scholarly journals Correlation of endometrial thickness by Trans-Vaginal Sonography [TVS] and histopathology in women with abnormal peri-menopausal and postmenopausal bleeding – A prospective study

2018 ◽  
Vol 5 (1) ◽  
pp. 44-48
Author(s):  
Sowmyanarayanan Lavanya ◽  
Swetha Munivenkatappa ◽  
Anthata Jyothsna Sravanthi

Background: The life expectancy of women shows an increase as a result of which women experience a long postmenopausal phase. Postmenopausal bleeding is a worrisome symptom occurring in 10 % of the women, making them seek a gynaecology opinion at the earliest. Women in developed countries have a predilection for developing endometrial cancer whereas cancer cervix still dominates in the developing countries. This prospective study was carried out on 75 women presenting with postmenopausal bleeding to the gynaecology clinic at a tertiary hospital set up. The study aimed to find the incidence of postmenopausal bleeding, age distribution, causes and different evaluation methods to confirm the diagnosis.Methods: The present study is a prospective study conducted on 75 postmenopausal women reporting with postmenopausal bleeding at the gynaecology clinic at a tertiary care hospital.              Results: Menopause was noted above 45 years in 84% of the patients and 16% were in 40-45 years age. Postmenopausal bleeding was observed in 50-60 years in 56% of women and 30% above 60 years. The medical problems associated were hypertension (20%), diabetes (11%), obesity (22%), hypothyroidism (4%). 53 women had benign causes while 22 had malignancy.Conclusions: Benign lesions of the genital tract are common causes of postmenopausal bleeding. Carcinoma cervix and endometrium classically present with postmenopausal bleed. Strong suspicion, thorough evaluation and early diagnosis improve the quality of life and reduce the morbidity and mortality.


Author(s):  
Dr. Richa Choudhary ◽  
Dr. Rishikant Sinha

Objectives: This present study was to evaluate the clinical profile and Transvaginal Doppler Sonography findings of endomterium in women with postmenopausal bleeding. Methods: Detail history, clinical examinations and relevant investigations were performed to all cases of PMB. BMI was calculated. Transvaginal sonography of the uterus and Doppler analysis of the blood flow were performed using vaginal probe at 5-7.5 megahertz. Endometrial thicknesses as well as other pathologies in the cavity were noted. Resistive index was calculated. Results: Data was analyzed by using SPSS version 26 software. One sample statistical methods was used. Mean ± standard deviation was observed. P-value was taken equal to less than 0.05 for significant differences. Conclusions: Highest prevalence of PMB was seen in women with age greater than 50 years. Most of the cases had BMI 20-25 kg/m2. Most of the benign and malignant cases had parity status P3-P4 and P1-P2 respectively. Endometrial thickness of malignant PMB cases was significantly greater than benign PMB cases. Resistive index of malignant PMB women was significantly lower than benign PMB women. Hence, promotion of healthy lifestyles and contraceptives in early reproductive life and awareness for the need of early screening should be recommended to reduce the prevalence of PMB. And early diagnosis and management of post menopausal bleeding are needed for prevention from malignancy. Key words: Postmenopausal Bleeding, Benign, Malignancy, Transvaginal Doppler Sonography.


2001 ◽  
Vol 80 (9) ◽  
pp. 856-862 ◽  
Author(s):  
Rita Sousa ◽  
Margarida Silvestre ◽  
Luis Almeida E Sousa ◽  
Francisco Falcão ◽  
Isabel Dias ◽  
...  

Author(s):  
Pratibha Devabhaktuni ◽  
Padmaja Allani ◽  
Suneetha Komatlapalli ◽  
Rekha Rani Ksheerasagara

Background: Evaluation was done in 100 women presenting with postmenopausal bleeding, (PMB), to discuss the utility of hysteroscopy combined guided endometrial curettage in the diagnosis of uterine cancer and endometrial hyperplasia, and, treat benign lesions, like polyps, synechiae at the same sitting. At MGMH during the years, 2002 to 2006, there were 57 women, and at care, 40 women with PMB during 2011 to 2013, and three in a nursing home, Hyderabad, were investigated.Methods: Evaluation was done in 100 women presenting with PMB by hysteroscopy and curettage to diagnose the cause of PMB and benign lesions like polyps, synechiae were managed by operative hysteroscopy. Bettocchi 5 mm hysteroscope, monopolar instruments and glycine was used for excision of polyps.Results: In one hundred women with PMB, 19% had cancer. Endometrial adenocarcinoma in 14, endocervical carcinoma in 2, uterine carcinosarcoma in 3 cases. All 3 cases of uterine carcinosarcoma on hysteroscopy were large polyps measuring 5×5-6 cm size. Atypical hyperplasia endometrium in 7% and simple hyperplasia in 17%, was reported on histopathology, in cases with hyperplastic endometrium on hysteroscopy. Benign polyps in 41% were managed at the same sitting by operative hysteroscopy.Conclusions: Women with postmenopausal bleeding must have USG, trans vaginal sonography (TVS), endometrial thickness (ET) measurement, preferably endometrial echo complex (EEC). In women with PMB, the risk of uterine cancer would be 19%, i.e., 1 out of 5 women. Atypical hyperplasia in 7%. Hysteroscopy guided curettage, with histopathology, is the gold standard protocol in cases of PMB.


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