scholarly journals Comparison of Primary Tumor SUVmax Between Small Cell Lung Cancer and Non-Small Cell Lung Cancer

2019 ◽  
Vol 2 (5) ◽  
Author(s):  
Huynh Quang Huy
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Primary Tumor ◽  
Small Cell ◽  
Small Cell Lung

Analysis of primary tumor metabolic volume during chemoradiotherapy in locally advanced non-small cell lung cancer

2017 ◽  
Vol 194 (2) ◽  
pp. 107-115 ◽  
Author(s):  
Olarn Roengvoraphoj ◽  
Cherylina Wijaya ◽  
Chukwuka Eze ◽  
Minglun Li ◽  
Maurice Dantes ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Primary Tumor ◽  
Locally Advanced ◽  
Small Cell ◽  
Small Cell Lung ◽  
Metabolic Volume

scholarly journals OTHR-07. Systematic Review and Meta-analysis of Lung Cancer Brain Metastasis and Primary Tumor PD-L1 Expression Discordance

2021 ◽  
Vol 3 (Supplement_3) ◽  
pp. iii15-iii16
Author(s):  
Raees Tonse ◽  
Muni Rubens ◽  
Haley Appel ◽  
Martin C Tom ◽  
Matthew D Hall ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Systematic Review ◽  
Brain Metastasis ◽  
Tumor Cell ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Primary Tumor ◽  
Small Cell ◽  
Receptor Expression ◽  
Small Cell Lung

Abstract Background Novel immunotherapeutic strategies, such as those targeting the PD-1/PD-L1 axis, are promising in patients with metastatic lung cancer and are often administered when tumors show PD-L1 positivity. The objective of this study was to analyze PD-L1 receptor discordance in tumor cell between the primary tumor and lung cancer brain metastasis (LCBM). Methods A systematic review of series published prior to April 2021 obtained from the Medline database of biopsied or resected LCBM evaluating PD-L1 discordance was performed using PRISMA guidelines. Weighted random effects models were used to calculate pooled estimates. Results Six full-text articles (n=247 patients) with a median of 32 patients in each study (range: 24–73 patients) reported PD-L1 receptor expression analyses of both primary lung tumors and brain metastases. The majority of patients (81%) were smokers, with 67% non-small cell lung cancer and 33% small cell lung cancer. The pooled estimate for overall PD-LI receptor concordance between primary and LCBM was 76% (95% CI: 52%-90). The positivity rate varied when analyzed by various cutoff levels of PD-L1 expression; for <1% expression, it was 41% (95% CI: 22%-62%) for primary vs. 58% (95% CI: 35%-78%) for LCBM; for PD-L1 expression of 1–50%, it was 24% (95% CI: 13%-40%) vs. 19% (95% CI: 10%-33%); and for PD-L1 >50% it was 12% (95% CI: 4%-33%) vs. 21% (95% CI: 14%-29%) (p=0.425). The pooled estimate for overall PD-LI receptor discordance between primary and LCBM was 17% (95% CI: 10%-27%). Meta-regression analysis showed that age, sex, smoking status, and histology were not associated with PD-LI receptor discordance. Conclusions PD-L1 status discordance in tumor cell occurs in approximately 20% of LCBM, with the greatest discordance in the <1% expression category. Awareness of this discordance is important for the selection of immune checkpoint inhibitor therapy as well as in the analysis of patterns of failures.

Comparison of prognostic values of primary tumor and nodal 18F-fluorodeoxyglucose uptake in non-small cell lung cancer with N1 disease

2019 ◽  
Vol 29 (10) ◽  
pp. 5288-5297
Author(s):  
Chae Hong Lim ◽  
Seung Hyup Hyun ◽  
Seung Hwan Moon ◽  
Young Seok Cho ◽  
Joon Young Choi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Primary Tumor ◽  
Small Cell ◽  
Small Cell Lung ◽  
18F Fluorodeoxyglucose

scholarly journals Retrospective study of efficacy of adjuvant chemotherapy using tegafur-uracil in patients with non-small cell lung cancer with primary tumor size of 4.1–5.0 cm

2019 ◽  
Vol 11 (7) ◽  
pp. 3103-3111
Author(s):  
Hiroyuki Adachi ◽  
Teppei Nishii ◽  
Taketsugu Yamamoto ◽  
Takuya Nagashima ◽  
Yoshihiro Ishikawa ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Retrospective Study ◽  
Adjuvant Chemotherapy ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Tumor Size ◽  
Primary Tumor ◽  
Small Cell ◽  
Small Cell Lung ◽  
Primary Tumor Size

Abstract 1726: Evaluation of PD-L1/PD-1 on circulating tumor cells (CTCs) and on primary tumor in advanced non-small cell lung cancer (NSCLC)

2017 ◽  
Author(s):  
Galaktea Kallergi ◽  
Eleni Kyriaki Vetsika ◽  
Despoina Aggouraki ◽  
Eleni Lagoudaki ◽  
Anastasios Koutsopoulos ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Cell Lung Cancer ◽  
Primary Tumor ◽  
Small Cell ◽  
Small Cell Lung

Aggressive Treatment of Primary Tumor in Patients With Non–Small-Cell Lung Cancer and Exclusively Brain Metastases

2013 ◽  
Vol 14 (1) ◽  
pp. 6-13 ◽  
Author(s):  
Cynthia Villarreal-Garza ◽  
Dolores de la Mata ◽  
Diego G. Zavala ◽  
Eleazar O. Macedo-Perez ◽  
Oscar Arrieta
Keyword(s):  
Lung Cancer ◽  
Brain Metastases ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Primary Tumor ◽  
Small Cell ◽  
Aggressive Treatment ◽  
Small Cell Lung
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