scholarly journals A non-toxic approach for treatment of breast cancer and its metastases: capecitabine enhanced photodynamic therapy in a murine breast tumor model

2019 ◽  
Vol 2019 ◽  
Author(s):  
Sanjay Anand ◽  
Anton Yasinchak ◽  
Taylor Bullock ◽  
Mukul Govande ◽  
Edward V. Maytin
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Breast Tumor ◽  
Tumor Model ◽  
Toxic Approach ◽  
Breast Tumor Model

Garcinol sensitizes breast cancer cells to Taxol through the suppression of caspase-3/iPLA2and NF-κB/Twist1 signaling pathways in a mouse 4T1 breast tumor model

2017 ◽  
Vol 8 (3) ◽  
pp. 1067-1079 ◽  
Author(s):  
Shih-Hsin Tu ◽  
Yi-Shiou Chiou ◽  
Nagabhushanam Kalyanam ◽  
Chi-Tang Ho ◽  
Li-Ching Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Signaling Pathways ◽  
Breast Tumor ◽  
Breast Cancer Cells ◽  
Caspase 3 ◽  
Tumor Model ◽  
Breast Tumor Model

Garcinol sensitizes breast cancer cells to Taxolviasynergistically inducing antimitotic effects and effectively repressing the activation of caspase-3/iPLA2and Taxol-promoted NF-κB/Twist1 signaling pathways.

Prevention of metastases with a Mage-b DNA vaccine in a mouse breast tumor model: potential for breast cancer therapy

2005 ◽  
Vol 91 (1) ◽  
pp. 19-28 ◽  
Author(s):  
Roza K. Sypniewska ◽  
Lieve Hoflack ◽  
Melissa Tarango ◽  
Susan Gauntt ◽  
Belinda Z. Leal ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Dna Vaccine ◽  
Breast Tumor ◽  
Tumor Model ◽  
Model Potential ◽  
Breast Cancer Therapy ◽  
Breast Tumor Model

scholarly journals A Polysaccharide From the Whole Plant of Plantago asiatica L. Enhances the Antitumor Activity of Dendritic Cell-Based Immunotherapy Against Breast Cancer

2021 ◽  
Vol 12 ◽  
Author(s):  
Jiafeng Gao ◽  
Yi-Nan Zhang ◽  
Jingwen Cui ◽  
Jiatong Zhang ◽  
Yuexiang Ming ◽  
...  
Keyword(s):  
Breast Cancer ◽  
T Cells ◽  
Breast Tumor ◽  
Cytotoxic T Cells ◽  
Tumor Model ◽  
Whole Plant ◽  
Plantago Asiatica ◽  
Breast Tumor Model

Dendritic cells (DCs) are the most potent professional antigen-presenting cells (APCs) that mediate T-cell immune responses. Breast cancer is one of the most commonly diagnosed diseases and its mortality rate is higher than any other cancer in both humans and canines. Plantain polysaccharide (PLP), extracted from the whole plant of Plantago asiatica L., could promote the maturation of DCs. In this research, we found that PLP could upregulate the maturation of DCs both in vitro and in vivo. PLP-activated DCs could stimulate lymphocytes’ proliferation and differentiate naive T cells into cytotoxic T cells. Tumor antigen-specific lymphocyte responses were enhanced by PLP and CIPp canine breast tumor cells lysate-pulsed DCs, and PLP and CIPp-cell-lysate jointly stimulated DCs cocultured with lymphocytes having the great cytotoxicity on CIPp cells. In the 4T1 murine breast tumor model, PLP could control the size of breast tumors and improve immunity by recruiting DCs, macrophages, and CD4+ and CD8+ T cells in the tumor microenvironment. These results indicated that PLP could achieve immunotherapeutic effects and improve immunity in the breast tumor model.

Synergistic effect of glycated chitosan and photofrin photodynamic therapy on different breast tumor model

2020 ◽  
Vol 31 ◽  
pp. 101842
Author(s):  
Xiaojun Cai ◽  
Jieni Feng ◽  
Feng Chen ◽  
Chaofan Guo ◽  
Lingling Sun ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Synergistic Effect ◽  
Breast Tumor ◽  
Tumor Model ◽  
Breast Tumor Model

Mass Spectrometry Imaging of the Hypoxia Marker Pimonidazole in a Breast Tumor Model

2016 ◽  
Vol 88 (6) ◽  
pp. 3107-3114 ◽  
Author(s):  
Nadine E. Mascini ◽  
Menglin Cheng ◽  
Lu Jiang ◽  
Asif Rizwan ◽  
Helen Podmore ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Breast Tumor ◽  
Mass Spectrometry Imaging ◽  
Tumor Model ◽  
Hypoxia Marker ◽  
Breast Tumor Model

Comparison of [18F]Fluorocholine and [18F]Fluordesoxyglucose for assessment of progression, lung metastasis detection and therapy response in murine 4T1 breast tumor model

2018 ◽  
Vol 140 ◽  
pp. 278-288 ◽  
Author(s):  
Brígida Gomes de Almeida Schirmer ◽  
Marina Rios de Araujo ◽  
Marina Bicalho Silveira ◽  
Jousie Michel Pereira ◽  
Lorena Carla Vieira ◽  
...  
Keyword(s):  
Lung Metastasis ◽  
Breast Tumor ◽  
Therapy Response ◽  
Tumor Model ◽  
Breast Tumor Model

Distribution of gadomelitol in a human breast tumor model in mice

2005 ◽  
Vol 18 (3) ◽  
pp. 138-143 ◽  
Author(s):  
C. Corot ◽  
P. Robert ◽  
E. Lancelot ◽  
A. Martinell ◽  
R. Santus
Keyword(s):  
Breast Tumor ◽  
Tumor Model ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Breast Tumor Model
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