scholarly journals A comparative study of serum uric acid, serum lactate dehydrogenase and serum calcium in hypertensive disorders of pregnancy and normal pregnancy

2019 ◽  
Vol 6 (1) ◽  
pp. 90-94
Author(s):  
Prerana Deokar ◽  
◽  
Meghal Mehta ◽  
Abhay Nagdeote
Keyword(s):  
Uric Acid ◽  
Lactate Dehydrogenase ◽  
Comparative Study ◽  
Serum Uric Acid ◽  
Serum Calcium ◽  
Normal Pregnancy ◽  
Serum Lactate ◽  
Serum Lactate Dehydrogenase ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders

scholarly journals Evaluation of serum lactate dehydrogenase in hypertensive disorders of pregnancy and its comparison with normal pregnancy

2020 ◽  
Vol 9 (8) ◽  
pp. 3270
Author(s):  
Anil Kumar ◽  
Kushla Pathania ◽  
Meenakshi Kandoria
Keyword(s):  
Lactate Dehydrogenase ◽  
Pregnant Women ◽  
Lactic Dehydrogenase ◽  
Serum Lactate ◽  
Morbidity And Mortality ◽  
Serum Lactate Dehydrogenase ◽  
Close Monitoring ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
Subsequent Decrease

Background: Hypertensive disorders of pregnancy and their complications rank as one of the major causes of maternal morbidity and mortality. The objective of the study was to compare the level of serum LDH in normotensive and hypertensive pregnant women and to correlate the levels with maternal and foetal outcome.Methods: Study was conducted in department of obstetrics and gynecology Kamla Nehru State Hospital for Mother and Child, Indira Gandhi Medical College, Shimla w.e.f. 15th July, 2014 to 14th July, 2015. Pregnant women enrolled in the study were divided into following groups: - Group 1- Age and parity matched 202 normotensive pregnant women. Group 2- 202 women with hypertensive disorders of pregnancy as per the inclusion and exclusion criteria. Subjects were also divided according to the serum LDH levels into following groups: LDH <600 IU/L, LDH-600-800 IU/L and LDH >800IU/L. The maternal and foetal outcome was correlated with the serum level of LDH. One-way analysis of variance (ANOVA) and the chi-square test were used to compare the results. Differences were considered significant when p<0.05.Results: Severely preeclamptic and eclamptic patients were significantly younger, with low gravidity and parity. The symptoms and complications of preeclampsia and eclampsia along with perinatal mortality were increased significantly in patients with LDH >800 IU/L as compared with those who had lower levels.Conclusions: Lactate dehydrogenase is a useful biochemical marker that reflects the severity of and the occurrence of complications of preeclampsia and eclampsia. Identification of high-risk patients with elevated levels of lactic dehydrogenase, their close monitoring, and prompt, correct management may prevent these complications, with a subsequent decrease in maternal foetal morbidity and mortality.

scholarly journals To study levels of serum lactate dehydrogenase and serum uric acid in patients suffering from Leukemias

2020 ◽  
Vol 3 (1) ◽  
pp. 242-247
Author(s):  
Dr Kriti Sharma ◽  
Dr. Vijay Mehra ◽  
Dr. Surinder Paul ◽  
Dr. Pashaura Singh ◽  
Dr. Permeet Kaur Bagga ◽  
...  
Keyword(s):  
Uric Acid ◽  
Lactate Dehydrogenase ◽  
Serum Uric Acid ◽  
Serum Lactate ◽  
Serum Lactate Dehydrogenase

scholarly journals Study of the serum uric acid level as a prognostic indicator in hypertensive disorders of pregnancy

2021 ◽  
Vol 10 (9) ◽  
pp. 3441
Author(s):  
Smitha Krishnegowda ◽  
G. Nita
Keyword(s):  
Uric Acid ◽  
Disease Severity ◽  
Serum Uric Acid ◽  
Mode Of Delivery ◽  
Prognostic Indicator ◽  
Maternal Serum ◽  
P Value ◽  
Chronic Hypertension ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders

Background: Abnormal uric acid levels in patients with preeclampsia and eclampsia affect both maternal and fetal outcome negatively. This study was done to know the alterations in these serum levels in comparison to normal pregnancy and also among various hypertensive disorders of pregnancies.Methods: Maternal serum uric acid levels were compared among cases and controls in relation to disease severity, mode of delivery, maternal outcome.Results: In group A (cases), 10 patients had raised uric acid levels, of which 5 were severe preeclampsia, 3 were eclampsia and 2 cases of chronic hypertension superimposed preeclampsia. P value is 0.001 (highly significant). Also serum uric acid is significantly elevated in hypertensive disorders of pregnancy compared with controls with a P value of 0.001.Conclusions: Significant correlation was observed between maternal serum uric acid, disease severity and maternal outcome. Our study concludes that uric acid can be considered as a sensitive prognostic indicator of severity in hypertensive disorders of pregnancy.

scholarly journals Correlation of serum lactate dehydrogenase and uric acid levels with severity parameters of preeclampsia

2019 ◽  
Vol 6 (3) ◽  
pp. 315-320
Author(s):  
Deena C Mendez ◽  
◽  
Mamatha Kunder ◽  
Shashidhar K N ◽  
Munikrishna M ◽  
...  
Keyword(s):  
Uric Acid ◽  
Lactate Dehydrogenase ◽  
Serum Lactate ◽  
Serum Lactate Dehydrogenase

scholarly journals A comparative study of serum uric acid, glucose, calcium and magnesium in pre-eclampsia and normal pregnancy

2017 ◽  
Vol 7 (2) ◽  
pp. 1155-1161
Author(s):  
Arun Dhungana ◽  
Aakriti Bharati ◽  
Rosina Manandhar ◽  
Chanda Karki
Keyword(s):  
Uric Acid ◽  
Lactate Dehydrogenase ◽  
Pregnant Women ◽  
Serum Uric Acid ◽  
Serum Magnesium ◽  
Normal Pregnancy ◽  
Age Group ◽  
Serum Magnesium Level ◽  
Function Impairment ◽  
Calcium And Magnesium

Background: Preeclampsia is associated with liver function abnormalities and renal function impairment. The objective of this study is to compare serum uric acid, glucose, calcium and magnesium in pre-eclampsia with normal pregnancy. Materials and Methods: Normal pregnant women and pre eclamptic women of age group 20-40 years were included. Serum magnesium, calcium, glucose, uric acid were analyzed.Results: Mean serum magnesium level in preeclampsia (1.83 ± 0.21mg/dl) was lesser in comparison to normal pregnant women (2.03 ± 0.16 mg/dl). Serum calcium level was lower (8.10 ±0.56mg/dl) than control (9.59 ±0.62 mg/dl) with p<0.001. Uric acid, glucose and lactate dehydrogenase in preeclamptic women was significantly higher than that in normal pregnant women (6.14 ± 0.85 vs.4.01 ± 0.62, p=<0.001), (94.17± 18.65 vs.86.34 ± 10.19, p=0.033) and ( 466.80 ± 97.29 vs. 194.22 ± 39.76, p=<0.001) respectively.Conclusion: There were significant changes in serum magnesium, uric acid, calcium, glucose, lactate dehydrogenase and total protein in pregnant women.

scholarly journals Raised Uric Acid Level and Fetal Outcome in Hypertensive Disorders of Pregnancy

2014 ◽  
Vol 9 (1) ◽  
pp. 78-81
Author(s):  
A Singh ◽  
P Sharma ◽  
R Malla ◽  
S Singh
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Fetal Outcome ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders

Aims: This study was done to find the relation of raised uric acid with fetal outcome in hypertensive disorders of pregnancy and to compare the fetal outcome with normal and raised uric acid level . Methods: This was a hospital based cross-sectional prospective comparative study done in Paropakar maternity and Women’s hospital conducted over three month period. Results: During the study period, a total of 126 cases of hypertensive disorders of pregnancy were identified among 3819 obstetric cases. The incidence of hypertensive disorders of pregnancy in this study was 3.3%. Fifty seven of them were found to have serum uric acid level <5.5 mg% (Group A), 43 of them were found to have serum uric acid level ≥5.5mg% (Group B). In those developing hyperuricemia 54.81% had mild hypertension, 40.91% had severe hypertension. Adverse perinatal outcome with serum uric acid level ≥5.5mg/dl had stillbirth in 7%, had low birth weight in 27.9%, 11.6 % were admitted in special care baby unit and 18.6 % had apgar <7 at five minute. Conclusions: Perinatal morbidity and mortality was increased in women with raised uric acid level except admission to special baby care unit Hypertensive disorders of pregnancy are associated with high maternal and perinatal morbidity and mortality. DOI: http://dx.doi.org/10.3126/njog.v9i1.11196 NJOG 2014 Jan-Jun; 2(1):78-81

Sign in / Sign up

Export Citation Format

Share Document