Cytopathologic Evaluation of Image-Guided Fine-Needle Aspiration Cytology and Cell Block Correlation for Lung Neoplasm in a Tertiary Care Hospital VIMSAR, Burla - A Cross-Sectional Study

BACKGROUND Fine-needle aspiration cytology (FNAC) is an easy, minimally invasive and useful investigation, and is considered important next to imaging in the rapid diagnosis of lung neoplasm for the last few decades. The purpose of this study was to evaluate the role of image-guided FNAC in pulmonary neoplasm, analyse the results and correlate with cell block histopathological findings. METHODS This is a cross sectional study conducted over a period of two years, involving fifty patients. All the clinical and radiological data were studied from the consenting patient. Then they underwent image-guided FNAC. The cytology smears and cell blocks were evaluated simultaneously to stick out a definitive diagnosis. RESULTS Out of all the 50 cases, we found the necessary FNAC smears and cell block material only in 41 cases. The age range varied from 18 to 90 years with a peak in the fifth to sixth decades. Benign lesions were 4 and malignant were 23 as shown by cytology study. Malignancy was proved in 27 cases in histopathology. The most common tumour was adenocarcinoma (41 %) followed by squamous cell carcinoma (19.5 %). Complications after the procedure were minimal and were noted only in two cases. CONCLUSIONS Image-guided fine needle aspiration cytology of lung tumours provide uncomplicated, cost effective, and a rapid method, for reaching a reliable diagnosis for lung neoplasms with minimum complication. KEYWORDS FNAC, Histological Correlation, Pulmonary Neoplasm

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Role of cell block in cytopathologic evaluation of image-guided fine needle aspiration cytology

Journal of Cytology ◽

10.4103/joc.joc_82_15 ◽

2017 ◽

Vol 34 (3) ◽

pp. 133 ◽

Cited By ~ 3

Author(s):

ElizabathP Mathew ◽

Vijayalakshmi Nair

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Cell Block ◽

Aspiration Cytology ◽

Fine Needle ◽

Image Guided ◽

Needle Aspiration Cytology

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Role of image guided fine needle aspiration cytology in the diagnosis of intra-abdominal and intra-thoracic lesions

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20191640 ◽

2019 ◽

Vol 7 (5) ◽

pp. 1584

Author(s):

Mehnaz Choudhary ◽

Rajat Gupta ◽

Kuldeep Singh

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Cross Sectional ◽

Ct Guided ◽

Fine Needle ◽

Image Guided ◽

Needle Aspiration Cytology ◽

One Year

Background: Intrathoracic and intra-abdominal tumors at inaccessible sites pose difficulty in diagnosis. Ultrasonography and computed tomography guided fine needle aspiration cytology has an important role in the diagnosis and distinguishing them as benign and malignant lesions. Image guided FNA has proved to be safe, quick, reliable and cost-effective method for obtaining tissue for cytopathological examination. The objective was to describe the pattern of intra-abdominal and intra thoracic masses on FNAC.Methods: This cross-sectional study was done in the postgraduate Department of pathology Government, Medical college Jammu i.e. 1st September 2017 to 30th September,2018 for a period of one year under image guided FNAC. Air dried and wet fixed smears were stained with may Grunwald Giemsa (MGG) and Papinacolau (PAP) stains respectively. Acid fast bacilli stain was done on additional smears in case of suspected tubercular lesions.Results: A total of 60 patients were subjected to ultrasonography and CT guided intra-abdominal and intra thoracic FNACs in a period of one year. FNAC was performed from various anatomical sites of which intra-abdominal lesions were 40 (liver:21 cases, gallbladder:8 cases, ovary: 3 cases, lymph nodes 3 cases, pancreas: 2 cases, omentum 2 cases, GIT 1 case). Intrathoracic lesions were twenty (20); out of which lung cases were eighteen (18) and two (2) were mediastinal aspirations.Conclusions: Percutaneous fine needle aspiration cytology under image guidance well described the pattern of deep-seated lesions.

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Cell Block and Its Impact in the Diagnosis of Jaw Lesions over Fine Needle Aspiration Cytology

Acta Cytologica ◽

10.1159/000517166 ◽

2021 ◽

pp. 1-7

Author(s):

Kaveri Hallikeri ◽

Biji Babu ◽

Archana Sudhakaran ◽

Roshni Monteiro

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Dentigerous Cyst ◽

Needle Aspiration ◽

Histopathological Diagnosis ◽

Cell Block ◽

Aspiration Cytology ◽

Fine Needle ◽

Dentigerous Cysts ◽

Needle Aspiration Cytology

Objectives: To determine the role and efficacy of fine needle aspiration cytology (FNAC) and cell block in diagnosis of jaw lesions and compare the agreement between FNAC and cell block to predict the diagnosis. Method: The sample comprised 51 cases, including 12 odontogenic keratocysts (OKCs), 8 ameloblastomas, 22 radicular cysts, 7 dentigerous cysts, and 1 each of intraosseous mucoepidermoid carcinoma (MEC) and adenomatoid odontogenic tumor (AOT). FNAC samples remaining after hematoxylin and eosin (H&E)-stained cytosmear diagnosis were centrifuged at 3,000 rpm for 10 min. The supernatant was discarded and sediment mixed with 2–3 mL alcohol and filtered. To this, 10% formalin was added, filtered, taken for routine processing, and stained with H&E. The result of FNAC smear and cell block was compared with histopathological diagnosis. Results: On cytological examination of the smears, 7 OKCs and 22 radicular cysts were diagnosed, whereas ameloblastomas, AOT, intraosseous MEC, and dentigerous cysts were not. This gave an agreement of 56.8% with the biopsy reports. Cell block sections stained with H&E of 12 OKCs, 22 radicular cysts, 1 MEC, and 3 cases of ameloblastoma offered a diagnosis in accordance with the biopsies giving an agreement of 74.5%, while dentigerous cyst and AOT failed to do so. In comparison with FNAC, additionally 5 cases of OKC and 1 of MEC could be detected, and in ameloblastoma, out of 8 cases, only 3 yielded a concordant diagnosis through the cell block technique. Conclusion: In comparison with FNAC, the architectural pattern and the morphology of the cells were better preserved by the cell block technique. This substantiates that cell block could be used as an ancillary technique to aid in definitive diagnosis of head and neck swellings.

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