scholarly journals Presentation of pulmonary tuberculosis in diabetics and response to anti-tuberculosis therapy

2017 ◽  
Vol 5 (12) ◽  
pp. 5356
Author(s):  
Md Abdul Waseem ◽  
Misba Zahera ◽  
V. Gopalakrishnaiah
Keyword(s):  
Pulmonary Tuberculosis ◽  
Lung Field ◽  
Presenting Symptoms ◽  
Lower Lung Field ◽  
Uncontrolled Diabetes ◽  
Lower Lung ◽  
Sputum Conversion ◽  
Oral Hypoglycaemic Drugs ◽  
Tuberculosis Therapy

Background: Diabetes and Tuberculosis are known to be mutually affective. In high tuberculosis and Diabetes burden country like ours, it is essential that we understand all the aspects concerning both these diseases individually and in mutual coexistence, in order to improve the management of this unhealthy partnership.Methods: This is a prospective hospital based observational study, in which 100 patients with coexisting Diabetes and new sputum confirmed pulmonary tuberculosis with no other comorbidities were included. Detailed history, examination and appropriate investigations were done evaluating the clinical and radiological presentation and treatment response in terms of sputum conversion at follow up visits.Results: Predominant symptoms were anorexia, fever and cough with sputum, majority with duration of more than 4 weeks. About half of them had diabetes duration of less than 1 year, most being newly diagnosed. All cases had upper lobe involvement; two thirds of them had lower lung field and multiple lobe involvement. Confluent consolidation, cavitary lesions and fluffy infiltrates were common. 27 of the 100 cases had a delayed sputum conversion. Longer duration of diabetes, maintenance on oral hypoglycaemic drugs alone and uncontrolled diabetes had delayed sputum conversion.Conclusions: Presenting symptoms of tuberculosis in diabetics is more or less similar to that in non-diabetics. Atypical radiological presentation with lower lung field involvement and confluent consolidation mimicking pneumonia is common. Delay in sputum conversion is common in dual disease and is increased with increasing DM duration and poor glycemic control. Better results may be obtained with insulin therapy.

Abstract 9978: Effect of Balloon Pulmonary Angioplasty on Respiratory Function in Patients With Chronic Thromboembolic Pulmonary Hypertension: Different Effects According to the Lung Field Involved

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Mina Akizuki ◽  
Naoki Serizawa ◽  
Atuko Ueno ◽  
Taku Adachi ◽  
Nobuhisa Hagiwara
Keyword(s):  
Pulmonary Hypertension ◽  
Respiratory Function ◽  
Lower Lobe ◽  
Chronic Thromboembolic Pulmonary Hypertension ◽  
Lung Field ◽  
Lower Lung Field ◽  
Balloon Pulmonary Angioplasty ◽  
Lower Lung ◽  
Thromboembolic Pulmonary Hypertension

Background: Treatment of chronic thromboembolic pulmonary hypertension (CTEPH) with balloon pulmonary angioplasty (BPA) reportedly improves hemodynamics, exercise capacity, and right ventricular function. However, the effect of BPA on respiratory functions is unclear. Methods: We enrolled consecutive patients with inoperable CTEPH who underwent BPA. BPA was performed primarily on the lower lobe arteries during the first series and on the upper and middle lobe arteries during the second series. We examined right heart catheterization, the respiratory function test, and the cardiopulmonary exercise test, and compared the change in these parameters according to the BPA performed field (divided into the upper-middle and lower lobe before BPA, after BPA, and the follow-up period). Results: In total, 62 BPA sessions were performed in 13 CTEPH patients. Hemodynamics significantly improved after BPA (mPAP: 44±8 to 24±5 mmHg, PVR: 818±383 to 293±68 dyne/s/cm-5), and WHO-FC improved from 3.1±0.3 to 2.2±0.6 after BPA. Hemodynamic improvement tended to be larger in BPA in the lower lung field. The %DLco significantly decreased (p=0.001) in BPA in the lower lung field, and did not appear to recover during the follow-up period. In contrast, %DLco significantly increased in BPA in the upper-middle lung field (p=0.030), and tended to increase until the follow-up period (p=0.077) (Fig). In addition, VE/VCO2 slope significantly improved after BPA in the lower lung field (p=0.014), and showed further improvement at the follow-up period (p=0.007); however, VE/VCO2 slope remained unchanged after BPA in the upper-middle lung field (Fig). Furthermore, during follow-up, change in %DLco and VE/VCO2 slope were significantly different between lower and upper-middle lung field BPA performed (p<0.001 and p=0.020, respectively, Fig). Conclusions: We observed that the effect of BPA in CTEPH patients may have a different effect on respiratory function according to the lung field.

Metastatic choriocarcinoma with multiple neoplastic intracranial microaneurysms

2008 ◽  
Vol 108 (5) ◽  
pp. 1014-1017 ◽  
Author(s):  
In Bok Chang ◽  
Byung Moon Cho ◽  
Se Hyuck Park ◽  
Dae Young Yoon ◽  
Sae Moon Oh
Keyword(s):  
Ct Scan ◽  
Cerebral Arteries ◽  
Lung Field ◽  
Necrotizing Vasculitis ◽  
Cerebral Angiogram ◽  
Lower Lung Field ◽  
Metastatic Lesions ◽  
Middle Cerebral Arteries ◽  
Lower Lung ◽  
Chest Ct Scan

✓The authors report on a case of a metastatic choriocarcinoma that mimicked systemic necrotizing vasculitis on a cerebral angiogram. A 35-year-old woman presented with right hemiplegia and a drowsy mental state. A computed tomography (CT) scan revealed an intracerebral hemorrhage in the left frontal region. A cerebral angiogram showed multiple microaneurysms arising from the bilateral anterior cerebral arteries and middle cerebral arteries, and the renal angiogram showed multiple microaneurysms arising from the left distal renal artery. A chest CT scan revealed multiple metastatic lesions in the left lower lung field. The hematoma and microaneurysms were surgically removed. Choriocarcinoma was diagnosed after histological examination. Despite receiving postoperative chemotherapy, the patient died 1 month after the operation.

scholarly journals A Clinical Study on the Lower Lung Field Tuberculosis

1985 ◽  
Vol 32 (2) ◽  
pp. 86-92
Author(s):  
Hee Young Sohn ◽  
Eun Kyun Woo ◽  
Sang Ho Chang ◽  
Sung Kyu Kim ◽  
Won Young Lee ◽  
...  
Keyword(s):  
Clinical Study ◽  
Lung Field ◽  
Lower Lung Field ◽  
Lower Lung

Lower Lung Field Tuberculosis

Tuberculosis ◽  
2009 ◽  
pp. 227-227
Author(s):  
SK Sharma ◽  
G Ahluwalia
Keyword(s):  
Lung Field ◽  
Lower Lung Field ◽  
Lower Lung

scholarly journals Clinicoradiological Profile of Lower Lung Field Tuberculosis Cases among Young Adult and Elderly People in a Teaching Hospital of Madhya Pradesh, India

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Saurabh Kumar Singh ◽  
Kamlesh Kumar Tiwari
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Clinical Feature ◽  
Lung Field ◽  
X Rays ◽  
Lower Lung Field ◽  
Radiological Features ◽  
Lower Lung ◽  
Stage Renal Disease ◽  
End Stage

Aim. To study the clinical and radiological features of lower lung field tuberculosis (LLFTB) in relation to the patients of nonlower lung field tuberculosis (non-LLFTB).Material and Methods. All the patients of lower lung field tuberculosis defined by the lesions below an arbitrary line across the hila in their chest X-rays were included in the study. Their sputum for acid fast bacilli, HIV, blood sugar, and other relevant investigations were performed.Results. The total of 2136 cases of pulmonary tuberculosis was studied. Among them 215 (10%) cases of patients were diagnosed as the case of lower lung field tuberculosis. Females (62%) were more commonly affected. Most common clinical feature in non-LLFTB was cough (69%) followed by fever (65%), chest pain (54.7%), and weight loss (54.4%). Chest X-ray showed predominance of right side (60.9%) in cases of LLFTB. The relative risk of having the LLFTB in diabetes patients, HIV seropositive patients, end stage renal disease patients, and patients on corticosteroid therapy was high.Conclusion. Lower lung field tuberculosis is not an uncommon entity. It is more common in diabetes, HIV positive, end stage renal disease, and corticosteroid treated patients. Clinical and radiological features are different from upper lobe tuberculosis patients.

Lower Lung Field Tuberculosis

1944 ◽  
Vol 10 (6) ◽  
pp. 481-488 ◽  
Author(s):  
SAMUEL S. ROMENDICK ◽  
BERNARD FRIEDMAN ◽  
HERBERT F. SCHWARTZ
Keyword(s):  
Lung Field ◽  
Lower Lung Field ◽  
Lower Lung

scholarly journals Nutritional effect, care and support for patients with tuberculosis among diabetes: a study from Warangal district

2017 ◽  
Vol 4 (1) ◽  
pp. 59
Author(s):  
Sireesha Tanniru ◽  
Syed Asha ◽  
Lavanya Poonem ◽  
Divya Murahari ◽  
Malathi Jojula ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Bacterial Infections ◽  
Lung Field ◽  
Early Diabetes ◽  
Lower Lung Field ◽  
Nutritional Effect ◽  
Rural And Urban ◽  
Clinical Investigations ◽  
Care And Support ◽  
Lower Lung

Objective: Tuberculosis is one of the important infections among the diabetes as per our study and survey reports. Diabetes mellitus has been reported to modify the presenting features of pulmonary tuberculosis, but there are varying data, particularly regarding the association with lower lung field involvement. In our study we would like to determine whether diabetes mellitus alters the clinical and radiographic manifestations of tuberculosis in hosts and to define the determinants of lower lung field involvement due to effect of nutrition supply.Methods: A total of 500 diabetes were identified from both rural and urban population and were confirmed the diabetic status based on questioner and consent of patients. Off 500 patients 200 suspects with bronchial infections was tested for other bacterial and Tuberculosis infections by Grams staining, and culture on Nutrient and blood Agar for bacterial infections based on the staining and culture they were identified to be grams positive or Grams negative bacterial infections.Results: We had conducted a survey and study in Warangal and adjoing districts of Telangana state during 2014- 2017 period, in the study we had counseled approximately 1000 -2000 populations off which 500 were suspects for early diabetes based on the symptoms and clinical investigations off 500 were able to found 200 diabetic type 2 causes.  Off 200 55 were positive for tuberculosis all the suspects were counseled for their nutritional status and other prevailing side effects with treatment. Conclusions: Based on this study we had tried to evaluate the effect, care and support of nutritional among diabetic TB patients.

Tuberculosis of the Lower Lung Field

1980 ◽  
Vol 10 (4) ◽  
pp. 401-404
Author(s):  
S. Naraqi ◽  
M. Voibun
Keyword(s):  
Lung Field ◽  
Lower Lung Field ◽  
Lower Lung
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