First Experience of Multifocal and Toric Extended Depth of Focus Intraocular Lenses Implantation (Short-Term Analysis)

Aim. Analysis of the functional results of new IOL with an extended depth of focus implantation a in the short-term (6 months) follow-up period.Patients and methods. The prospective study included 27 patients (40 eyes) after bilateral (n = 12) or monolateral (n = 15) implantation of EDOF IOL Tecnis Symfony with an average follow-up period of 6.5 ± 0.2 (6–7) months. In all cases, IOL implantation was preceded by cataract phacoemulsification or removal of the transparent lens for refractive purposes. The age range was from 39 to 78 (60.6 ± 10.1) years. EDOF IOL Tecnis Symfony ZXR00 was implanted in 30 eyes, and toric EDOF IOL Tecnis Symfony ZXT100, ZXT150, ZTX225, and ZXT300 were implanted in 10 eyes in the presence of clinically significant astigmatism.Results. An increase in UCNVA from 0.18 ± 0.04 to 0.79 ± 0.11, UCIVA from 0.21 ± 0.07 to 0.89 ± 0.10, UCDVA from 0.24 ± 0.06 to 0.95 ± 0.16, BCNVA from 0.61 ± 0.05 to 0.80 ± 0.03, BCIVA from 0.58 ± 0.10 to 0.97 ± 0.19, and BCDVA from 0.65 ± 0.08 to 1.0 ± 0.06 (p < 0.05 in all cases). The spherical equivalent of refraction decreased from –4.5 ± 1.8 in the preoperative period to –0.18 ± 0.92 in the follow-up period of 6 months after implantation of the Tecnis Symfony ZXR00 IOL. In the group with toric IOLs, a decrease in the cylindrical component of refraction was shown from 1.33 ± 1.02 (modulo) to 0.61 ± 0.44 (modulo) during the maximum observation period. In all cases, the rotational stability of the implanted IOLs was noted. In 9 patients out of 24 (37.5 %), permanent or periodic optical phenomena were detected, of which 4 patients (16.7 %) had halos, 3 (12.5 %) had glare, and 2 (8.3 %) had difficulty driving in the dark. These side effects did not affect the overall patient satisfaction — 22 patients (91.7 %) rated the result of the operation as “excellent”, and 2 patients (8.3 %) — as “good”.Conclusion. The paper presents an analysis of the first experience in the Russian Federation of implantation of new IOLs with extended depth of focus and their toric version in 27 patients. Data on the effectiveness of this IOL for vision correction at all distances, low frequency of side optical phenomena, and high patient satisfaction are presented. Further comparative studies with other multifocal IOLs are needed.

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Analys of multifocal and toric extended depth of focus intraocular lenses implantation

Modern technologies in ophtalmology ◽

10.25276/2312-4911-2021-5-76-79 ◽

2021 ◽

pp. 76-79

Author(s):

K.B. Pershin ◽

◽

N.F. Pashinova ◽

А.I. Tsygankov ◽

E.A. Antonov ◽

...

Keyword(s):

Patient Satisfaction ◽

Functional Results ◽

Intraocular Lenses ◽

Rotational Stability ◽

Depth Of Focus ◽

Multifocal Iol ◽

Extended Depth Of Focus ◽

Toric Iols ◽

Optical Phenomena

Purpose. Analysis of the functional results of new IOL with an extended depth of focus implantation a in the short-term (6 months) follow-up period. Material and methods. The prospective study included 27 patients (40 eyes) after bilateral (n=12) or monolateral (n=15) implantation of EDOF IOL Tecnis Symfony with an average follow-up period of 6.5±0.2 (6-7) months. In all cases, IOL implantation was preceded by cataract phacoemulsification or removal of the transparent lens for refractive purposes. The age range was from 39 to 78 (60.6±10.1) years. EDOF IOL Tecnis Symfony ZXR00 was implanted in 30 eyes, and toric EDOF IOL Tecnis Symfony ZXT100, ZXT150, ZTX225, and ZXT300 were implanted in 10 eyes in the presence of clinically significant astigmatism. Results. An increase in UCNVA from 0.18±0.04 to 0.79±0.11, UCIVA from 0.21±0.07 to 0.89±0.10, UCDVA from 0.24±0.06 to 0.95±0.16, BCNVA from 0.61±0.05 to 0.80±0.03, BCIVA from 0.58±0.10 to 0.97±0.19, and BCDVA from 0.65±0.08 to 1.0±0.06 (p<0.05 in all cases). The spherical equivalent of refraction decreased from -4.5±1.8 in the preoperative period to -0.18±0.92 in the follow-up period of 6 months after implantation of the Tecnis Symfony ZXR00 IOL. In the group with toric IOLs, a decrease in the cylindrical component of refraction was shown from 1.33±1.02 (modulo) to 0.61±0.44 (modulo) during the maximum observation period. In all cases, the rotational stability of the implanted IOLs was noted. In 9 patients out of 24 (37.5%), permanent or periodic optical phenomena were detected, of which 4 patients (16.7%) had halos, 3 (12.5%) had glare, and 2 (8.3%) had difficulty driving in the dark. These side effects did not affect the overall patient satisfaction – 22 patients (91.7%) rated the result of the operation as "excellent", and 2 patients (8.3%) – as "good". Conclusion. The paper presents an analysis of the first experience in the Russian Federation of implantation of new multifocal and toric IOLs with extended depth of focus in 27 patients. Data on the effectiveness of this IOL for vision correction at all distances, low frequency of side optical phenomena, and high patient satisfaction are presented. Further comparative studies with other multifocal IOLs are needed. Key words: cataract; presbyopia; multifocal IOL; IOL with extended depth of focus; EDOF; Symphony.

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Clinical Outcomes after Mix-and-Match Implantation of Extended Depth of Focus and Diffractive Multifocal Intraocular Lenses

Journal of Ophthalmology ◽

10.1155/2021/8881794 ◽

2021 ◽

Vol 2021 ◽

pp. 1-7

Author(s):

Jae Hyuck Lee ◽

Ho Seok Chung ◽

Su Young Moon ◽

So Young Park ◽

Hun Lee ◽

...

Keyword(s):

Visual Acuity ◽

Patient Satisfaction ◽

Cataract Surgery ◽

Clinical Outcomes ◽

Intraocular Lenses ◽

Prospective Clinical Study ◽

Depth Of Focus ◽

Near Vision ◽

Extended Depth Of Focus ◽

Mix And Match

Purpose. To evaluate the clinical outcomes after bilateral mix-and-match cataract surgery using extended depth of focus (EDOF) and diffractive multifocal (DMF) intraocular lenses (IOLs). Setting. Asan Medical Center, Seoul, South Korea. Design. Prospective clinical study. Methods. Thirty-seven patients underwent TECNIS Symfony EDOF IOL (ZXR00) implantation in the dominant eye, and TECNIS +3.25 DMF IOL (ZLB00) implantation in the nondominant eye. Patients were followed up for 3 months; uncorrected and corrected distance visual acuity (UDVA and CDVA), uncorrected intermediate and near visual acuity (UIVA and UNVA), contrast sensitivity, defocus curves, stereopsis, and patient satisfaction were assessed. Results. At 3 months, the mean logarithm of the minimum angle of resolution (logMAR) of UDVA was 0.07 ± 0.09 in EDOF IOL eyes, 0.12 ± 0.11 in DMF IOL eyes, and 0.02 ± 0.05 in both eyes. UIVA was 0.11 ± 0.11 in EDOF IOL eyes, 0.16 ± 0.12 in DMF IOL eyes, and 0.04 ± 0.07 in both eyes. UNVA was 0.25 ± 0.15 in EDOF IOL eyes, 0.22 ± 0.16 in DMF IOL eyes, and 0.13 ± 0.13 in both eyes. Thirty patients (81.1%) were more than satisfied with near vision, and 8 patients (21.6%) complained of severe glare and halo. Spectacle independence for near vision was achieved in 34 patients (91.9%), and 31 patients (83.8%) had better than a 50-second arc of stereopsis. Conclusion. Mix-and-match cataract surgery with EDOF and DMF IOL implantation provided good visual outcomes for all distances. Additionally, excellent patient satisfaction was achieved with a high level of spectacle independence and acceptable photic phenomena.

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Depth of focus and functional results in patients with multifocal intraocular lenses: A long-term follow-up

Journal of Cataract & Refractive Surgery ◽

10.1016/s0886-3350(13)80335-5 ◽

1993 ◽

Vol 19 (6) ◽

pp. 685-689 ◽

Cited By ~ 19

Author(s):

Gerd U. Auffarth ◽

Wilfried Hunold ◽

Thomas A. Wesendahl ◽

Ekkehard Mehdorn

Keyword(s):

Functional Results ◽

Intraocular Lenses ◽

Depth Of Focus ◽

Multifocal Intraocular Lenses ◽

Long Term Follow Up

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Clinical Outcomes After Mix-and-Match Implantation of Extended Depth of Focus and Diffractive Multifocal Intraocular Lenses

10.20944/preprints202004.0423.v1 ◽

2020 ◽

Author(s):

Jae Hyuck Lee ◽

Ho Seok Chung ◽

Su Young Moon ◽

Hun Lee ◽

Jae Yong Kim ◽

...

Keyword(s):

Visual Acuity ◽

Patient Satisfaction ◽

Cataract Surgery ◽

Clinical Outcomes ◽

Intraocular Lenses ◽

Depth Of Focus ◽

Near Vision ◽

Extended Depth Of Focus ◽

Dominant Eye ◽

Mix And Match

Purpose: To evaluate clinical outcomes after bilateral mix-and-match cataract surgery using extended depth of focus (EDOF) and diffractive multifocal (DMF) intraocular lenses (IOLs). Methods: Thirty-seven patients received Tecnis Symfony EDOF IOL (ZXR00) implantation in the dominant eye, and Tecnis +3.25 DMF IOL (ZLB00) in the non-dominant eye. Patients were followed for 3 months, and uncorrected and corrected distance visual acuity (UDVA, CDVA) , uncorrected intermediate and near visual acuity (UIVA, UNVA), contrast sensitivity, defocus curves, stereopsis, and patient satisfaction were assessed. Results: At 3 months, mean logMAR UDVA was 0.07 ± 0.09 in EDOF IOL eyes, 0.12 ± 0.11 in DMF IOL eyes, and 0.02 ± 0.05 in both eyes. UIVA was 0.11 ± 0.11 in EDOF IOL eyes, 0.16 ± 0.12 in DMF IOL eyes, and 0.04 ± 0.07 in both eyes. UNVA was 0.25 ± 0.15 in EDOF IOL eyes, 0.22 ± 0.16 in DMF IOL eyes, and 0.13 ± 0.13 in both eyes. Thirty patients(81.1%) were more than satisfied with near vision, and 8 patients(21.6%) complained of severe glare and halo. Spectacle independence for near vision was achieved in 34 patients(91.9%), and 31 patients(83.8%) had better than a 50 second arc of stereopsis. Conclusion: Mix-and-match cataract surgery with EDOF and DMF IOL implantation provided good visual outcomes through all distances. Also excellent patient satisfaction was achieved with high level of spectacle independence and minimal photic phenomena.

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Visual Outcomes and Patient Satisfaction for Trifocal, Extended Depth of Focus and Monofocal Intraocular Lenses

Journal of Refractive Surgery ◽

10.3928/1081597x-20190618-01 ◽

2019 ◽

Vol 35 (7) ◽

pp. 434-440 ◽

Cited By ~ 1

Author(s):

Luba Rodov ◽

Olga Reitblat ◽

Adi Levy ◽

Ehud I. Assia ◽

Guy Kleinmann

Keyword(s):

Patient Satisfaction ◽

Intraocular Lenses ◽

Depth Of Focus ◽

Visual Outcomes ◽

Extended Depth Of Focus

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Comparison of trifocal or hybrid multifocal-extended depth of focus intraocular lenses: a systematic review and meta-analysis

Scientific Reports ◽

10.1038/s41598-021-86222-1 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Yueyang Zhong ◽

Kai Wang ◽

Xiaoning Yu ◽

Xin Liu ◽

Ke Yao

Keyword(s):

Systematic Review ◽

Visual Acuity ◽

Meta Analysis ◽

Visual Quality ◽

Intraocular Lenses ◽

Depth Of Focus ◽

Refractive Lens Exchange ◽

Extended Depth Of Focus ◽

Refractive Lens ◽

Near Visual Acuity

AbstractThis meta-analysis aimed to evaluate the clinical outcomes following implantation of trifocal intraocular lenses (IOLs) or a hybrid multifocal-extended depth of focus (EDOF) IOL in cataract or refractive lens exchange surgeries. We examined 13 comparative studies with bilateral implantation of trifocal (898 eyes) or hybrid multifocal-EDOF (624 eyes) IOLs published through 1 March 2020. Better uncorrected and corrected near visual acuity (VA) were observed in the trifocal group (MD: − 0.143, 95% CI: − 0.192 to − 0.010, P < 0.001 and MD: − 0.149, 95% CI: − 0.217 to − 0.082, P < 0.001, respectively), while the hybrid multifocal-EDOF group presented better uncorrected intermediate VA (MD: 0.055, 95% CI: 0.016 to 0.093, P = 0.005). Trifocal IOLs were more likely to achieve spectacle independence at near distance (RR: 1.103, 95% CI: 1.036 to 1.152, P = 0.002). The halo photic effect was generated more frequently by the trifocal IOLs (RR: 1.318, 95% CI: 1.025 to 1.696, P = 0.031). Contrast sensitivity and subjective visual quality yielded comparable results between groups. Trifocal IOLs demonstrated better performance at near distance but apparently led to more photic disturbances. Our findings provided the most up-to-date and comprehensive evidence by comparing the benefits of advanced IOLs in clinical practice.

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Functional Results and Photic Phenomena with new Extended-Depth-of-Focus Intraocular Lens

10.21203/rs.2.10020/v3 ◽

2019 ◽

Author(s):

Bert C. Giers ◽

Ramin Khoramnia ◽

Dorottya Varadi ◽

Hannah Wallek ◽

Hyeck Soo Son ◽

...

Keyword(s):

Intraocular Lens ◽

Functional Results ◽

High Rate ◽

Patient Questionnaire ◽

Depth Of Focus ◽

Reading Acuity ◽

Extended Depth Of Focus ◽

Electronic Reading ◽

Letter Size ◽

Reading Distance

Abstract Background: Evaluation of clinical and functional results of a new extended depth of focus intraocular lens (EDOF-IOL). Methods: Fourteen cataract patients (twenty-eight bilateral implantations) were assessed for uncorrected (UDVA) and corrected (CDVA) distance visual acuities; uncorrected (UNVA), distance-corrected (DCNVA) and best corrected (CNVA) near visual acuities; and uncorrected (UIVA) and distance-corrected (DCIVA) intermediate visual acuities - as well as binocular defocus curves. Photopic and mesopic contrast sensitivity was recorded. Reading acuity was evaluated using an electronic reading desk at fixed distances and at the patient’s preferred near and intermediate distances. Visual symptoms were assessed with a halo and glare simulator plus a patient questionnaire which also recorded quality of life. Results: Median postoperative monocular UDVA was 0.13logMAR (range -0.08 to 0.42logMAR), median CDVA was -0.01logMAR (range -0.20 to 0.22logMAR), median UIVA at 80 cm was -0.05logMAR (range -0.18 to 0.58logMAR) and median UNVA at 40 cm was 0.14logMAR (range -0.10 to 0.64logMAR). Binocular uncorrected reading acuity was 0.10logMAR at 40 cm and 0.11logMAR at 80 cm. Patients preferred a median intermediate reading distance of 62.8 cm over the predetermined 80 cm, which allowed them to read smaller letter size but did not improve reading acuity. Patients reported a high rate of spectacle independence and satisfaction in everyday life and little to no dysphotopsia. Conclusion: The Mini WELL Ready IOL provided good postoperative functional results at far and intermediate distances and improved the visual and reading acuity at reading distance. The lens caused little to no dysphotopsia.

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