Research objective. To identify clinico-laboratorial and urodynamic deviations among children with overactive bladder.
Materials and methods. The study is based on examination of 20 somatically healthy children of 7-10 years old with the following complaints: sudden irresistible urges to urinate, that could be hardly restrained with or without imperative urge incontinence; frequent urination in small portions during the day; frequent awakenings during the night due to the emerging urge to urinate and involuntary urination at night. All children have been examined clinically (identification of the level of homocysteine, registration of the rhythm of urination (by keeping a diary of urination)) and through instrumental methods: uroflowmetry, ultrasound examination of the bladder with identification of the volume of residual urine, electroencephalography.
Results. After the examination, the following abnormalities were identified among the majority of the patients: hyperhomocysteinemia; registration of the rhythm of urination showed that the predominant type was pollakiuria, which might be observed in frequent (more than 8 times a day) urination in small portions (among 60% of children), also enuresis (among 65%) and daytime urinary incontinence in the one third of the patients (30%) were diagnosed. On the basis of ultrasound examination of the bladder, it could be concluded that the one third of the children (33%) had an increase in the volume of residual urine (due to a decrease in the contractile function of the detrusor). By the uroflow method of research it was found out that among almost the half of the children (45%), the intermittent type of urination prevailed (in which the maximum and average urine flow rate was reduced, the time to reach the maximum speed was shortened), also rapid (30%) and non-obstructive (25%) types were diagnosed. According to the electroencephalography data, disorganization of the alpha rhythm, with a tendency to an increase in the number of beta rhythm waves was found.