scholarly journals Macular Optical Coherence Tomography Imaging in Glaucoma

2021 ◽  
Author(s):  
Alireza Kamalipour ◽  
Sasan Moghimi
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Structural Changes ◽  
Posterior Segment ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Tomography Imaging ◽  
Optical Coherence Tomography Imaging ◽  
Peripapillary Area

The advent of spectral-domain optical coherence tomography has played a transformative role in posterior segment imaging of the eye. Traditionally, images of the optic nerve head and the peripapillary area have been used to evaluate the structural changes associated with glaucoma. Recently, there is growing evidence in the literature supporting the use of macular spectral-domain optical coherence tomography as a complementary tool for clinical evaluation and research purposes in glaucoma.

Comparison of Spectral Domain Optical Coherence Tomography and Color Photographic Imaging of the Optic Nerve Head in Management of Glaucoma

2009 ◽  
Vol 40 (3) ◽  
pp. 255-263 ◽  
Author(s):  
Yuriko Kotera ◽  
Yoshiaki Yasuno ◽  
Masanori Hangai ◽  
Ryo Inoue ◽  
Shuichi Makita ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Spectral Domain ◽  
Optical Coherence

scholarly journals Longitudinal assessment of optic nerve head changes using optical coherence tomography in a primate microbead model of ocular hypertension

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Anita S. Y. Chan ◽  
Tin Aung Tun ◽  
John C. Allen ◽  
Myoe Naing Lynn ◽  
Sai Bo Bo Tun ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Ocular Hypertension ◽  
Optic Nerve Head ◽  
Structural Damage ◽  
Structural Changes ◽  
Lamina Cribrosa ◽  
Optical Coherence ◽  
Longitudinal Assessment ◽  
The Mean

Abstract In humans, the longitudinal characterisation of early optic nerve head (ONH) damage in ocular hypertension (OHT) is difficult as patients with glaucoma usually have structural ONH damage at the time of diagnosis. Previous studies assessed glaucomatous ONH cupping by measuring the anterior lamina cribrosa depth (LCD) and minimal rim width (MRW) using optical coherence tomography (OCT). In this study, we induced OHT by repeated intracameral microbead injections in 16 cynomolgus primates (10 unilateral; 6 bilateral) and assessed the structural changes of the ONH longitudinally to observe early changes. Elevated intraocular pressure (IOP) in OHT eyes was maintained for 7 months and serial OCT measurements were performed during this period. The mean IOP was significantly elevated in OHT eyes when compared to baseline and compared to the control eyes. Thinner MRW and deeper LCD values from baseline were observed in OHT eyes with the greatest changes seen between month 1 and month 2 of OHT. Both the mean and maximum IOP values were significant predictors of MRW and LCD changes, although the maximum IOP was a slightly better predictor. We believe that this model could be useful to study IOP-induced early ONH structural damage which is important for understanding glaucoma pathogenesis.

Sign in / Sign up

Export Citation Format

Share Document