scholarly journals Bilateral sudden sensorineural hearing loss in a patient with scrub typhus: a case report

Author(s):  
Mosin Babu ◽  
Thingbaijam Sudhiranjan Singh ◽  
Shandhyalata Yumlembam ◽  
Nimitha A. M. Juhy ◽  
Shapam Ravi Meetei

<p class="abstract">Scrub typhus is a febrile illness caused by Orientia tsutsugamushi, a gram negative alpha proteobacterium and transmitted by the bite of leptotrombidium, chigger mite larvae. The disease is endemic to Southeast Asia and Northern Australia and derives its name from the vegetation that harbours the mite. The patient usually presents with high-grade fever, an eschar at the inoculation site, generalised lymphadenopathy, organomegaly and pneumonitis. Rarely, the patient may go into acute renal failure, disseminated intravascular coagulation and shock. A case of scrub typhus presenting with acute sensorineural hearing loss which resolved with treatment is being reported. Hearing impairment with fever in a patient in endemic region of scrub typhus can give a clue to health care worker towards the diagnosis of scrub typhus and thus early administration of treatment.</p>

2017 ◽  
Vol 22 (03) ◽  
pp. 245-249 ◽  
Author(s):  
Ahmed Khater ◽  
Mohammad El-Anwar ◽  
Ahmad Nofal ◽  
Atef Elbahrawy

Introduction Idiopathic sudden sensorineural hearing loss (ISSNHL) is hearing loss of at least 30 dB in at least 3 contiguous frequencies within at least 72 hours. There are many different theories to explain it, and many different modalities are used for its management, such as: systemic steroids (SSs), intratympanic steroid injection (ITSI), hyperbaric oxygen therapy (HOT), antiviral drugs, and vasodilators or vasoactive substances. Objectives This study aims to evaluate the efficacy of the combination of the most common treatment modalities of ISSNHL and to compare the results if HOT was not one of the treatment modalities administered. Methods The study was conducted with 22 ISSNHL patients with ages ranging from 34 to 58 years. The patients were divided into 2 groups; group A included 11 patients managed by SSs, ITSI, antiviral therapy, and HOT simultaneously, and group B included 11 patients exposed to the aforementioned modalities, with the exception of HOT. Results After one month, all of the patients in group A showed total improvement in hearing in all frequencies, with pure tone average (PTA) of 18.1 ± 2.2, while in group B, 5/11 (45.5%) patients showed total improvement, and 6 /11 (54.5%) patients showed partial improvement, with a total mean PTA of 28.1 ± 8.7. Conclusion The early administration of HOT in combination with other clinically approved modalities (SSs, ITSI, antiviral therapy) provides better results than the administration of the same modalities, with the exception of HOT, in the treatment of ISSNHL.


2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
RanveerSingh Jadon ◽  
J Dixit ◽  
Animesh Ray ◽  
Piyush Ranjan ◽  
NK Vikram ◽  
...  

2017 ◽  
Vol 6 (34) ◽  
pp. 2856-2857
Author(s):  
Dhanashree Ananthashayana Iyengar ◽  
Devraj Sharma ◽  
Ravinder Singh Minhas ◽  
Madhuri Dadwal ◽  
Shaweta Shaweta

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Sean M. Anderson ◽  
Daniel Gold ◽  
Gregory Olson ◽  
Jennifer Pisano

Abstract Background Enterovirus has been described as a cause of aseptic meningitis in humorally immunosuppressed patients. Case presentation A 67-year-old female with a history of mantle cell lymphoma on rituximab therapy presented with subacute hepatitis, myalgias, and sensorineural hearing loss several months after an initial febrile illness. She was diagnosed with enterovirus infection by CSF PCR as a unifying etiology of her presentation, representing an unusual presentation of disease. Discussion and conclusions This patient’s unique presentation and clinical course presents important implications in the care of similarly immunosuppressed patients with cryptic complaints.


1994 ◽  
Vol 10 (4) ◽  
pp. 169-171 ◽  
Author(s):  
Desouky F. Fayed ◽  
Nabil S. Dahmash

Objective: To report a case of erythromycin-induced ototoxicity and to discuss the occurrence of this event. Case Summary: A 26-year-old woman was admitted to the medical intensive care unit with a two-day history of progressive shortness of breath, high-grade fever, cough, and pleuritic chest pain. Arterial blood gases on room air showed severe hypoxemia, and a chest X-ray revealed right lower-lobe infiltrates. Provisional diagnosis was atypical pneumonia, for which erythromycin lactobionate 1 g q6h iv was administered. All other chronic medications were maintained at the same dosage and frequency. All laboratory work remained stable. After 36 hours, the patient developed sensorineural hearing loss. Erythromycin was stopped immediately. After 24 hours, there was subjective improvement of hearing, with complete return to pretreatment levels in 72 hours. Discussion: A review of the literature showed only 40 reported cases of reversible ototoxicity, mainly with high dosages of erythromycin (4 g/d). Conclusions: High-dose erythromycin therapy can cause reversible sensorineural hearing impairment. Treatment with erythromycin 4 g/d should be reserved for immunosuppressed patients with Legionnaires' disease and patients with Legionella endocarditis. Patients should have a baseline audiogram and regular monitoring for subjective evidence of sensorineural hearing loss, and the drug should be discontinued if ototoxicity is suspected.


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