scholarly journals An evaluation of health-related quality of life and its determinants among people living with HIV/AIDS attending tertiary care hospital of Kurnool, India

Author(s):  
S. Cynthia Subhaprada ◽  
Shasank R. V. S. S. ◽  
T. Sivakala ◽  
S. Madhusai

Background: HIV/AIDS is known to affect an individual not only physically but also mentally, socially, and financially. It is a syndrome that builds a vacuum in a person affecting his/her life as a whole. Combined with ART, Quality of life (QoL) is an important component in the evaluation of the wellbeing of people living with HIV/AIDS (PLHIV). The objective of this study is to assess health related quality of life of HIV/AIDS patients attending ART clinic Tertiary care hospital, GGH, Kurnool and to determine the association of socio-demographic and disease related variables with health related quality of life.Methods: A cross-sectional study was conducted from April 2019 to June 2019 involving 400 purposively selected HIV-positive patients of age >18 years, who were taking highly active anti-retroviral therapy for the past 6months from the ART center, GGH, Kurnool. After obtaining IEC clearance and informed consent, WHOQOL-BREF instrument was used for data collection. Data analysis was performed using IBM SPSS version 26.0.Results: Out of the 400 participants, 60% were males. The mean age of the participants was 38.5±10.54 years. Overall quality of life had a mean score of 69.71. Physical (82.57) and level of independence (78.78) domains showed higher mean score when compared to psychological (63.82), environmental (61.49) and Social (60.26) domains.Conclusions: Among study subjects 15.5% had excellent QoL (≥80), nearly 69.75% had good QoL (60-79) and 14.75% had poor QoL (<60). Low QoL scores were seen in the social domain, suggesting that more social interventions are required in this population.

2020 ◽  
Author(s):  
Fikadu Tadesse Nigusso ◽  
Azwihangwisi Helen Mavhandu-Mudzusi

Abstract Background: Health-related quality of life (HRQoL) serves as a direct measure of individuals’ health, life expectancy and the impact that the utilization of health care has on quality of life. The purpose of this study is to assess the HRQoL of people living with HIV/AIDS (PLWHA), and to ascertain its association with the social inequalities and clinical determinants among people living with HIV in Benishangul Gumuz Regional State, Ethiopia.Methods: A cross-sectional study was conducted between December 2016 and February 2017; 390 people at two referral hospitals and three health centers participated in the study. The Patient-Reported Outcomes Measurement Information System Global Health Scale (PROMIS Global 10) was used to measure key HRQoL domains. Physical Health Summary (PHS) and Mental Health Summary (MHS) scores were employed. PHS and MHS scores below 50 (the standardized mean score) were determined to be poor and above 50 to be good. Bivariate and multivariate logistic regression analyses were used to identify factors associated with PHS and MHS scores. Results: This study included 259 (66.4%) females and 131 (33.6%) males. The PHS scores ranged from 16.2 to 67.7 with a mean of 48.8 (SD = 8.9). Almost 44.6% of the study population has a PHS score of below 50; the MHS scores ranged from 28.4 to 67.6 with a mean of 50.8 (SD = 8.1). About 41.8% of the study population has an MHS score of below 50. Unemployment, household food insecurity and comorbidities with HIV were associated with both poor PHS and poor MHS scores. Age below 25 years and being a member of Christian fellowship were inversely associated with poor PHS. The least wealth index score and CD4 count below 350 cells/mL were also associated with poor MHS. Conclusion: Overall, socioeconomic inequalities and HIV-related clinical factors play an important role in improving the HRQoL of PLWHA. Many of these determinants are alterable risk factors. Appropriate strategies can improve the holistic management of chronic HIV care and maximize PLWHAs’ HRQoL. Such strategies require the adoption of comprehensive interventions, including policies and programmes that would improve the health, wellbeing and livelihood of PLWHA.


2015 ◽  
Vol 11 (2) ◽  
pp. 7-14 ◽  
Author(s):  
S Timilsina ◽  
K Regmi

Introduction: Assessing the health related quality of life (HQoL) and depression in human immunodeficiency virus (HIV) positive people and TB-HIV co infected people is of extreme importance in designing strategies and implementing interventional programs on treatment care and support to People living with HIV and AIDS. Methodology: A cross-sectional study was conducted among People living with HIV/AIDS and TB-HIV Co infection from July to December 2011 at care and support canters in Kathmandu, Nepal. The list HIV care and Support centre registered at Kathmandu were selected using the lottery proportionately to meet the sample size of 154. The method of data collection was summarized in the World Health Organization’s questionnaire for Health related Quality of life and Beck Depression Inventory Scale II for depression. Data was collected using verbal information of respondents, entered on Epi Data version3.4.1 and analyzed using SPSS version 16.0. Results: TB-HIV co infected people had lower quality of life in all domains compared to HIV/AIDS infected people. The prevalence of depression was found higher in TB-HIV co infected people than HIV/AIDS group. CD4 count, educational status, occupation, ethnicity, family size and depression were statistically significant with the QoL domains. Among co infected patients, depression was 3.86 times more likely to influence QoL while adjusted odds ratio was 4.21 times higher. Conclusion: The TB control program should design strategies to improve the quality of life of TB-HIV co infected people and depression should be targeted as an intervention to improve the quality of life of people living with HIV with or without TB.DOI: http://dx.doi.org/10.3126/saarctb.v11i2.12428SAARC J TUBER LUNG DIS HIV/AIDS, 2014;XI(2) Page: 7-14   


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Issifou Yaya ◽  
Lihanimpo Djalogue ◽  
Akouda Akessiwè Patassi ◽  
Dadja Essoya Landoh ◽  
Ayélé Assindo ◽  
...  

2004 ◽  
Vol 26 (6) ◽  
pp. 371-376 ◽  
Author(s):  
Janeen Hughes ◽  
Jennifer Jelsma ◽  
Emilou Maclean ◽  
Marta Darder ◽  
Xolani Tinise

2020 ◽  
Author(s):  
Girma Tekle Gebremariam ◽  
Kalikdan Yihenew Bitew ◽  
Yemisrach Tessema Weldeyes ◽  
Atalay Mulu Fentie ◽  
Gebremedhin Beedemariam Gebretekle

Abstract Background: Antiretroviral therapy (ART) has significantly reduced mortality and morbidity of people living with HIV/AIDS (PLWHA); however, the nature of infection and treatment associated with adverse drug reactions often adversely affect patient's health-related quality of life (HRQoL). The purpose of this study was to assess the HRQoL and its associated factors among PLWHA in Ethiopia.Methods: A hospital-based cross-sectional study was conducted among patients taking HAART at Zewditu Memorial General Hospital in Addis Ababa. A face-to-face interview was performed using the HIV/AIDS targeted quality of Life (HAT-QoL) instrument. Patients who met eligibility criteria were approached consecutively while they came to the pharmacy for a medication refill. Descriptive statistics were used to present patient characteristics and HRQoL profiles. Independent t-test and one-way ANOVA were carried out to identify predictors for HRQoL. All statistical tests considered significant at p-value < 0.05.Results: A total of 300 participants were interviewed. The mean age of patients was 41.47 ± 9.45 years and the majority (63.13% ) were females. More than two-thirds (69.7%) of patients were adherents to their medication. The highest HAT-QoL mean score was observed in the overall function domain (84.96±19.87) followed by life satisfaction (83.02±14.61) and physician trust (80.53±20.79). Moderate mean scores were reported in the domains of health worries (71.90±27.00), medication worries (69.44±21.53) and disclosure worries (63.65±30.94) had moderate mean scores, while HIV mastery (56.94±32.52), financial worries (48.81±44.64), and sexual function (12.57±45.56) recorded lower mean scores. Being female, higher educational status, older age, low household income, taking prophylactic therapy, low CD4+ count, and non-adherence were significantly associated with HAT-QoL domains.Conclusions: Overall, HIV/AIDS patients in Addis Ababa had an average level of HRQoL. This study demonstrated that several sociodemographic and clinical variables contribute to reduced HRQoL. Hence, healthcare providers should be paid attention to associated factors that contributed to reduced HRQoL.


2015 ◽  
Vol 1 (1) ◽  
pp. 1-15 ◽  
Author(s):  
Safiya George Dalmida ◽  
◽  
Harold G. Koenig ◽  
Marcia McDonnell Holstad ◽  
Tami L. Thomas ◽  
...  

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