: The overall ASD rate was 9.0%, and the average ASD period was 4.7 years after primary surgery. With respect to clinical features of ASD, degenerative spondylolisthesis at the cranial fusion segment was the most frequent. In terms of repeat ASD, second and third ASD incidences were 1.1% and 0.4%, respectively. As for ASD by fusion length, age, and preoperative pathologies, ASD incidence was increased by fusion length, while the time period to ASD was significantly shorter in elderly patients and those with degenerative lumbar scoliosis. Conclusions: In the present study, the overall ASD incidence was 9.0%, and the average ASD period was 4.7 years after primary operation. Second and third ASD incidences were 1.1% and 0.4%, respectively. Fusion length affected the ASD incidence, while aging factor and preoperative pathology affected the ASD time period.

scholarly journals The clinical and radiographic outcomes of stand-alone Oblique Lateral Interbody Fusion in Treatment of Adult Degenerative Scoliosis

2019 ◽  
Author(s):  
Chen Liu ◽  
Xin Ge ◽  
Yu Zhang ◽  
Liang Xiao ◽  
Hongguang Xu
Keyword(s):  
Cobb Angle ◽  
Lumbar Lordosis ◽  
Interbody Fusion ◽  
Degenerative Scoliosis ◽  
Adult Degenerative Scoliosis ◽  
Radiographic Outcomes ◽  
The Mean ◽  
Oblique Lateral Interbody Fusion ◽  
Lateral Interbody

Abstract Background The minimally invasive treatment for adult degenerative scoliosis has become more and more popular. The purpose of this study was to evaluate the efficiency of stand-alone oblique lateral interbody fusion for the treatment of adult degenerative scoliosis in terms of clinical and radiological outcomes. Methods A total of 18 patients with ADS who underwent stand-alone OLIF in our hospital from July 2017 to May 2018 were enrolled in the study. Clinical evaluations were performed with visual analogue scale (VAS) and Oswestry Disability Index (ODI). Radiographic outcomes were recorded in terms of coronal Cobb angle and lumbar lordosis. Results Mean patient age was 62.4 years, 50% of patients were female. Average follow up was 18.4 months. The average operative duration was 87.4 minutes, whilst the mean estimated blood loss was 45.6 ml. Mean coronal Cobb angle corrected from preoperative 15.2° to the final follow-up 6.8° (p < 0.05); and mean lumbar lordosis improved from preoperative 30.0° to 39.4° (p < 0.05). Mean disc height increased from preoperative 0.7 cm to 1.1 cm at final follow-up (p < 0.05). Mean VAS improved from 5.5 to 2.2 (p < 0.05). The mean preoperative and the final follow-up Oswestry Disability Indices were 27.8% and 13.1% respectively (p < 0.05). Conclusions Stand-alone OLIF could be regarded as an efficient and safe option in the treatment of ADS for careful selected patients.

scholarly journals Clinical value of oblique lateral lumbar interbody fusion combined with posterior navigation and long segment internal fixation in the treatment of degenerative scoliosis

2020 ◽  
Author(s):  
Yuliang Lou ◽  
Hui Fei ◽  
Feng Hong ◽  
Canfeng Wang ◽  
Renfu Quan
Keyword(s):  
Blood Loss ◽  
Internal Fixation ◽  
Cobb Angle ◽  
Interbody Fusion ◽  
Operation Time ◽  
Lumbar Interbody Fusion ◽  
Intervertebral Space ◽  
Degenerative Scoliosis ◽  
Short Term ◽  
Lateral Lumbar Interbody Fusion

Abstract Background ：To assess the short-term clinical outcomes of oblique lateral lumbar interbody fusion (OLIF) combined with multiple level fixation with the guidance of posterior "O" arm CT navigation for degenerative scoliosis. Methods ：A total of 15 patients (3 males and 12 females; average age: 62.2±5.3 years) with degenerative scoliosis were enrolled in our study. All patients were treated with OLIF combined with posterior "O" arm CT navigation and long segment (T 10 -L 5 ) internal fixation during Apr. 2016 and Dec. 2017. Collected perioperative data included surgery time, blood loss, excellent rate of intraoperative pedicle screw. Coronal Cobb angle, lumbar lordosis (LL), intervertebral space height, sagittal balance (SVA) were measured by plain radiograph. Accuracy of pedicle screw placement and intervertebral fusion was investigated with postoperative CT. Visual analogue scale (VAS) and Oswestry disability index (ODI) were used to evaluate the clinical efficacy of surgery. Results ： All patients were followed for 12-25 months (16.5±5.3 months).The OLIF operation time was (98.7±16.8) min, and the blood loss was (50.2±10.7) ml. The posterior "O" arm CT-navigated long segment internal fixation was (101.5 ± 23.4) min, and the blood loss was (63.1 ± 19.7) ml. The total operation time was (200.2±40.2) min, and the blood loss was (113.3±30.4) ml. Coronal Cobb angle, LL, intervertebral space height, SVA, VAS, ODI at the last follow-up were 5.5°± 3.1°, 39.3°± 9.1°, (10.9±1.2) mm, (25.1±10.9) mm, (1.3± 0.8)and(15.8±4.5)%, respectively, showing statistically significant differences ( P <0.05). The "O" arm CT navigation has 240 nails, and the excellent rate of three-dimensional scanning of the "O" arm during surgery is 96%. Lumbar CT showed lumbar fusion at the 6-month postoperative period. Conclusion ： The short-term clinical outcomes of oblique lateral lumbar interbody fusion combined with posterior "O" arm CT-navigated long segment internal fixation for degenerative scoliosis are satisfactory, with advantages like minimal invasiveness, accurate navigation, high bone fusion rate and few complications. Keywords ：Scoliosis; Surgery,computer-assisted; Spine fusion

Topping-off technique for stabilization of lumbar degenerative instabilities in 322 patients

2020 ◽  
Vol 32 (3) ◽  
pp. 366-372
Author(s):  
Sandro M. Krieg ◽  
Nele Balser ◽  
Haiko Pape ◽  
Nico Sollmann ◽  
Lucia Albers ◽  
...  
Keyword(s):  
Patient Satisfaction ◽  
Interbody Fusion ◽  
Smooth Transition ◽  
Lumbar Pain ◽  
Adjacent Segment ◽  
Lumbar Interbody Fusion ◽  
Rod System ◽  
Reoperation Rates ◽  
Topping Off

OBJECTIVESemi-rigid instrumentation (SRI) was introduced to take advantage of the concept of load sharing in surgery for spinal stabilization. The authors investigated a topping-off technique in which interbody fusion is not performed in the uppermost motion segment, thus creating a smooth transition from stabilized to free motion segments. SRI using the topping-off technique also reduces the motion of the adjacent segments, which may reduce the risk of adjacent segment disease (ASD), a frequently observed sequela of instrumentation and fusion, but this technique may also increase the possibility of screw loosening (SL). In the present study the authors aimed to systematically evaluate reoperation rates, clinical outcomes, and potential risk factors and incidences of ASD and SL for this novel approach.METHODSThe authors collected data for the first 322 patients enrolled at their institution from 2009 to 2015 who underwent surgery performed using the topping-off technique. Reoperation rates, patient satisfaction, and other outcome measures were evaluated. All patients underwent pedicle screw–based semi-rigid stabilization of the lumbar spine with a polyetheretherketone (PEEK) rod system.RESULTSImplantation of PEEK rods during revision surgery was performed in 59.9% of patients. A median of 3 motion segments (range 1–5 segments) were included and a median of 2 motion segments (range 0–4 segments) were fused. A total of 89.4% of patients underwent fusion, 73.3% by transforaminal lumbar interbody fusion (TLIF), 18.4% by anterior lumbar interbody fusion (ALIF), 3.1% by extreme lateral interbody fusion (XLIF), 0.3% by oblique lumbar interbody fusion (OLIF), and 4.9% by combined approaches in the same surgery. Combined radicular and lumbar pain according to a visual analog scale was reduced from 7.9 ± 1.0 to 4.0 ± 3.1, with 56.2% of patients indicating benefit from surgery. After maximum follow-up (4.3 ± 1.8 years), the reoperation rate was 16.4%.CONCLUSIONSThe PEEK rod concept including the topping-off principle seems safe, with at least average patient satisfaction in this patient group. Considering the low rate of first-tier surgeries, the presented results seem at least comparable to those of most other series. Follow-up studies are needed to determine long-term outcomes, particularly with respect to ASD, which might be reduced by the presented approach.

Obesity may be associated with adjacent-segment degeneration after single-level transforaminal lumbar interbody fusion in spinopelvic-mismatched patients with a minimum 2-year follow-up

2021 ◽  
Vol 34 (1) ◽  
pp. 83-88
Author(s):  
Ping-Guo Duan ◽  
Praveen V. Mummaneni ◽  
Minghao Wang ◽  
Andrew K. Chan ◽  
Bo Li ◽  
...  
Keyword(s):  
Interbody Fusion ◽  
Transforaminal Lumbar Interbody Fusion ◽  
Adjacent Segment Degeneration ◽  
Adjacent Segment ◽  
Lumbar Interbody Fusion ◽  
Inclusion Criteria ◽  
Single Level ◽  
Degenerative Lumbar Spondylolisthesis ◽  
Surgery Rates

OBJECTIVEIn this study, the authors’ aim was to investigate whether obesity affects surgery rates for adjacent-segment degeneration (ASD) after transforaminal lumbar interbody fusion (TLIF) for spondylolisthesis.METHODSPatients who underwent single-level TLIF for spondylolisthesis at the University of California, San Francisco, from 2006 to 2016 were retrospectively analyzed. Inclusion criteria were a minimum 2-year follow-up, single-level TLIF, and degenerative lumbar spondylolisthesis. Exclusion criteria were trauma, tumor, infection, multilevel fusions, non-TLIF fusions, or less than a 2-year follow-up. Patient demographic data were collected, and an analysis of spinopelvic parameters was performed. The patients were divided into two groups: mismatched, or pelvic incidence (PI) minus lumbar lordosis (LL) ≥ 10°; and balanced, or PI-LL < 10°. Within the two groups, the patients were further classified by BMI (< 30 and ≥ 30 kg/m2). Patients were then evaluated for surgery for ASD, matched by BMI and PI-LL parameters.RESULTSA total of 190 patients met inclusion criteria (72 males and 118 females, mean age 59.57 ± 12.39 years). The average follow-up was 40.21 ± 20.42 months (range 24–135 months). In total, 24 patients (12.63% of 190) underwent surgery for ASD. Within the entire cohort, 82 patients were in the mismatched group, and 108 patients were in the balanced group. Within the mismatched group, adjacent-segment surgeries occurred at the following rates: BMI < 30 kg/m2, 2.1% (1/48); and BMI ≥ 30 kg/m2, 17.6% (6/34). Significant differences were seen between patients with BMI ≥ 30 and BMI < 30 (p = 0.018). A receiver operating characteristic curve for BMI as a predictor for ASD was established, with an AUC of 0.69 (95% CI 0.49–0.90). The optimal BMI cutoff value determined by the Youden index is 29.95 (sensitivity 0.857; specificity 0.627). However, in the balanced PI-LL group (108/190 patients), there was no difference in surgery rates for ASD among the patients with different BMIs (p > 0.05).CONCLUSIONSIn patients who have a PI-LL mismatch, obesity may be associated with an increased risk of surgery for ASD after TLIF, but in obese patients without PI-LL mismatch, this association was not observed.

Outcomes of 2-level posterior lumbar interbody fusion for 2-level degenerative lumbar spondylolisthesis

2013 ◽  
Vol 19 (1) ◽  
pp. 90-94 ◽  
Author(s):  
Hironobu Sakaura ◽  
Tomoya Yamashita ◽  
Toshitada Miwa ◽  
Kenji Ohzono ◽  
Tetsuo Ohwada
Keyword(s):  
Lumbar Spine ◽  
Clinical Outcome ◽  
Interbody Fusion ◽  
Sagittal Alignment ◽  
Posterior Lumbar Interbody Fusion ◽  
Adjacent Segment ◽  
Lumbar Interbody Fusion ◽  
Single Level ◽  
The Mean

Object A systematic review concerning surgical management of lumbar degenerative spondylolisthesis (DS) showed that a satisfactory clinical outcome was significantly more likely with adjunctive spinal fusion than with decompression alone. However, the role of adjunctive fusion and the optimal type of fusion remain controversial. Therefore, operative management for multilevel DS raises more complicated issues. The purpose of this retrospective study was to elucidate clinical and radiological outcomes after 2-level PLIF for 2-level DS with the least bias in determination of operative procedure. Methods Since 2005, all patients surgically treated for lumbar DS at the authors' hospital have been treated using posterior lumbar interbody fusion (PLIF) with pedicle screws, irrespective of severity of slippage, patient age, or bone quality. The authors conducted a retrospective review of 20 consecutive cases involving patients who underwent 2-level PLIF for 2-level DS and had been followed up for 2 years or longer (2-level PLIF group). They also analyzed data from 92 consecutive cases involving patients who underwent single-level PLIF for single-level DS during the same time period and had been followed for at least 2 years (1-level PLIF group). This second group served as a control. Clinical status was assessed using the Japanese Orthopaedic Association (JOA) score. Fusion status and sagittal alignment of the lumbar spine were assessed by comparing serial plain radiographs. Surgery-related complications and the need for additional surgery were evaluated. Results The mean JOA score improved significantly from 12.8 points before surgery to 20.4 points at the latest follow-up in the 2-level PLIF group (mean recovery rate 51.8%), and from 14.2 points preoperatively to 22.5 points at the latest follow-up in the single-level PLIF group (mean recovery rate 55.3%). At the final follow-up, 95.0% of patients in the 2-level PLIF group and 96.7% of those in the 1-level PLIF group had achieved solid spinal fusion, and the mean sagittal alignment of the lumbar spine was more lordotic than before surgery in both groups. Early surgery-related complications, including transient neurological complications, occurred in 6 patients in the 2-level PLIF group (30.0%) and 11 patients in the 1-level PLIF group (12.0%). Symptomatic adjacent-segment disease was found in 4 patients in the 2-level PLIF group (20.0%) and 10 patients in the 1-level PLIF group (10.9%). Conclusions The clinical outcome of 2-level PLIF for 2-level lumbar DS was satisfactory, although surgery-related complications including symptomatic adjacent-segment disease were not negligible.

Clinical Effect of Vertebral Column Decancellation Osteotomy Combined with Ponte Osteotomy in Elderly Patients with Old Thoracolumbar Fracture Combined with Kyphosis Deformity

2021 ◽  
Vol 7 (5) ◽  
pp. 3878-3887
Author(s):  
Tongtong Zhang ◽  
Chao Kong ◽  
Xiangyao Sun ◽  
Wei Wang ◽  
Shudong Jiang ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Cobb Angle ◽  
Vertebral Column ◽  
Clinical Effect ◽  
Life Quality ◽  
Thoracolumbar Fracture ◽  
Thoracolumbar Kyphosis ◽  
Ponte Osteotomy ◽  
Vas Score

Objective. The purpose of this study was to investigate the clinical effect of vertebral column decancellation (VCD) osteotomy combined with Ponte osteotomy in elderly patients withold thoracolumbar fracture combined with kyphosis deformity.Methods.36 elderly patients with old thoracolumbar fracture combined with kyphosis deformity admitted to our hospital from August 2015 to November 2018 were selected as the study subjects, and all of them were treated with VCDosteotomy combined with Ponte osteotomy.The Cobb angle of thoracolumbar kyphosis, sagittal vertical axis (SVA), visual analog scale (VAS) score.Oswestry disability index (ODI) and life quality were compared at 1 week before and after surgery as well as at the last follow-up. Results. ® All the 36 patients underwent the surgery successfully without serious complications, with the average duration of surgery of (5.13±0.62) h, average blood loss of (821.58±142.67) ml and average hospital stay of (14.02±2.43) d. (2) The Cobb angle of thoracolumbar kyphosis and SVA at 1 week after surgery and at the last follow-up were smaller than those at 1 week before surgery (P < 0.01), but the Cobb angle of thoracolumbar kyphosis and SVA at the last follow-up were slightly larger than those at 1 week after surgery (P < 0.01). (3) The VAS score and ODI score at 1 week after surgery and at the last follow-up were lower than those before surgery (P < 0.01), and the VAS score and ODI score at the last follow-up were lower than those at 1 week after surgery (P < 0.01). @ The scoliosis research society 22-item (SRS-22) score at the last follow-up was higher than that before surgery (P < 0.01). Conclusion. VCD osteotomy combined with Ponte osteotomy in the treatment of old thoracolumbar fracture combined with kyphosis deformity in the elderly can reduce the Cobb angle of thoracolumbar kyphosis, improve sagittal balance, reduce pain symptoms and functional disorders, and improve patents’ life quality, having a good clinical effect.

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