scholarly journals Role of image guided fine needle aspiration cytology in the diagnosis of intra-abdominal and intra-thoracic lesions

Author(s):  
Mehnaz Choudhary ◽  
Rajat Gupta ◽  
Kuldeep Singh

Background: Intrathoracic and intra-abdominal tumors at inaccessible sites pose difficulty in diagnosis. Ultrasonography and computed tomography guided fine needle aspiration cytology has an important role in the diagnosis and distinguishing them as benign and malignant lesions. Image guided FNA has proved to be safe, quick, reliable and cost-effective method for obtaining tissue for cytopathological examination. The objective was to describe the pattern of intra-abdominal and intra thoracic masses on FNAC.Methods: This cross-sectional study was done in the postgraduate Department of pathology Government, Medical college Jammu i.e. 1st September 2017 to 30th September,2018 for a period of one year under image guided FNAC. Air dried and wet fixed smears were stained with may Grunwald Giemsa (MGG) and Papinacolau (PAP) stains respectively. Acid fast bacilli stain was done on additional smears in case of suspected tubercular lesions.Results: A total of 60 patients were subjected to ultrasonography and CT guided intra-abdominal and intra thoracic FNACs in a period of one year. FNAC was performed from various anatomical sites of which intra-abdominal lesions were 40 (liver:21 cases, gallbladder:8 cases, ovary: 3 cases, lymph nodes 3 cases, pancreas: 2 cases, omentum 2 cases, GIT 1 case).  Intrathoracic lesions were twenty (20); out of which lung cases were eighteen (18) and two (2) were mediastinal aspirations.Conclusions: Percutaneous fine needle aspiration cytology under image guidance well described the pattern of deep-seated lesions.

2021 ◽  
Vol 8 (23) ◽  
pp. 1927-1931
Author(s):  
Alaka Sahu ◽  
Santosh Gudaganatti ◽  
Swetalina Pandey

BACKGROUND Fine-needle aspiration cytology (FNAC) is an easy, minimally invasive and useful investigation, and is considered important next to imaging in the rapid diagnosis of lung neoplasm for the last few decades. The purpose of this study was to evaluate the role of image-guided FNAC in pulmonary neoplasm, analyse the results and correlate with cell block histopathological findings. METHODS This is a cross sectional study conducted over a period of two years, involving fifty patients. All the clinical and radiological data were studied from the consenting patient. Then they underwent image-guided FNAC. The cytology smears and cell blocks were evaluated simultaneously to stick out a definitive diagnosis. RESULTS Out of all the 50 cases, we found the necessary FNAC smears and cell block material only in 41 cases. The age range varied from 18 to 90 years with a peak in the fifth to sixth decades. Benign lesions were 4 and malignant were 23 as shown by cytology study. Malignancy was proved in 27 cases in histopathology. The most common tumour was adenocarcinoma (41 %) followed by squamous cell carcinoma (19.5 %). Complications after the procedure were minimal and were noted only in two cases. CONCLUSIONS Image-guided fine needle aspiration cytology of lung tumours provide uncomplicated, cost effective, and a rapid method, for reaching a reliable diagnosis for lung neoplasms with minimum complication. KEYWORDS FNAC, Histological Correlation, Pulmonary Neoplasm


2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Rajneesh Madhok ◽  
Ashish Gupta ◽  
Lalit Singh ◽  
Tanu Agarwal

INTRODUCTION: The study is an attempt to evaluate the sensitivity, specificity, positive predictive value, negative predictive value, p Value and complications of CT guided thoracic interventions fine needle aspiration cytology and core biopsy which are used for diagnosing benign and malignant thoracic lesions. MATERIAL AND METHODS: Study included 102 Patients (87 males and 15 females) with age group ranged from 15 to 87 years.A total of 143 CT guided interventions (84 FNAC’s and 59 core biopsies) were performed in 102 patients. The tissue obtained was sent to the laboratory for histopathological and cytological analysis for a final diagnosis which would contribute to patient management. RESULTS: All( 59) core biopsies were successful in procuring adequate tissue for histopathological analysis and the yield of core biopsies was 100% .However out of 84 FNAC’s only 4 were unsuccessful in procuring adequate tissue with a failure rate of 4.8%. Post procedural biopsy complications were only three (2.1%) which were small pneumothorax. There were 75 malignant lesions and 23 benign lesions based on cytology and histopathology (4 were excluded due to inadequate sample). There was good agreement between benign and malignant lesions diagnosed on CT and that diagnosed by pathology. The most common benign and malignant lesions were granulomatous lesion and squamous cell carcinoma. CONCLUSION: Percutaneous CT guided interventions like core biopsy and fine needle aspirations cytology are simple minimal invasive procedures with good patient acceptance and low morbidity and almost negligible mortality. CT guided interventions should be performed early for diagnosis of thoracic lesions.


CHEST Journal ◽  
1997 ◽  
Vol 112 (2) ◽  
pp. 423-425 ◽  
Author(s):  
Luigi Santambrogio ◽  
Mario Nosotti ◽  
Nadia Bellaviti ◽  
Gianni Pavoni ◽  
Ferdinando Radice ◽  
...  

2013 ◽  
Vol 11 (1) ◽  
pp. 37-41
Author(s):  
Rajive Raj Shahi ◽  
Mukunda Singh Shrestha ◽  
Sujata Pant ◽  
Sunil Singh ◽  
Dinesh Maharjan

Introduction: Following the first study of Computed tomography guided trans thoracic biopsy of lung lesion by Haaga and Alfidi in 1976, CT guided transthoracic biopsy has been widely used for confirming the diagnosis of suspicious lung lesions. This study is aimed to assess the effectiveness of Transthoracic percutaneous fi ne needle aspiration cytology and frequency of associated complications. Methods: A retrospective, hospital based study was performed between 11/06/2008 and 1/12/2009 at Department of Radiology, Shree Birendra Hospital, Kathmandu, Nepal. Thirty nine consecutive cases of lung lesions who underwent Trans Thoracic Percutaneous Fine Needle Aspiration Cytology (TTFNAC) under CT guidance were analysed. Smears of the aspirated material were evaluated by the pathology consultant (cytopathological evaluation) for adequacy. Results: There was adequate material for a cytopathological diagnosis in thirty four (87.18 %) cases. Two cases were hemorrhagic while three cases revealed only reactive cells thus inadequate and non representative case constituted (12.8 %). Eight cases were reported as benign (23.53 %). Twenty three samples (67.65%) were reported as definite malignant cases and three cases (8.82%) showed atypical cells, suggestive of malignancy. Squamous cell carcinoma was the single most frequent histological diagnosis (12 cases). Conclusions: The FNAC of lung is useful, safe and economical technique providing 87% diagnostic accuracy for lung mass without significant increase in complications. Medical Journal of Shree Birendra Hospital; Jan-June 2012/vol.11/Issue1/37-41 DOI: http://dx.doi.org/10.3126/mjsbh.v11i1.7766


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