scholarly journals Vagus nerve and phrenic nerve guided systematic nodal dissection for lung cancer

2019 ◽  
Vol 11 (9) ◽  
pp. 4021-4027 ◽  
Author(s):  
Zhenguo Liu ◽  
Yao Liu ◽  
Chunying Xie ◽  
Jiali Yang ◽  
Bo Zeng ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Vagus Nerve ◽  
Phrenic Nerve ◽  
Nodal Dissection ◽  
Systematic Nodal Dissection

scholarly journals Pattern of recurrence of pN2 non-small-cell lung cancer: should postoperative radiotherapy be reconsidered?

2020 ◽  
Vol 59 (1) ◽  
pp. 109-115 ◽  
Author(s):  
Kazuo Nakagawa ◽  
Yukihiro Yoshida ◽  
Masaya Yotsukura ◽  
Shun-ichi Watanabe
Keyword(s):  
Lung Cancer ◽  
Adjuvant Chemotherapy ◽  
Small Cell Lung Cancer ◽  
Postoperative Radiotherapy ◽  
Distant Recurrence ◽  
Small Cell ◽  
Small Cell Lung ◽  
Nodal Dissection ◽  
Systematic Nodal Dissection ◽  
Pattern Of Recurrence

Abstract OBJECTIVES The prognosis of patients with mediastinal lymph node (LN) metastasis (pN2 stage III disease) is still unsatisfactory. Both systemic and local recurrence should be prevented after curative surgery. The aim of this study was to explore the pattern of recurrence in patients with completely resected pN2 non-small-cell lung cancer (NSCLC) in the era of adjuvant chemotherapy. METHODS We investigated 337 patients with completely resected cN0-1 and pN2 NSCLC from 2005 to 2016 at National Cancer Center Hospital, Japan. The patterns of recurrence were compared between patients who were managed by observation alone and those with adjuvant chemotherapy. In patients with regional LN recurrence, the pattern and site of recurrence were also explored. RESULTS There were 195 (58.5%) men and 142 (41.5%) women with a mean age of 63.2 years. Fifty-five (16.3%) patients developed only regional LN recurrence, 116 (32.6%) patients developed only distant recurrence and 65 (19.3%) patients developed both regional LN recurrence and distant recurrence. The difference in the pattern of recurrence between patients with observation alone and those with adjuvant chemotherapy was not statistically significant (P = 0.145). As for the pattern of regional LN recurrence, 68 (20.2%) patients had LN recurrence inside the systematic nodal dissection area. CONCLUSIONS Regional LN recurrence was observed in >30% of patients with completely resected pN2 NSCLC. About 20% of patients had recurrence inside the systematic nodal dissection area. Postoperative radiotherapy might be considered as an additional treatment strategy for these patients.

A randomized trial of systematic nodal dissection in resectable non-small cell lung cancer

Lung Cancer ◽  
2002 ◽  
Vol 36 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Yi-long Wu ◽  
Zhi-fan Huang ◽  
Si-yu Wang ◽  
Xue-ning Yang ◽  
Wei Ou
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Randomized Trial ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Nodal Dissection ◽  
Systematic Nodal Dissection

scholarly journals WS05.03 How to Perform a Proper Systematic Nodal Dissection in Lung Cancer Surgery

2019 ◽  
Vol 14 (10) ◽  
pp. S1113
Author(s):  
K. Masai ◽  
K. Kaseda ◽  
K. Asakura ◽  
T. Hishida ◽  
H. Asamura
Keyword(s):  
Lung Cancer ◽  
Lung Cancer Surgery ◽  
Cancer Surgery ◽  
Nodal Dissection ◽  
Systematic Nodal Dissection

scholarly journals The Evolving Concept of Complete Resection in Lung Cancer Surgery

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2583
Author(s):  
Ramón Rami-Porta
Keyword(s):  
Lung Cancer ◽  
International Association ◽  
Lung Cancer Surgery ◽  
Residual Tumor ◽  
Complete Resection ◽  
Resection Margins ◽  
The Status ◽  
Nodal Dissection ◽  
Definition Of ◽  
Systematic Nodal Dissection

Different definitions of complete resection were formulated to complement the residual tumor (R) descriptor proposed by the American Joint Committee on Cancer in 1977. The definitions went beyond resection margins to include the status of the visceral pleura, the most distant nodes and the nodal capsule and the performance of a complete mediastinal lymphadenectomy. In 2005, the International Association for the Study of Lung Cancer (IASLC) proposed definitions for complete, incomplete and uncertain resections for international implementation. Central to the IASLC definition of complete resection is an adequate nodal evaluation either by systematic nodal dissection or lobe-specific systematic nodal dissection, as well as the integrity of the highest mediastinal node, the nodal capsule and the resection margins. When there is evidence of cancer remaining after treatment, the resection is incomplete, and when all margins are free of tumor, but the conditions for complete resection are not fulfilled, the resection is defined as uncertain. The prognostic relevance of the definitions has been validated by four studies. The definitions can be improved in the future by considering the cells spread through air spaces, the residual tumor cells, DNA or RNA in the blood, and the determination of the adequate margins and lymphadenectomy in sublobar resections.

scholarly journals Standard Surgical Techniques for Lung Cancer: Pneumonectomy With Systematic Nodal Dissection

Haigan ◽  
2005 ◽  
Vol 45 (3) ◽  
pp. 215-220
Author(s):  
Yasuhisa Ohde ◽  
Haruhiko Kondo ◽  
Takehiro Okumura ◽  
Kazuo Nakagawa
Keyword(s):  
Lung Cancer ◽  
Surgical Techniques ◽  
Nodal Dissection ◽  
Systematic Nodal Dissection

scholarly journals Time trends in surgery for lung cancer in France from 2005 to 2012: a nationwide study

2015 ◽  
Vol 46 (4) ◽  
pp. 1131-1139 ◽  
Author(s):  
Marie-Catherine Morgant ◽  
Pierre-Benoit Pagès ◽  
Bastien Orsini ◽  
Pierre-Emmanuel Falcoz ◽  
Pascal-Alexandre Thomas ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Time Trends ◽  
Pulmonary Resection ◽  
Early Stage ◽  
Small Cell ◽  
National Database ◽  
Small Cell Lung ◽  
Nationwide Study ◽  
Nodal Dissection ◽  
Systematic Nodal Dissection

The aim of this study was to assess the evolution of survival in patients treated surgically for non-small cell lung cancer (NSCLC) between 2005 and 2012.From January 2005 to December 2012, 34 006 patients underwent pulmonary resection for NSCLC and were included in the French national database Epithor. Patients' characteristics, procedures and survival were analysed. Survival according to the management was evaluated for each 2-year period separately: 2005–2006, 2007–2008, 2009–2010 and 2011–2012.The proportions of early-stage cancers and adenocarcinomas increased significantly over the periods. 3-year overall survival (OS) increased significantly from 80.5% for the first period to 81.4% for the last period. For the periods 2005–2006 and 2007–2008, 3-year OS was lower after segmentectomy than after lobectomy (77 and 73% versus 82 and 83%, respectively). For the periods 2009–2010 and 2011–2012, 3-year OS in the two sub-groups was similar. OS after bi-lobectomy or pneumonectomy was lower than after lobectomy for all periods analysed. Systematic nodal dissection increased OS for all periods. Chemotherapy but not radiotherapy improved OS in the first 12 postoperative months for all periods.Changes in histological type and stage linked to advances in surgical and medical practices since 2005 led to an increase in OS in patients with surgical-stage NSCLC.

Sign in / Sign up

Export Citation Format

Share Document