scholarly journals Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells

Oncotarget ◽  
2016 ◽  
Vol 7 (13) ◽  
pp. 16663-16675 ◽  
Author(s):  
Melissa McNaughton ◽  
Melissa Pitman ◽  
Stuart M. Pitson ◽  
Nigel J. Pyne ◽  
Susan Pyne
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Kinase Inhibitors ◽  
Growth Arrest ◽  
Sphingosine Kinase ◽  
Proteasomal Degradation ◽  
Sphingosine Kinase 1 ◽  
Prostate Cancer Cells ◽  
Dihydroceramide Desaturase ◽  
Androgen Independent

scholarly journals Immunosuppressive drug FTY720 sensitizes prostate cancer cells to radiotherapy by inhibition of sphingosine kinase‐1.

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Dmitry Pshezhetskiy ◽  
Torsten Bohler ◽  
Nicolas Doumerc ◽  
Muriel Golzio ◽  
Volker Brinkmann ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Sphingosine Kinase ◽  
Immunosuppressive Drug ◽  
Sphingosine Kinase 1 ◽  
Prostate Cancer Cells

Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cells

2011 ◽  
Vol 51 (1) ◽  
pp. 87-93 ◽  
Author(s):  
Sung-Yun Cho ◽  
Hyo-Jeong Lee ◽  
Soo-Jin Jeong ◽  
Hyo-Jung Lee ◽  
Hyun-Seok Kim ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Sphingosine Kinase ◽  
Sphingosine Kinase 1 ◽  
Prostate Cancer Cells

scholarly journals The Roles of Sphingosine Kinase 1 and 2 in Regulating the Metabolome and Survival of Prostate Cancer Cells

Biomolecules ◽  
2013 ◽  
Vol 3 (4) ◽  
pp. 316-333 ◽  
Author(s):  
Francesca Tonelli ◽  
Manal Alossaimi ◽  
Viswanathan Natarajan ◽  
Irina Gorshkova ◽  
Evgeny Berdyshev ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Sphingosine Kinase ◽  
Sphingosine Kinase 1 ◽  
Prostate Cancer Cells

scholarly journals Activation of the orphan nuclear receptor ROR? induces growth arrest in androgen-independent DU 145 prostate cancer cells

The Prostate ◽  
2001 ◽  
Vol 46 (4) ◽  
pp. 327-335 ◽  
Author(s):  
Roberta M. Moretti ◽  
Marina Montagnani Marelli ◽  
Marcella Motta ◽  
Donatella Polizzi ◽  
Silvia Monestiroli ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Nuclear Receptor ◽  
Growth Arrest ◽  
Orphan Nuclear Receptor ◽  
Prostate Cancer Cells ◽  
Androgen Independent

Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells

2006 ◽  
Vol 72 (4) ◽  
pp. 427-436 ◽  
Author(s):  
Shlomit Erlich ◽  
Pazit Tal-Or ◽  
Ronit Liebling ◽  
Roy Blum ◽  
Devarajan Karunagaran ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Growth Arrest ◽  
Prostate Cancer Cells ◽  
Ras Inhibition ◽  
Androgen Independent

scholarly journals FTY720 (Fingolimod) Sensitizes Prostate Cancer Cells to Radiotherapy by Inhibition of Sphingosine Kinase-1

2010 ◽  
Vol 70 (21) ◽  
pp. 8651-8661 ◽  
Author(s):  
Dmitri Pchejetski ◽  
Torsten Bohler ◽  
Leyre Brizuela ◽  
Lysann Sauer ◽  
Nicolas Doumerc ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Sphingosine Kinase ◽  
Sphingosine Kinase 1 ◽  
Prostate Cancer Cells

scholarly journals Everolimus (RAD001) sensitizes prostate cancer cells to docetaxel by down-regulation of HIF-1α and sphingosine kinase 1

Oncotarget ◽  
2016 ◽  
Vol 7 (49) ◽  
pp. 80943-80956 ◽  
Author(s):  
Heba Alshaker ◽  
Qi Wang ◽  
Yoshiaki Kawano ◽  
Tawfiq Arafat ◽  
Torsten Böhler ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Sphingosine Kinase ◽  
Sphingosine Kinase 1 ◽  
Prostate Cancer Cells ◽  
Down Regulation
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