scholarly journals Association between single nucleotide polymorphisms in the TSPYL6 gene and breast cancer susceptibility in the Han Chinese population

Oncotarget ◽  
2016 ◽  
Vol 7 (34) ◽  
pp. 54771-54781 ◽  
Author(s):  
Ming Liu ◽  
Bin Li ◽  
Wen Guo ◽  
Xiyang Zhang ◽  
Zhengshuai Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Single Nucleotide Polymorphisms ◽  
Chinese Population ◽  
Cancer Susceptibility ◽  
Breast Cancer Susceptibility ◽  
Han Chinese ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Han Chinese Population

scholarly journals Single nucleotide polymorphisms at the TRAF1/C5 locus are associated with rheumatoid arthritis in a Han Chinese population

2011 ◽  
Vol 12 (1) ◽  
Author(s):  
Jing Zhu ◽  
Dinging Zhang ◽  
Fengxia Wu ◽  
Fei He ◽  
Xiaoqi Liu ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Single Nucleotide Polymorphisms ◽  
Chinese Population ◽  
Han Chinese ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Han Chinese Population

scholarly journals The Associations of Single Nucleotide Polymorphisms in miR-146a, miR-196a and miR-499 with Breast Cancer Susceptibility

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e70656 ◽  
Author(s):  
Ping-Yu Wang ◽  
Zong-Hua Gao ◽  
Zhong-Hua Jiang ◽  
Xin-Xin Li ◽  
Bao-Fa Jiang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Single Nucleotide Polymorphisms ◽  
Cancer Susceptibility ◽  
Breast Cancer Susceptibility ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

Association Analysis of Single-Nucleotide Polymorphisms of USP24 and USP40 with Parkinson’s Disease in the Han Chinese Population

2012 ◽  
Vol 68 (3) ◽  
pp. 181-184 ◽  
Author(s):  
Bi Zhao ◽  
Wei Song ◽  
Yong Ping Chen ◽  
Rui Huang ◽  
Ke Chen ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Association Analysis ◽  
Chinese Population ◽  
Han Chinese ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Han Chinese Population

scholarly journals Single nucleotide polymorphisms in the FAM167A-BLK gene are associated with polymyositis/dermatomyositis in the Han Chinese population

2015 ◽  
Vol 62 (2) ◽  
pp. 153-162 ◽  
Author(s):  
Si Chen ◽  
Wei Wu ◽  
Jing Li ◽  
Qian Wang ◽  
Yuan Li ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Chinese Population ◽  
Han Chinese ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Han Chinese Population

scholarly journals Genetic Variants in the Promoter Region of miR-10b and the Risk of Breast Cancer

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Jiaping Chen ◽  
Yue Jiang ◽  
Jing Zhou ◽  
Sijun Liu ◽  
Yayun Gu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Single Nucleotide Polymorphisms ◽  
In Silico ◽  
Promoter Region ◽  
Cancer Susceptibility ◽  
Chinese Women ◽  
Close Association ◽  
Breast Cancer Susceptibility ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

Variants in microRNA genes may affect their expression by interfering with the microRNA maturation process and may substantially contribute to the risk of breast cancer. Recent studies have identified miR-10b as an interesting candidate because of its close association with the metastatic behavior of breast cancer. However, the roles of miR-10b-related single nucleotide polymorphisms in breast cancer susceptibility remain unclear. This case-control study evaluated the associations between variants in the upstream transcription regulation region of miR-10b and the risk of breast cancer among Chinese women. Seven potentially functional SNPs were investigated using genotyping assays. The potential biological functions of the identified positive SNPs were further evaluated using in silico databases. We found that rs4078756, which was located at the promoter region of miR-10b, was significantly associated with breast cancer risk (rs4078756 AG/GG versus AA, adjusted odds ratio: 1.17, 95% confidence interval: 1.02–1.35). The other six single nucleotide polymorphisms exhibited negative associations. Based on the in silico prediction, rs4078756 potentially regulated miR-10b expression through promoter activation or repression. These findings indicate that a potentially functional SNP (rs4078756) in the promoter region of miR-10b may contribute to breast cancer susceptibility among Chinese women.

scholarly journals Breast Cancer Association Studies in a Han Chinese Population using 10 European-ancestry-associated Breast Cancer Susceptibility SNPs

2014 ◽  
Vol 15 (1) ◽  
pp. 85-91 ◽  
Author(s):  
Yan-Ping Guan ◽  
Xue-Xi Yang ◽  
Guang-Yu Yao ◽  
Fei Qiu ◽  
Jun Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Chinese Population ◽  
Cancer Susceptibility ◽  
Association Studies ◽  
Breast Cancer Susceptibility ◽  
Han Chinese ◽  
European Ancestry ◽  
Han Chinese Population

Analysis of the genotype of diacylglycerol kinase delta single-nucleotide polymorphisms in Parkinson disease in the Han Chinese population

2012 ◽  
Vol 60 (1) ◽  
pp. 82
Author(s):  
Hui-Fang Shang ◽  
Wei Song ◽  
YongPing Chen ◽  
Rui Huang ◽  
Ke Chen ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Parkinson Disease ◽  
Chinese Population ◽  
Diacylglycerol Kinase ◽  
Han Chinese ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Han Chinese Population

scholarly journals Association of Single Nucleotide Polymorphisms in TCF2 with Type 2 Diabetes Susceptibility in a Han Chinese Population

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e52938 ◽  
Author(s):  
Xuelong Zhang ◽  
Hong Qiao ◽  
Yanling Zhao ◽  
Xi Wang ◽  
Haiming Sun ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Single Nucleotide Polymorphisms ◽  
Chinese Population ◽  
Han Chinese ◽  
Nucleotide Polymorphisms ◽  
Diabetes Susceptibility ◽  
Single Nucleotide ◽  
Han Chinese Population
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