Plasma TLR2 and IGF2/H19 imprinting control region gene methylation in fetal growth restriction

Objective of the study: Comprehensive assessment of risk factors, the implementation of which leads to FGR with early and late manifestation. To evaluate the results of the first prenatal screening: PAPP-A, B-hCG, made at 11-13 weeks. Materials and Methods: A retrospective study included 110 pregnant women. There were 48 pregnant women with early manifestation of fetal growth restriction, 62 pregnant women with late manifestation among them. Results of the study: The risk factors for the formation of the FGR are established. Statistically significant differences in the indicators between groups were not established in the analyses of structures of extragenital pathology. According to I prenatal screening, there were no statistical differences in levels (PAPP-A, b-hCG) in the early and late form of FGR.

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Sleep Apnea and Fetal Growth Restriction

Case Medical Research ◽

10.31525/ct1-nct04084990 ◽

2019 ◽

Author(s):

Keyword(s):

Sleep Apnea ◽

Fetal Growth ◽

Fetal Growth Restriction ◽

Growth Restriction

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Pathogenetic mechanisms and basic approaches to Doppler diagnostics of prenatal centralization of blood circulation in fetal growth restriction syndrome

Practical medicine ◽

10.32000/2072-1757-2020-2-21-27 ◽

2020 ◽

Vol 18 (2) ◽

pp. 21-27

Author(s):

Yu. A. STEPANOVA ◽

◽

V. I. SEMINA ◽

Keyword(s):

Fetal Growth ◽

Fetal Growth Restriction ◽

Blood Circulation ◽

Growth Restriction ◽

Pathogenetic Mechanisms ◽

Basic Approaches

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INTRAUTERINE GROWTH RETARDATION - A REVIEW ARTICLE

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2018.6.25a ◽

2018 ◽

pp. 184-195

Author(s):

Minh Son Pham ◽

Vu Quoc Huy Nguyen ◽

Dinh Vinh Tran

Keyword(s):

Fetal Growth ◽

Gestational Age ◽

Small For Gestational Age ◽

Fetal Growth Restriction ◽

Growth Restriction ◽

Growth Potential ◽

National Guidelines ◽

Intrauterine Growth ◽

No Gold Standard

Small for gestational age (SGA) and fetal growth restriction (FGR) is difficult to define exactly. In this pregnancy condition, the fetus does not reach its biological growth potential as a consequence of impaired placental function, which may be because of a variety of factors. Fetuses with FGR are at risk for perinatal morbidity and mortality, and poor long-term health outcomes, such as impaired neurological and cognitive development, and cardiovascular and endocrine diseases in adulthood. At present no gold standard for the diagnosis of SGA/FGR exists. The first aim of this review is to: summarize areas of consensus and controversy between recently published national guidelines on small for gestational age or fetal growth restriction; highlight any recent evidence that should be incorporated into existing guidelines. Another aim to summary a number of interventions which are being developed or coming through to clinical trial in an attempt to improve fetal growth in placental insufficiency. Key words: fetal growth restriction (FGR), Small for gestational age (SGA)

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The secrets of placental mosaicism: clinical observation of the full form of confined placental trisomy 22 and literature review

10.21516/2413-1458-2020-19-1-35-40 ◽

2020 ◽

Author(s):

I.V. Komarova, A.A. Nikiforenko, A.V. Fedunyak

Keyword(s):

Prenatal Diagnosis ◽

Literature Review ◽

Fetal Growth ◽

Fetal Growth Restriction ◽

Clinical Observation ◽

Growth Restriction ◽

Favorable Outcome ◽

Full Form ◽

Placental Mosaicism ◽

In Pregnancy

Literature reports of placental mosaicism, including trisomy 22, were analyzed. The chance of correlation of placental aneuploidy with fetus aneuploidy, also the probability of complications in pregnancy and fetal growth restriction and postnatal patients growth in the cases of confined placental mosaicism, were demonstrated. The case of prenatal diagnosis of confined placental mosaicism of trisomy 22 with favorable outcome is presented. The necessity of cytogenic assay of amniocytes and fetal lymphocytes in the case of placental heteroploidy diagnosis was emphasized.

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