scholarly journals INDICATORS OF COGNITIVE FUNCTIONS IN THE EARLY POSTOPERATIVE PERIOD AFTER APPLICATION OF EXTRA-INTRACRANIAL MICROSURGICAL ANASTOMOSES AT OCCLUSIVE-STENOTIC LESION IN THE INTERNAL CAROTID ARTERY

2017 ◽  
pp. 26-34
Author(s):  
I.Y. Berezina ◽  
L.I. Sumsky
2021 ◽  
Vol 9 (3) ◽  
pp. 415-424
Author(s):  
V.A. Panfilov ◽  
◽  
A.O. Virganskiy ◽  
K.V. Romanenko ◽  
◽  
...  

BACKGROUND: Eversion carotid endarterectomy is one of the most frequently used methods of carotid endarterectomy. This is primarily due to the relative ease of surgical techniques, reduction in the risk of hemodynamic disorders in the reconstruction zone and the absence of the need to use synthetic material. The main disadvantage of eversion carotid endarterectomy is poor visualization of the distal edge of the atherosclerotic plaque and the lack of control of the unfixed edge of intima in common atherosclerotic lesion of the internal carotid artery. The use of a modified technique of eversion carotid endarterectomy avoids these disadvantages and preserves its advantages. AIM: to analyze the results of the use of modified eversion carotid endarterectomy in patients with extended disease to the internal carotid artery. MATERIALS AND METHODS: The study is based on the analysis of the results of treatment of patients with chronic cerebrovascular insufficiency due to extended atherosclerotic disease of the internal carotid artery, in whom eversion carotid endarterectomy was performed using a modified technique in the conditions of the Department of Vascular Surgery in Vinogradov City Hospital. The presence of an atherosclerotic plaque extending over a distance of more than 2.5 cm from the bifurcation was considered a common damage to the internal carotid artery. The assessment of intraoperative parameters, early postoperative period, as well as treatment results after 3, 6 and 12 months from the moment of surgery was carried out. RESULTS: The results of treatment of 60 patients in the early postoperative and long-term periods were analyzed. The average operation time was 71.37 ± 8.87 minutes. The average time for clamping the ICA was 18.35 ± 3.9 minutes. Transient ischemic attack in the early postoperative period occurred in 1 (1.7%) patient. Restenosis of the internal carotid artery (≥40%) on the side of the performed reconstruction developed in 3 (5.2%) patients. CONCLUSION: The risk of development of neurological disorders in the early postoperative period, as well as of restenosis of the area of surgical intervention in the long-term period when using the modified technique of eversion carotid endarterectomy, correspond to the data of modern world literature.


2016 ◽  
Vol 4 (12) ◽  
pp. 1215-1216 ◽  
Author(s):  
Yuta Hagiwara ◽  
Tomohide Yoshie ◽  
Takahiro Shimizu ◽  
Hana Ogura ◽  
Masashi Akamatsu ◽  
...  

2021 ◽  
Vol 22 (3) ◽  
pp. 38-47
Author(s):  
A. N. Kazantsev ◽  
K. P. Chernykh ◽  
S. V. Artyukhov ◽  
L. V. Roshkovskaya ◽  
M. O. Janelidze ◽  
...  

Purpose. Analysis of the immediate results of emergency glomus-sparing auto-transplantation of the internal carotid artery (ICA) in the acute period of ischemic stroke, developed on the basis of the City Alexandrovskaya Hospital, St. Petersburg.Material and methods. In this prospective, single-center study from January 2017 to August 2020. 49 patients were included in the acute period of ischemic stroke with hemodynamically significant extended atherosclerotic lesions of the ICA. All patients underwent glomus-sparing ICA autotransplantation, developed on the basis of the City Alexandrovskaya Hospital, St. Petersburg (Kazantsev A. N., Zarkua N. E., Chernykh K. P. et al. Аrteries with extended atherosclerotic lesions of the internal carotid artery. Patent application No. 202.013.4151/14 (062595), filing date 10/16/2020). Glomus-sparing ICA autotransplantation, developed on the basis of the City Alexandrovskaya Hospital, St. Petersburg, was performed as follows. On the inner edge of the external carotid artery (ECA), adjacent to the carotid sinus, 2–3 cm above the orifice, depending on the spread of atherosclerotic plaque (ASB), arteriotomy was performed with the transition to the common carotid artery (CCA) (also 2–3 see below the mouth of the NSA). The ICA was cut off at the site formed by the sections of the wall of the NSA and the CCA. Then the ICA was cut off as distally as possible in front of the hypoglossal nerve, so that the artery was completely resected. In view of the presence of an intact carotid glomus on the resected area of the ICA, which connects it to the wound, endarterectomy from the ICA was performed inside the operating field by its complete eversion. Then, open endarterectomy from ECA and CCA was performed. At the next stage, the ICA was implanted in its previous place with the creation of proximal and distal end-to-end anastomoses, so that the continuing ASB above the endarterectomy zone was fixed with a circular vascular suture.Results. There were no complications in the postoperative period. No cases of restenosis / thrombosis of the reconstruction zone were identified in all the sample according to the color duplex scanning data. On the 7th day after the operation, all patients were diagnosed with regression of neurological symptoms according to the National Institute of Health Stroke Scale: on admission, the mean score was 10.5±3.5; at the moment of the control point — 6.5±1.5; p=0.001. This reflects the effectiveness of the chosen treatment strategy. According to the data on the dynamics of systolic blood pressure, stable systolic parameters were observed in the postoperative period against the background of antihypertensive therapy taken before the operation.Conclusion. Carotid endarterectomy in the acute period of ischemic stroke is safe in the presence of mild neurological deficits (up to 25 points on the National Institute of Health Stroke Scale) and the diameter of the ischemic focus in the brain not exceeding 2.5 cm according to the computer data. tomography. Glomussparing ICA autotransplantation, developed on the basis of the Aleksandrovskaya Hospital, St. Petersburg, does not require the use of a patch and is not characterized by the risk of developing ICA thrombosis as a result of intimal detachment behind the endarterectomy zone. Preservation of the carotid glomus during reconstructive intervention on the ICA prevents the development of labile arterial hypertension and hemorrhagic transformation in the postoperative period.


2020 ◽  
Vol 87 (1-2) ◽  
pp. 11-14
Author(s):  
I. S. Pulyaeva ◽  
V. A. Prasol ◽  
Yu. V. Ivanova

Objective. To analyze the surgical treatment results in patients, suffering carotid arteries stenosis, using endarterectomy in combination with conservative therapy. Materials and methods. Results of treatment were analyzed in 58 patients, suffering hemodynamically significant stenosis of carotid arteries and/or presence of embologenic pluck, in whom from 2017 to 2019 yrs in V. T. Zaytsev Institute of General and Urgent Surgery NAMS of Ukraine, Kharkov intraoperative supportive conservative therapy, taking into account the risk for development of the cerebral ischemia and the reperfusion syndrome, was conducted. There were 52 (89.7%) men and 6 (10.3%) women. Middle age of the patients operated on have constituted (65 ± 15) yrs. Results. Basing on the literature data analyzed as well as on investigation of the thrombocytes aggregation in patients in perioperative period the algorithm of supportive conservative therapy was elaborated: injection of 5000 IU heparin 5 min before the internal carotid artery clamping under the ICT control; injection of Citicoline 1000 mg 5 min before the internal carotid artery clamping to the patients with neurological deficiency in accordance to the neurological test data and with application of a temporary by-pass. In all the patients in postoperative period the complications were absent. Control of the carotid arteries passability and the ischemia zone state on the 14th day was conducted, the carotid arteries stenosis was not revealed. Nonsignificant complications, such as the stressed hematoma, demanding postoperative wound revision and hemostasis performance, were observed in 4 patients. In 2 patients postoperative period was complicated by the hypoglossal nerve paresis because of its squeezing by hematoma. Conclusion. Citicoline injection before the carotid artery clamping in the carotid endarterectomy with a temporary by-pass permits to lower the risk for development of neurological complications, and while development of postoperative reperfusion syndrome –to reduce its signs.


2020 ◽  
Vol 24 (2) ◽  
pp. 109
Author(s):  
A. N. Kazantsev ◽  
R. S. Tarasov ◽  
K. P. Chernykh ◽  
R. Yu. Leader ◽  
N. E. Zarkua ◽  
...  

<p>This article presents the results of treatment of a patient with rupture of a giant intracerebral aneurysm of the left middle cerebral artery (MCA), hemodynamically significant stenosis of the internal carotid artery on the left and the trunk of the left coronary artery with multiple lesions of the coronary arteries (anterior descending artery, diagonal branch, right coronary artery). A phased surgical correction was performed, with the time period between stages being 2 months, as follows:<br />Stage 1 — open microsurgical clipping of the aneurysm of the left MCA and removal of intracerebral hematoma. The usage of the standard treatment volume in the form of 3H therapy (hypertension, haemodilution and hypervolemia), as well as slow calcium channel blockers in the postoperative period, was associated with a high risk of developing cardiovascular complications due to the presence of occlusal–stenotic lesions of the coronary and brachiocephalic channels. In the postoperative period, the patient received antiplatelet therapy (acetylsalicylic acid 100 mg at lunch), lipid-lowering therapy (rosuvastatin 20 mg in the evening) and anti-hypertensive therapy (bisoprolol 2.5 mg in the morning; perindopril 2.5 mg in the evening; spironolactone 25 mg in the morning; torasemide 10 mg in the morning; valparin XP 500 mg 2 times a day). On day 14, the patient was transferred from the intensive care unit, and on day 20, the patient was discharged from the hospital in satisfactory condition.<br />Stage 2 — a combined operation in the amount of carotid endarterectomy (CEE) with plastic surgery of the biological patch on the left with plastic reconstruction of the reconstruction zone with a patch from the xenopericardium and coronary bypass grafting (CABG). Tactics were confirmed as optimal, taking into account the stratification of the risk of complications in the postoperative period when applying the new interactive program ‘Program support for the decision-making process for choosing a surgical re-vascularisation strategy for multifocal atherosclerosis’ (certificate of registration of a computer program RU 2017619457). Brain protection during CEE was achieved by invasive measurement of retrograde pressure (60 % of systemic blood pressure (BP)) and intraoperative increase in blood pressure to 180/90 mm Hg. CABG was performed using cardiopulmonary bypass. An epiaortic ultrasound scan was used to select the position of the implantation of a venous shunt into the aortic wall. Intraoperative flowmetry was used to regulate the quality of the implanted shunts.<br />The patient was discharged 10 days after the surgery from the hospital in satisfactory condition. Conservative therapy, initiated after stage 1 of re-vascularisation, was continued.<br />Clipping of intracerebral arterial aneurysm during its rupture and reconstructive interventions on the internal carotid artery and coronary arteries could be performed combined with the possibility of endovascular correction. However, due to the presence of an unstable atherosclerotic plaque, the possibility of interventional correction of the internal carotid artery was excluded, and the condition of the coronary bed at the time of stage 1 remained unknown. An additional argument in favour of open microsurgical clipping of the aneurysm was the need for the removal of intracerebral hematoma.<br />The treatment strategy chosen here was found to be safe and effective. Satisfactory outcome of the surgery was achieved due to a complete range of perioperative examinations. The implemented tactics prevented the development of complications. The data obtained here would form the basis for the development of recommendations for selecting the optimal tactics of re-vascularisation in combined lesions of intracranial, extracranial and coronary arteries.</p><p>Received 21 April 2020. Revised 27 April 2020. Accepted 28 April 2020.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> Authors declare no conflict of interest.</p><p><strong>Author contributions</strong><br />Conception and design: А.N. Kazantsev, R.S. Tarasov<br />Literature review: K.P. Chernykh, N.E. Zarkua, R.Y. Leader, G.Sh. Bagdavadze<br />Drafting the article: А.N. Kazantsev<br />Illustrations: А.N. Kazantsev, K.P. Chernykh, N.E. Zarkua, R.Y. Leader, G.Sh. Bagdavadze<br />Critical revision of the article: N.E. Zarkua, R.S. Tarasov, Y.P. Linets<br />Final approval of the version to be published: А.N. Kazantsev, R.S. Tarasov, K.P. Chernykh, N.E. Zarkua, R.Y. Leader, <br />G.Sh. Bagdavadze, Y.P. Linets</p>


1992 ◽  
Vol 76 (3) ◽  
pp. 520-523 ◽  
Author(s):  
Robert C. Rostomily ◽  
Marc R. Mayberg ◽  
Joseph M. Eskridge ◽  
Robert Goodkin ◽  
H. Richard Winn

✓ Percutaneous transluminal angioplasty is commonly used for treatment of peripheral vascular disease, but only recently has it been applied to craniocervical lesions. The successful use of percutaneous transluminal angioplasty for treatment of an isolated high-grade stenosis of the petrous internal carotid artery is described in a patient with progressive ischemic symptoms despite maximum medical management. At his 2-year follow-up examination, the patient remained asymptomatic with angiographic evidence of progressive resolution of the stenotic lesion and indirect evidence of improved hemispheric blood flow ipsilateral to the lesion. Percutaneous transluminal angioplasty may provide an effective means of treatment for selective intracranial atherosclerotic stenosis.


Author(s):  
W. Yu. Ussov ◽  
A. S. Maksimova ◽  
V. E. Sinitsyn ◽  
S. I. Karas ◽  
E. E. Bobrikova ◽  
...  

Aim. To study the clinical significance of the gradient of narrowing of arterial lumen (GNL) for atherosclerotic stenosis of the internal carotid artery (ICA) as a risk factor for ischemic brain damage.Material and methods. We proposed a new parameter of hemodynamic severity of ICA atherosclerotic stenosis — GNL. It calculated as ratio of the difference in the ICA cross section areas on the stenotic lesion and the near non-stenotic region to the distance between them: Snorm — Sstenosis)/Dnorm — stenosis, mm2 /mm. We examined 25 patients with advanced atherosclerosis and with uni(n=22) or bilateral (n=3) ICA stenosis >50% according to European Carotid Surgery Trial, and 11 individuals without ICA stenosis. Each participant underwent magnetic resonance angiography (MRA) of the carotid arteries with reconstruction of the arteries from C6-C7 level to the parietal bones, and the GNL was calculated. The thickness of the baseline slice was 0,8-1 mm. Each subject also underwent cerebral magnetic resonance imaging (MRI) in T1-, T2-, PD-, flair-weighted protocols. Results. Patients were divided into groups: group 1 (n=12) — without ischemic injury in the ICA system, and group 2 (n=13)  — with MRI signs ischemic injury history. The groups did not differ in proportion of stenosis (74,9±4,25% and 77,8±3,8%, p<0,05), ICA lumen area on the stenotic lesion (1,05±0,18 mm2 and 1,14±0,17 mm2 , p<0,05) and the ICA diameter at the non-stenotic region (4,30±0,32 mm and 4,9±0,29 mm, p<0,05). In control group, GNL was <0,75 mm2 /mm. Groups 1 and 2 significantly differed (2,47±0,41 mm2 /mm and 4,60±0,51 mm2 /mm, p<0,02). In group 2, 12 out of 13 patients had GNL >3,35 mm2 /mm, and, in group 1, 9 out of 12 — less than 3,35 mm2 /mm. GNL did not correlate significantly with other parameters of ICA stenosis. Two patients with the highest GNL in each group (5,5 and 8,6 mm2 /mm) had a fatal ischemic stroke within six monthsConclusion. Firstly, proposed parameter of stenosis hemodynamic severity GNL is independent, informative and prognostically important indicator for carotid artery atherosclerotic lesion.


VASA ◽  
2011 ◽  
Vol 40 (6) ◽  
pp. 491-494 ◽  
Author(s):  
Vávrová ◽  
Slezácek ◽  
Vávra ◽  
Karlová ◽  
Procházka

Internal carotid artery pseudoaneurysm is a rare complication of deep neck infections. The authors report the case of a 17-year-old male who presented to the Department of Otorhinolaryngology with an acute tonsillitis requiring tonsillectomy. Four weeks after the surgery the patient was readmitted because of progressive swallowing, trismus, and worsening headache. Computed tomography revealed a pseudoaneurysm of the left internal carotid artery in the extracranial segment. A bare Wallstent was implanted primarily and a complete occlusion of the pseudoaneurysm was achieved. The endovascular approach is a quick and safe method for the treatment of a pseudoaneurysm of the internal carotid artery.


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