Hemorrhoidectomy: Per- and Post-Operative Pain Status and Patient Comfort After the Administration of Two Different Techniques

Bromfenac ophthalmic solution 0.09 % (BROMDAY™, ISTA Pharmaceuticals, Inc., Irvine, CA) is the first and only once-daily topical ophthalmic non-steroidal anti-inflammatory drug (NSAID) approved by the Food and Drug Administration for the treatment of post-operative pain and inflammation following cataract surgery. Topical NSAIDs are important following surgery to enhance patient comfort and limit inflammation, which may otherwise restrict visual rehabilitation. In a recently published study looking at Early Treatment Diabetic Retinopathy Study (ETDRS) acuities and macular optical computed tomographies (OCTs) in the post-operative period, bromfenac had lower post-operative macular volumes and retinal thicknesses compared with nepafenac, which correlated with a separate retrospective study that found fewer clinical cases of cystoid macular edema (CME) following uneventful phacoemulsification. Since regulatory approval in Japan (2000) and the US (2005 and 2010), bromfenac has been shown to be a safe and effective medication, with more than 26 million ophthalmic uses. Once-daily dosing may confer improvements in compliance and reduce exposure to preservatives, which have been shown to lead to corneal toxicity.

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Analgesic Effects of Pre-induction Low-dose Ketamine on Post-tonsillectomy Patients

Journal of Enam Medical College ◽

10.3329/jemc.v8i2.36729 ◽

2018 ◽

Vol 8 (2) ◽

pp. 74-79

Author(s):

Muhammad Delwar Hussain ◽

Md Torab Mallick ◽

Mohammad Kamal Hossain

Keyword(s):

Pain Intensity ◽

General Anaesthesia ◽

Analgesic Effect ◽

Low Dose ◽

Demographic Data ◽

Operation Time ◽

Patient Comfort ◽

Military Hospital ◽

Control Group ◽

Post Operative Pain

Background: Post-operative pain management aims to decrease pain intensity with patient comfort and to improve post-operative outcome. Multimodal analgesia is currently recommended for effective post-operative pain control with lower total doses of analgesics and fewer side effects.Objective: To compare the analgesic effect of pre-induction low-dose ketamine against conventional general anaesthesia.Materials and Methods: This prospective comparative study was conducted over a period of 12 months at Combined Military Hospital, Dhaka. Two hundred and forty patients of either sex requiring tonsillectomy were divided into two groups: conventional general anaesthesia (control group) and general anaesthesia with low-dose ketamine (ketamine group). Non-invasive blood pressure, heart rate and SpO2 were recorded at regular intervals throughout the anaesthetic period. Post-operative analgesia was provided for both the groups using pethidine intramuscularly. Time to complete operation, pain intensity, time to request for first analgesia were noted and total opioid consumption and complications, if any occurred in 24 hours post-operatively, were also recorded and addressed accordingly.Results: The demographic data and mean operation time were similar in both the groups (p>0.05).Time to request for first analgesia was longer in lowdose ketamine group (mean ± SD 5.36±3.21 hours) than in control group (mean ± SD 2.49±1.53 hours) (p<0.05). Total dosage of pethidine consumption over 24 hours period was less in ketamine group with satisfactory pain relief (mean ± SD 98.73±2.60 mg) than in control group (mean ± SD 142.52±3.48 mg) (p<0.05). Post-operative complications were also less in ketamine group than control group (p<0.05).Conclusion: The result of this study suggests that pre-induction low-dose ketamine has pre-emptive analgesic effect and reduces overall post-operative opioid requirements.J Enam Med Col 2018; 8(2): 74-79

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Post-Operative Pain Comparison between Peri-Operative Bupivacaine Infiltration Vs Post-Operative Opioids Analgesics in Patient Undergoing Abdominal Surgery in First 6 Hours

The International Journal of Frontier Sciences ◽

10.37978/tijfs.v2i2.39 ◽

2018 ◽

Vol 2 (2) ◽

pp. 26-32

Author(s):

Syeda Hina Zahra ◽

Qudrat Ullah ◽

Usman Ali Rehman ◽

Asif Hanif ◽

Sami Ullah Bhatti

Keyword(s):

Pain Management ◽

Abdominal Surgery ◽

Female Gender ◽

Pain Scale ◽

Patient Comfort ◽

P Value ◽

Moderate Pain ◽

Wound Infiltration ◽

Surgical Department ◽

Post Operative Pain

Abstract:Background: To compare between opioids and wound infiltration to reduce post-operative painin abdominal surgery in first 6 hours, in appropriate treatment, contraindications of treatment and increase mortality of patients. This article presents novel approach to surgical site infiltration techniques and intravenous opioids for abdominal surgery to reduce pain. The main aim of this study is optimal patient comfort rather than reduce pain intensity, reduction offside effects is also an important goal in pain management.Methodology: Data was collected from surgical department of Gulab Devi Chest Hospital. Duringabdominal surgery bupivacaine was given to some patients while other were managed by postoperative opioids and by using designed performa it is concluded that which one of them is better method for post-operative pain management.Results: This is the descriptive study conducted in Gulab Devi Hospital Lahore.in this study, inthis study minimum age of the patients was 14 and maximum age of the patients was 80. The mean age was 32.16+12.32 years. In this study out of total 100 patients, 18(18.00%) were male patients and 82(82.00%) were females. Female gender predominated in this study. in this study, p-value is 0.00 (<0.05%) so pain relieving chances of bupivacaine infiltration as moderate pain scale were 84% and in distracting pain scale chances in bupivacaine infiltration were 16%.But pain relieving chances of opioids as moderate pain scale were 12.24 % and in distracting pain scale chances in opioids were 87.75%.so peri-operative pain management by bupivacaine infiltration is better than post –operative opioids management in patients undergoing abdominal surgery.Conclusion: According to my research bupivacaine wound infiltration is better method for postoperative pain management in abdominal surgeries. Our study was conducted at Gulab DeviHospital and Services Hospital in an area of pain management by opioids and infiltration, whichmay limit the applications of our findings in area of pain management by opioids and infiltrationprevalence.

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An evaluation of merocel and neosporin impregnated ribbon gauze packs in patients following nasal surgery: a prospective randomised trial

Health Renaissance ◽

10.3126/hren.v10i1.6004 ◽

1970 ◽

Vol 10 (1) ◽

pp. 30-34 ◽

Cited By ~ 2

Author(s):

RR Joshi ◽

A Nepal ◽

S Thapa Chhetri ◽

S Bhandary ◽

TB Panta ◽

...

Keyword(s):

Pain Score ◽

Polyvinyl Acetate ◽

Randomised Trial ◽

Visual Analog Score ◽

Patient Comfort ◽

Nasal Surgery ◽

Prospective Randomised Trial ◽

Post Operative Pain ◽

The Mean

Background: Packs are placed following nasal surgeries to arrest haemorrhage, to prevent septal haematoma and synechie formation. Despite Merocel, a tampon constructed from a foam polymer of hydroxylated polyvinyl acetate, which is less abrasive and hence associated with the less pain, we still use Neosporine Impregnated Ribbon Gauze (NIRG). Objective: To compare Merocel and the Neosporine Impregnated Ribbon gauze (NIRG) packs in regards to the post-operative pain levels caused by them and their ability to prevent haemorrhage, crusting and synechie. Methods: The nose was packed after surgery either with the Merocel pack or Neosporin Impregnated Ribbon Gauze (NIRG) according to the randomisation. The pain score was noted on the Visual analog score while packs were in situ and again immediately after the pack removal. The haemorrhage, crusting and synechie were noted if present. Results: Among 106 patients, 61 were male and 45 were female. In Merocel group there were 51 patients and in NIRG group 55. The mean pain score for merocel was 4.15 while in situ and 3.66 immediately after removal where as mean pain score for NIRG was 6 while in situ and 3.78 immediately after removals. Post-operative crusting and synechie were seen relatively more in NIRG pack group. Conclusion: Merocel is superior in terms of both patient comfort and pain. DOI: http://dx.doi.org/10.3126/hren.v10i1.6004 HREN 2012; 10(1): 30-34

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Degradable polymeric vehicles for postoperative pain management

Nature Communications ◽

10.1038/s41467-021-21438-3 ◽

2021 ◽

Vol 12 (1) ◽

Author(s):

Natasha C. Brigham ◽

Ru-Rong Ji ◽

Matthew L. Becker

Keyword(s):

Pain Management ◽

Extended Release ◽

Postoperative Pain Management ◽

Patient Comfort ◽

Effective Control ◽

Prescription Opioids ◽

Polymeric Systems ◽

Post Operative Pain ◽

Review Current

AbstractEffective control of pain management has the potential to significantly decrease the need for prescription opioids following a surgical procedure. While extended release products for pain management are available commercially, the implementation of a device that safely and reliably provides extended analgesia and is sufficiently flexible to facilitate a diverse array of release profiles would serve to advance patient comfort, quality of care and compliance following surgical procedures. Herein, we review current polymeric systems that could be utilized in new, controlled post-operative pain management devices and highlight where opportunities for improvement exist.

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