scholarly journals Bone-marrow-aspirate-concentrate for chondral defects: surgical techniques, clinical applications and basic science

2018 ◽  
Vol 3 ◽  
pp. 107-107 ◽  
Author(s):  
Markus Neubauer ◽  
Vivek Jeyakumar ◽  
Thomas Muellner ◽  
Stefan Nehrer
SICOT-J ◽  
2017 ◽  
Vol 3 ◽  
pp. 17 ◽  
Author(s):  
Mohamed A. Imam ◽  
Samer S.S. Mahmoud ◽  
James Holton ◽  
Dalia Abouelmaati ◽  
Yasser Elsherbini ◽  
...  

2016 ◽  
Vol 8 (3) ◽  
Author(s):  
James Holton ◽  
Mohamed Imam ◽  
Jonathan Ward ◽  
Martyn Snow

There has been great interest in bone marrow aspirate concentrate (BMAC) as a cost effective method in delivering mesenchymal stem cells (MSCs) to aid in the repair and regeneration of cartilage defects. Alongside MSCs, BMAC contains a range of growth factors and cytokines to support cell growth following injury. However, there is paucity of information relating to the basic science underlying BMAC and its exact biological role in supporting the growth and regeneration of chondrocytes. The focus of this review is the basic science underlying BMAC in relation to chondral damage and regeneration.


SICOT-J ◽  
2017 ◽  
Vol 3 ◽  
pp. 58 ◽  
Author(s):  
Mohamed A. Imam ◽  
James Holton ◽  
Saman Horriat ◽  
Ahmed S. Negida ◽  
Florian Grubhofer ◽  
...  

2017 ◽  
Vol 41 (11) ◽  
pp. 2213-2220 ◽  
Author(s):  
Mohamed A. Imam ◽  
James Holton ◽  
Lukas Ernstbrunner ◽  
Wojciech Pepke ◽  
Florian Grubhofer ◽  
...  

2021 ◽  
pp. 2140004
Author(s):  
Kathryn A. Farina ◽  
Blake A. Kandah ◽  
Nan M. Sowers ◽  
Gregory A. Moore

Achilles tendon disorders, including tendinopathy and ruptures, are common among competitive runners. Relatively high complication rates, recurring injuries, and the need to return to sport have led to the use of regenerative medical treatment in tendon disorders in competitive athletes. Biologic therapies, including bone marrow aspirate concentrate (BMAC) injections, have been effective in restoring injured tissue in a limited number of cases. In this case, a collegiate cross country runner with Achilles tendon pain underwent years of failed, non-surgical conservative management. The patient’s MRI demonstrated moderate distal calcaneus tendinosis with high-grade partial thickness tearing of the anterior fibers of the Achilles tendon (50% tear). The patient underwent peritendinous injection of BMAC. Post-procedure MRI demonstrated minimal tendinosis of the distal and lateral margins of the Achilles tendon, and no evidence of Achilles tendon tear. The patient followed a progressive return to running program, ultimately training 40 miles per week with minimal Achilles tendon pain.


Sign in / Sign up

Export Citation Format

Share Document