scholarly journals Endometrial Serous Carcinoma Arising from Adenomyosis: A Clinico-Pathological Insight

2021 ◽  
Author(s):  
Amrita Talwar ◽  
Pushpanjali Behera ◽  
Arvind Ahuja ◽  
Bani Sarkar ◽  
Ravi Hari Phulware
Keyword(s):  
Case Report ◽  
Endometrial Carcinoma ◽  
Rare Event ◽  
Abnormal Uterine Bleeding ◽  
Final Diagnosis ◽  
Serous Carcinoma ◽  
Dismal Prognosis ◽  
Endometrial Cavity ◽  
Pubmed Search ◽  
Post Menopausal

Objective: Endometrial cancer (EC) is the most commonly diagnosed malignancy and has the secondhighest mortality rate among gynecological cancers. Adenomyosis is well-known for abnormal uterine bleeding and is a widely reported entity; however, an EC arising from the adenomyosis is a rare event; even rarer is the occurrence of serous endometrial carcinoma. Case report: A 60-year post-menopausal female presented with post-menopausal bleeding. Subsequently, she underwent a hysterectomy, which showed atrophic and cystic endometrium with extensive adenomyosis and atypical endometrial glands, which are diffusely P53 positive with intervening negative benign and focally positive dysplastic endometrial glands. A final diagnosis of serous endometrial carcinoma arising from adenomyosis was rendered. In a table format, previously reported serous endometrial carcinoma Arising cases from adenomyosis using PubMed search had been described. Conclusion: Serous endometrial carcinoma arising from adenomyosis (<20 cases reported) and has a slightly more dismal prognosis than those deriving from the endometrial cavity. Hence, this case report highlights the occurrence, rarity, and importance of such an entity.

scholarly journals Cervical poorly differentiated adenocarcinoma with dominant choriocarcinomatous pattern: A case report

2015 ◽  
Vol 72 (7) ◽  
pp. 651-653 ◽  
Author(s):  
Branka Nikolic ◽  
Aleksandar Curkovic ◽  
Svetlana Dragojevic-Dikic ◽  
Ana Mitrovic ◽  
Igor Kuzmanovic ◽  
...  
Keyword(s):  
Case Report ◽  
Cervical Carcinoma ◽  
Rare Event ◽  
Final Diagnosis ◽  
Good Prognosis ◽  
Cervical Adenocarcinoma ◽  
Preoperative Serum ◽  
Beta Hcg ◽  
Poorly Differentiated ◽  
Proper Diagnosis

Introduction. Gestational trophoblastic neoplasm (GTN), choriocarcinoma in coexistence with primary cervical adenocarcinoma, is a rare event not easy to diagnose. Choriocarcinoma is a malignant form of GTN but curable if metastases do not appear early and spread fast. Case report. We presented choriocarcinoma in coexistence with primary cervical adenocarcinoma in a 48-year-old patient who had radical hysterectomy because of confirmed cervical carcinoma (Dg: Carcinoma porto vaginalis uteri FIGO st I B1). Histological findings confirmed cervical choriocarcinoma with extensive vascular invasion and apoptosis but GTN choriocarcinoma was finally confirmed after immunohystochemical examinations. Preoperative serum human gonadotropine (beta hCG) level stayed unknown. This patient did not have any pregnancy-like symptoms before the operation. The first beta hCG monitoring was done two months after the operation and found negative. According to the final diagnosis the decision of Consilium for Malignant Diseases was that this patient needed serum hCG monitoring as well as treatment with chemotherapy for high-risk GTN and consequent irradiation for adenocarcinoma. Conclusion. The early and proper diagnosis of nonmetastatic choriocarcinoma of nongestational origine in coexistence with cervical carcinoma is curable and can have good prognosis.

Subsequent endometrial carcinoma with adjuvant tamoxifen treatment in Japanese breast cancer patients

2001 ◽  
Vol 11 (4) ◽  
pp. 272-276 ◽  
Author(s):  
N. Nishimura ◽  
T. Hachisuga ◽  
T. Saito ◽  
T. Kawarabayashi
Keyword(s):  
Breast Cancer ◽  
Endometrial Carcinoma ◽  
Cancer Patients ◽  
Myometrial Invasion ◽  
Tamoxifen Treatment ◽  
Adjuvant Tamoxifen ◽  
Serous Carcinoma ◽  
Breast Cancer Patients ◽  
Two Stage ◽  
Endometrial Carcinomas

Abstract.Nishimura N, Hachisuga T, Saito T, Kawarabayashi T. Subsequent endometrial carcinoma with adjuvant tamoxifen treatment in Japanese breast cancer patients.This study aimed to detail the clinicopathologic features of endometrial carcinomas that developed in Japanese patients receiving adjuvant tamoxifen treatment for breast cancer patients. Ten endometrial carcinomas in tamoxifen-treated breast cancer patients were collected from two medical centers. The endometrial carcinomas included two stage Ia, four stage Ib, two stage Ic and two stage IIIc. Three tumors were Grade 1, six were Grade 2, and one was Grade 3. The tumor was limited to the endometrium in two cases. Myometrial invasion was limited to the inner half of the myometrium in five cases and involved the outer half in three. A mild degree of lymphovascular space invasion was identified in five cases. Deep cervical invasion was recognized in one case. The cell types comprised nine endometrioid adenocarcinomas and one serous carcinoma. Five of eight postmenopausal endometrial carcinomas were associated with polypoid endometrial lesions composed of cystically dilated atrophic and proliferative glands widely separated by fibrotic stroma. Two patients with retroperitoneal lymph node metastases died of endometrial cancer. One patient developed a contralateral breast cancer during tamoxifen treatment. No patient died of breast cancer. We did not demonstrate a higher frequency of either high-grade tumors or unfavorable histologic subtypes in tamoxifen-treated Japanese breast cancer patients.

scholarly journals Case Report: Sentinel Lymph Node Mapping of Endometrial Carcinoma Occurring in Uterine Didelphys

2021 ◽  
pp. 100769
Author(s):  
Dib Sassine ◽  
Sara Moufarrij ◽  
Anjelica Hodgson ◽  
Sarah Ehmann ◽  
Nadeem R. Abu-Rustum ◽  
...  
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Endometrial Carcinoma ◽  
Sentinel Lymph Node Mapping ◽  
Lymph Node Mapping

scholarly journals An unusual presentation of acute myocardial infarction in physiotherapy direct access: findings from a case report

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lorenzo Storari ◽  
Valerio Barbari ◽  
Fabrizio Brindisino ◽  
Marco Testa ◽  
Maselli Filippo
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Case Report ◽  
Visceral Pain ◽  
Signs And Symptoms ◽  
Final Diagnosis ◽  
Outpatient Setting ◽  
Direct Access ◽  
Life Threatening ◽  
Medical Referral

Abstract Background Shoulder pain (SP) may originate from both musculoskeletal and visceral conditions. Physiotherapists (PT) may encounter patients with life-threatening pathologies that mimic musculoskeletal pain such as Acute Myocardial Infarction (AMI). A trained PT should be able to distinguish between signs and symptoms of musculoskeletal or visceral origin aimed at performing proper medical referral. Case presentation A 46-y-old male with acute SP lasting from a week was diagnosed with right painful musculoskeletal shoulder syndrome, in two successive examinations by the emergency department physicians. However, after having experienced a shift of the pain on the left side, the patient presented to a PT. The PT recognized the signs and symptoms of visceral pain and referred him to the general practitioner, which identified a cardiac disease. The final diagnosis was acute myocardial infarction. Conclusion This case report highlights the importance of a thorough patient screening examination, especially for patients treated in an outpatient setting, which allow distinguishing between signs and symptoms of musculoskeletal from visceral diseases.

scholarly journals Synovial sarcoma of submandibular gland with aberrant P63 expression a case report of rare event

2019 ◽  
Vol 17 ◽  
pp. 200314
Author(s):  
Afnan Elsayed ◽  
Haneen Al-Maghrabi ◽  
Hosam Alardati ◽  
Ameen Alherabi ◽  
Abdelrazak Meliti
Keyword(s):  
Case Report ◽  
Submandibular Gland ◽  
Synovial Sarcoma ◽  
Rare Event
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