scholarly journals Clinical Performance of CAD/CAM All-ceramic Tooth-supported Fixed Dental Prostheses: A Systematic Review and Meta-analysis

2021 ◽  
Author(s):  
Babak Saravi ◽  
Andreas Vollmer ◽  
Maja Hartmann ◽  
Gernot Lang ◽  
Ralf-Joachim Kohal ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prospective Studies ◽  
Clinical Performance ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Success Rates ◽  
Dental Prostheses ◽  
Cad Cam ◽  
Fixed Dental Prostheses

Although CAD/CAM ceramics present a promising alternative to metal-ceramic fixed dental prostheses, little is known about their mid- and long-term clinical performance. This systematic review aims to estimate the survival and success rates and describes the underlying complication characteristics for CAD/CAM tooth-supported fixed dental prostheses (FDPs). We systematically searched MEDLINE and Web of Science to find relevant prospective studies with a follow-up of at least one year. We estimated pooled 1-, 5- and 10-year survival and success rates by combining the collected data in a Poisson regression model. Descriptive statistics were conducted to evaluate the distribution of failures and complications in the included studies. Risk of bias for the included studies was assessed with an adapted checklist for single-arm trials. Pooled estimated 1-, 5-, and 10-year survival rates ranged from 93.80% to 94.66%, 89.67% to 91.1%, and 79.33% to 82.20%, respectively. The corresponding success rates, excluding failures but including any other types of intervention, were 94.53% to 96.77%, 90.89% to 94.62%, and 81.78% to 89.25%. Secondary caries was the most frequent cause of failure, followed by chipping of the veneering. The most common cause of complication, excluding failures but requiring intervention, was chipping of the veneering. Risk of bias was generally acceptable for the included studies, with 7 studies associated with low risk of bias, 8 studies with a moderate risk of bias, and 3 studies with serious risk of bias. The current meta-analysis on CAD/CAM supported FDPs revealed satisfying survival and success rates for up to 10 years of exposure. More prospective studies focusing on long-term performance are needed to strengthen the evidence currently available in the literature.

scholarly journals Clinical Performance of CAD/CAM All-Ceramic Tooth-Supported Fixed Dental Prostheses: A Systematic Review and Meta-Analysis

Materials ◽  
2021 ◽  
Vol 14 (10) ◽  
pp. 2672
Author(s):  
Babak Saravi ◽  
Andreas Vollmer ◽  
Maja Hartmann ◽  
Gernot Lang ◽  
Ralf-Joachim Kohal ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prospective Studies ◽  
Clinical Performance ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Success Rates ◽  
Dental Prostheses ◽  
Cad Cam ◽  
Fixed Dental Prostheses

Although CAD/CAM ceramics present a promising alternative to metal-ceramic fixed dental prostheses, little is known about their mid- and long-term clinical performance. This systematic review aims to estimate the survival and success rates and describes the underlying complication characteristics for CAD/CAM tooth-supported zirconia- and lithium disilicate-based fixed dental prostheses (FDPs). We systematically searched MEDLINE and Web of Science to find relevant prospective studies with a follow-up of at least one year. We estimated pooled 1-, 5-, and 10-year survival and success rates by combining the collected data in a Poisson regression model. Descriptive statistics were conducted to evaluate the distribution of failures and complications in the included studies. Risk of bias for the included studies was assessed with an adapted checklist for single-arm trials. Pooled estimated 1-, 5-, and 10-year survival rates ranged from 93.80% to 94.66%, 89.67% to 91.1%, and 79.33% to 82.20%, respectively. The corresponding success rates excluding failures, but including any other types of intervention were 94.53% to 96.77%, 90.89% to 94.62%, and 81.78% to 89.25%. Secondary caries was the most frequent cause of failure, followed by chipping of the veneering. The most common cause of complication excluding failures but requiring intervention was chipping of the veneering. Risk of bias was generally acceptable for the included studies, with seven studies associated with low risk of bias, eight studies with a moderate risk of bias, and three studies with serious risk of bias. The current meta-analysis on CAD/CAM-supported FDPs revealed satisfying survival and success rates for up to 10 years of exposure. More prospective studies focusing on long-term performance are needed to strengthen the evidence currently available in the literature.

Clinical performance of anterior resin-bonded fixed dental prostheses with different framework designs: A systematic review and meta-analysis

2016 ◽  
Vol 47 ◽  
pp. 1-7 ◽  
Author(s):  
Ya-Ru Wei ◽  
Xiao-Dong Wang ◽  
Qin Zhang ◽  
Xiang-Xia Li ◽  
Markus B. Blatz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Performance ◽  
Meta Analysis ◽  
Dental Prostheses ◽  
Fixed Dental Prostheses

Exercise interventions in lateral elbow tendinopathy have better outcomes than passive interventions, but the effects are small: a systematic review and meta-analysis of 2123 subjects in 30 trials

2020 ◽  
pp. bjsports-2020-102525
Author(s):  
Stefanos Karanasios ◽  
Vasileios Korakakis ◽  
Rod Whiteley ◽  
Ioannis Vasilogeorgis ◽  
Sarah Woodbridge ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Short Term ◽  
Lateral Elbow ◽  
Long Term Follow Up ◽  
Wait And See ◽  
Lateral Elbow Tendinopathy

ObjectiveTo evaluate the effectiveness of exercise compared with other conservative interventions in the management of lateral elbow tendinopathy (LET) on pain and function.DesignSystematic review and meta-analysis.MethodsWe used the Cochrane risk-of-bias tool 2 for randomised controlled trials (RCTs) to assess risk of bias and the Grading of Recommendations Assessment, Development and Evaluation methodology to grade the certainty of evidence. Self-perceived improvement, pain intensity, pain-free grip strength (PFGS) and elbow disability were used as primary outcome measures.Eligibility criteriaRCTs assessing the effectiveness of exercise alone or as an additive intervention compared with passive interventions, wait-and-see or injections in patients with LET.Results30 RCTs (2123 participants, 5 comparator interventions) were identified. Exercise outperformed (low certainty) corticosteroid injections in all outcomes at all time points except short-term pain reduction. Clinically significant differences were found in PFGS at short-term (mean difference (MD): 12.15, (95% CI) 1.69 to 22.6), mid-term (MD: 22.45, 95% CI 3.63 to 41.3) and long-term follow-up (MD: 18, 95% CI 11.17 to 24.84). Statistically significant differences (very low certainty) for exercise compared with wait-and-see were found only in self-perceived improvement at short-term, pain reduction and elbow disability at short-term and long-term follow-up. Substantial heterogeneity in descriptions of equipment, load, duration and frequency of exercise programmes were evident.ConclusionsLow and very low certainty evidence suggests exercise is effective compared with passive interventions with or without invasive treatment in LET, but the effect is small.PROSPERO registration numberCRD42018082703.

Survival and complications of monolithic ceramic for tooth-supported fixed dental prostheses: A systematic review and meta-analysis

2021 ◽  
Author(s):  
Letícia Cerri Mazza ◽  
Cleidiel Aparecido Araujo Lemos ◽  
Aldiéris Alves Pesqueira ◽  
Eduardo Piza Pellizzer
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Dental Prostheses ◽  
Fixed Dental Prostheses

scholarly journals Long-term Short Implants Performance: Systematic Review and Meta-Analysis of the Essential Assessment Parameters

2015 ◽  
Vol 26 (4) ◽  
pp. 325-336 ◽  
Author(s):  
Thais Marques Simek Vega Gonçalves ◽  
Sergio Bortolini ◽  
Matteo Martinolli ◽  
Bruna Fernandes Moreira Alfenas ◽  
Daiane Cristina Peruzzo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Survival Rate ◽  
Clinical Performance ◽  
Meta Analysis ◽  
Implant Failure ◽  
Cochrane Library ◽  
Implant Survival ◽  
Implant Survival Rate ◽  
Short Implants

<p>Lack of standard criteria in the outcome assessment makes it difficult to draw conclusions on the clinical performance of short implants and, under these circumstances, determine the reasons for implant failure. This study evaluated, through a systematic review of the literature and meta-analysis, the essential parameters required to assess the long-term clinical performance of short and extra-short implants. Electronic databases (Pubmed-MEDLINE, Cochrane Library Database, Embase, and Lilacs) were searched by two independent reviewers, without language limitation, to identify eligible papers. References from the selected articles were also reviewed. The review included clinical trials involving short dental implants placed in humans, published between January 2000 and March 2014, which described the parameters applied for outcome's measurements and provided data on survival rates. Thirteen methodologically acceptable studies were selected and 24 parameters were identified. The most frequent parameters assessed were the marginal bone loss and the cumulative implant survival rate, followed by implant failure rate and biological complications such as bleeding on probing and probing pocket depths. Only cumulative implant survival rate data allows meta-analysis revealing a positive effect size (from 0.052 (fixed) to 0.042 (random)), which means that short implant appears to be a successful treatment option. Mechanical complications and crown-to-implant (C/I) ratio measurement were also commonly described, however, considering the available evidence; no strong conclusions could be drawn since different methods were used to assess each parameter. By means of this literature review, a standard evaluation scheme is proposed, being helpful to regiment further investigations and comparisons on future studies.</p>

scholarly journals Clinical performance of monolithic CAD/CAM tooth-supported zirconia restorations: systematic review and meta-analysis

2021 ◽  
Author(s):  
Celina Inês Miranda Brito Leitão ◽  
Gustavo Vicentis de Oliveira Fernandes ◽  
Luís Pedro Pereira Azevedo ◽  
Filipe Miguel Araújo ◽  
Helena Donato ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Performance ◽  
Meta Analysis ◽  
Cad Cam

scholarly journals Proton pump inhibitors do not increase the risk of dementia: a systematic review and meta-analysis of prospective studies

2020 ◽  
Vol 33 (10) ◽  
Author(s):  
Madhav Desai ◽  
Venkat Nutalapati ◽  
Sachin Srinivasan ◽  
Jihan Fathallah ◽  
Chandra Dasari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Proton Pump ◽  
Prospective Studies ◽  
Case Reports ◽  
Meta Analysis ◽  
Case Series ◽  
Extensive Literature ◽  
Meta Regression

SUMMARY Published studies have reported variable results on the association between duration of proton pump inhibitor (PPI) use and the risk of dementia. An extensive literature search was performed in PubMed, Embase, Google Scholar, and Cochrane for studies examining the risk of cognitive decline and dementia among PPI users versus non-PPI users in prospective studies. Retrospective database linkage studies, case reports, case series, editorials, uncontrolled cohort studies, cross-sectional studies, and review articles were excluded. Primary outcome was pooled hazard rate (HR) of any dementia among PPI users compared with non-PPI users. Secondary outcomes were pooled HR of Alzheimer’s dementia (AD) and risk with long-term PPI follow-up (more than 5 years) studies. Meta-analysis outcomes, heterogeneity (I2), and meta-regression (for the effect of covariates) were derived by statistical software R and Open meta-analyst. A total of six studies (one RCT and five prospective) with 308249 subjects, average age of 75.8 ± 5.2 years, and follow-up of 5 (range 1.5–11) years were included in the analysis. Pooled HR of any dementia was 1.16 (n = 6, 95% confidence interval (CI) = 0.86–1.47). Results remained unchanged when only studies with long-term PPI use (more than 5 years) were analyzed (n = 4, pooled HR 1.10, 95% CI 0.66–1.53). Finally, the pooled HR for AD was 1.06 (n = 3, 95% CI 0.70–1.41). There was substantial heterogeneity among inclusion studies (I2 = 93%). Meta-regression did not demonstrate a significant role of age at study start (P = 0.1) or duration of PPI use (P = 0.62) to incident dementia. The results of this systematic review and meta-analysis do not show a significant relationship between PPI use and dementia in prospective studies with at least a 5-year follow-up.

A systematic review and meta-analysis of 3-unit fixed dental prostheses: Are the results of 2 abutment implants comparable to the results of 2 abutment teeth?

2017 ◽  
Vol 45 (2) ◽  
pp. 147-160 ◽  
Author(s):  
C. W. P. Pol ◽  
G. M. Raghoebar ◽  
W. Kerdijk ◽  
G. C. Boven ◽  
M. S. Cune ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Dental Prostheses ◽  
Abutment Teeth ◽  
Fixed Dental Prostheses
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