scholarly journals Assessing the potential association between Epstein-Barr virus and oral squamous cell carcinoma: a systematic review and meta- analysis

2020 ◽  
Vol 9 (4) ◽  
pp. 3092-3100 ◽  
Author(s):  
Shivaranjhany Sivakumar ◽  
Archana A. Gupta ◽  
Nik Mohd Mazuan Nik Mohd Rosdy ◽  
Annapurny Venkiteswaran ◽  
A. Thirumal Raj ◽  
...  
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Epstein Barr Virus ◽  
Meta Analysis ◽  
Barr Virus ◽  
Potential Association ◽  
Epstein Barr

scholarly journals Etiologic Association between Epstein–Barr Virus and Oral Squamous Cell Carcinoma: A Brief Evidence-based Discussion

2017 ◽  
Vol 18 (4) ◽  
pp. 261-264
Author(s):  
Shankargouda Patil ◽  
Barnali Majumdar
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Epstein Barr Virus ◽  
Evidence Based ◽  
Barr Virus ◽  
Epstein Barr

How to cite this article Majumdar B, Sarode SC, Sarode GS, Patil S. Etiologic Association between Epstein–Barr Virus and Oral Squamous Cell Carcinoma: A Brief Evidence-based Discussion. J Contemp Dent Pract 2017;18(4):261-264.

scholarly journals Prevalence of salivary Epstein-Barr virus in potentially malignant oral disorders and oral squamous cell carcinoma

2016 ◽  
pp. e157-e160 ◽  
Author(s):  
L Bagan ◽  
MD Ocete-Monchon ◽  
M Leopoldo-Rodado ◽  
J Murillo-Cortes ◽  
J Diaz-Fernandez ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Potentially Malignant ◽  
Epstein Barr

Prevalence of Epstein-Barr virus in oral squamous cell carcinoma

1999 ◽  
Vol 189 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Ieyoshi Kobayashi ◽  
Kaori Shima ◽  
Ichiro Saito ◽  
Tamotsu Kiyoshima ◽  
Kou Matsuo ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Epstein–Barr Virus Infection of Oral Squamous Cells

2020 ◽  
Vol 8 (3) ◽  
pp. 419 ◽  
Author(s):  
Chukkris Heawchaiyaphum ◽  
Hisashi Iizasa ◽  
Tipaya Ekalaksananan ◽  
Ati Burassakarn ◽  
Tohru Kiyono ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Epstein Barr Virus ◽  
Squamous Cells ◽  
Barr Virus ◽  
Ebv Infection ◽  
Epstein Barr

The Epstein–Barr virus (EBV) is a human herpesvirus associated with various cancers. The number of reports that describe infection of EBV in oral squamous carcinoma cells is increasing. However, there is no available in vitro model to study the possible role of EBV in the development of oral squamous cell carcinoma. Herein, we report establishment of a latent EBV infection of well-differentiated HSC1 cells and poorly differentiated SCC25 cells. Viral copy numbers per cell in EBV-infected HSC1 and SCC25 cells are 2 and 5, respectively. Although the EBV copy number was small, spontaneous viral replication was observed in EBV-infected HSC1 cells. Contrarily, infectious viral production was not observed in EBV-infected SCC25 cells, despite containing larger number of EBV genomes. Chemical activation of cells induced expression of viral lytic BZLF1 gene in EBV-infected HSC1 cells, but not in EBV-infected SCC25 cells. EBV infection activated proliferation and migration of HSC1 cells. However, EBV-infection activated migration but not proliferation in SCC25 cells. In conclusion, EBV can infect squamous cells and establish latent infection, but promotion of cell proliferation and of lytic EBV replication may vary depending on stages of cell differentiation. Our model can be used to study the role of EBV in the development of EBV-associated oral squamous cell carcinoma.

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