A Comparative Analysis of Bone Formation Induced by Human Demineralized Freeze-Dried Bone and Enamel Matrix Derivative in Rat Calvaria Critical-Size Bone Defects

2008 ◽  
Vol 79 (7) ◽  
pp. 1217-1224 ◽  
Author(s):  
Giuseppe Intini ◽  
Sebastiano Andreana ◽  
Robert J. Buhite ◽  
Libuse A. Bobek
Keyword(s):  
Comparative Analysis ◽  
Bone Formation ◽  
Critical Size ◽  
Bone Defects ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Rat Calvaria ◽  
Freeze Dried ◽  
Matrix Derivative

Porcine Fetal Enamel Matrix Derivative Enhances Bone Formation Induced by Demineralized Freeze Dried Bone Allograft In Vivo

2000 ◽  
Vol 71 (8) ◽  
pp. 1278-1286 ◽  
Author(s):  
B.D. Boyan ◽  
T.C. Weesner ◽  
C.H. Lohmann ◽  
D. Andreacchio ◽  
D.L. Carnes ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Allograft ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Freeze Dried ◽  
Matrix Derivative

Effect of Enamel Matrix Derivative (Emdogain) on Bone Defects in Rabbit Tibias

2004 ◽  
Vol 30 (2) ◽  
pp. 69-73 ◽  
Author(s):  
Roberto Cornelini ◽  
Antonio Scarano ◽  
Maurizio Piattelli ◽  
Sebastiano Andreana ◽  
Ugo Covani ◽  
...  
Keyword(s):  
Test Group ◽  
Inflammatory Cells ◽  
Bone Defects ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
The Right ◽  
Observation Times ◽  
Microscopy Examination ◽  
Observation Period ◽  
Matrix Derivative

Abstract The aim of this study was to assess the effect of an enamel matrix derivative (Emdogain, Biora, AB, Malmö, Sweden) on bone healing. Ten New Zealand rabbits, weighing about 2.5 kg, were used. One 8-mm bone defect was created in each tibia. The defect on the right leg was filled with Emdogain, whereas the defect on the opposite leg was left unfilled as control. A total of 20 defects were created. Five rabbits each were killed at 4 and 8 weeks with an overdose of Tanax. Block sections containing the defects were retrieved and the specimens processed for light microscopy examination. The slides were stained with acid and basic fuchsin and toluidine blue. Histologically, no differences were noted in both groups at each observation period; in the test group, remnants of the implanted Emdogain were not present at 4 weeks. Newly formed bone was detectable in both groups at all observation times. At 8 weeks, both groups showed mature bone, and in the test group the material implanted was not visible. No inflammatory cells were visible in both groups. In conclusion, our results indicate that Emdogain implanted in bone defects is fully resorbed after 4 to 8 weeks and does not adversely affect bone formation.

scholarly journals The Effect of Enamel Matrix Derivative (Emdogain®) on Bone Formation: A Systematic Review

2009 ◽  
Vol 15 (3) ◽  
pp. 215-224 ◽  
Author(s):  
Florian Rathe ◽  
Rüdiger Junker ◽  
Betsy M. Chesnutt ◽  
John A. Jansen
Keyword(s):  
Systematic Review ◽  
Bone Formation ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Matrix Derivative

In Vitro Evaluation of Demineralized Freeze-Dried Bone Allograft in Combination With Enamel Matrix Derivative

2013 ◽  
pp. 1-9 ◽  
Author(s):  
Richard J. Miron ◽  
Dieter Bosshardt ◽  
Oliver Laugisch ◽  
Michel Dard ◽  
Anja C. Gemperli ◽  
...  
Keyword(s):  
Bone Allograft ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
In Vitro Evaluation ◽  
Freeze Dried ◽  
Matrix Derivative
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