Seroprevalence of Hepatitis B Virus among antenatal clinic attendees in Gamawa Local Government Area, Bauchi State, Nigeria

Abstract Background: Hepatitis B is a potentially life-threatening liver infection and a major global health problem. It causes chronic infection and puts people at high risk of death from cirrhosis and liver cancer. WHO estimated 257 million people are living with hepatitis B virus (HBV) infection and in 2015 alone HBV resulted in to 887,000 deaths globally. We determined the prevalence and associated factors of hepatitis B virus infection among Antenatal Care (ANC) attendees in Gamawa Local Government Area, Bauchi State. Methods: We conducted a descriptive cross-sectional, health facility-based study between March and April 2018. We used systematic random sampling technique to recruit 210 pregnant women aged 15-49 years. With a structured questionnaire, we interviewed the respondents and collected blood sample to test for hepatitis B surface antigen. We calculated frequencies, means, proportions, and tested for associations using Epi Info 7.2 and Microsoft Excel. Results: The mean age of respondents was 24.5 ± 6.0 years; 53.3% of whom were younger than 25 years. All were married, 87.1% had no formal education and up to 90.5% were employed. Overall, 6.7% tested positive for HBsAg; women aged ≥35 years had the highest prevalence (10.5%). None with tertiary education tested positive and women married before 18 years had 6.5% prevalence. Conclusions: The prevalence of HBsAg among pregnant women in Gamawa LGA was 6.7% which is quite lower than the national prevalence reported. We recommended improved surveillance of HBV infection and screening of women attending ANC. Keywords: Hepatitis B virus, Hepatitis B Surface antigen, Prevalence, Pregnancy, Health facilities, Hepatitis B

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Seroprevalence of Hepatitis B Virus among antenatal clinic attendees in Gamawa Local Government Area, Bauchi State, Nigeria

10.21203/rs.2.10126/v3 ◽

2019 ◽

Author(s):

GARBA UMAR MUSTAPHA ◽

Abdulrasul Ibrahim ◽

Muhammad Shakir Balogun ◽

Chukwuma David Umeokonkwo ◽

Aisha Indo Mamman

Keyword(s):

Hepatitis B Virus ◽

Local Government ◽

Hepatitis B ◽

Pregnant Women ◽

Surface Antigen ◽

Hepatitis B Surface Antigen ◽

Local Government Area ◽

Hbv Infection ◽

Risk Of Death ◽

B Virus

Abstract Background: Hepatitis B virus disease is a potentially life-threatening liver infection and a major global health problem. It causes chronic infection and puts people at high risk of death from cirrhosis and liver cancer. WHO estimated 257 million people are living with hepatitis B virus (HBV) infection and in 2015 alone HBV resulted in to 887,000 deaths globally. We determined the prevalence and associated factors of hepatitis B virus infection among Antenatal Care (ANC) attendees in Gamawa Local Government Area, Bauchi State. Methods: We conducted a descriptive cross-sectional, health facility-based study between March and April 2018. We used systematic random sampling technique to recruit 210 pregnant women aged 15-49 years. With a structured questionnaire, we interviewed the respondents and collected blood sample to test for hepatitis B surface antigen. We calculated frequencies, means, proportions, and tested for associations using Epi Info 7.2 and Microsoft Excel. Results: The mean age of respondents was 24.5 ± 6.0 years; 112 (53%) of whom were younger than 25 years. All were married, 183 (87%) had no formal education and up to 190 (90%) were employed. Overall, 14 (6.7%) tested positive for HBsAg; women aged ≥35 years had the highest prevalence (10%). None with tertiary education tested positive and women married before 18 years had 13 (6.2%) prevalence. Conclusions: The prevalence of HBsAg among pregnant women in Gamawa LGA was 6.7% which is quite lower than the national prevalence reported. We recommended improved surveillance of HBV infection and screening of women attending ANC. Keywords: Hepatitis B virus, Hepatitis B Surface antigen, Prevalence, Pregnancy, Health facilities, Hepatitis B

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Seroprevalence of Hepatitis B Virus among antenatal clinic attendees in Gamawa Local Government Area, Bauchi State, Nigeria

10.21203/rs.2.10126/v2 ◽

2019 ◽

Author(s):

GARBA UMAR MUSTAPHA ◽

Abdulrasul Ibrahim ◽

Muhammad Shakir Balogun ◽

Chukwuma David Umeokonkwo ◽

Aisha Indo Mamman

Keyword(s):

Hepatitis B Virus ◽

Local Government ◽

Hepatitis B ◽

Pregnant Women ◽

Surface Antigen ◽

Hepatitis B Surface Antigen ◽

Local Government Area ◽

Hbv Infection ◽

Risk Of Death ◽

B Virus

Abstract Background: Hepatitis B is a potentially life-threatening liver infection and a major global health problem. It causes chronic infection and puts people at high risk of death from cirrhosis and liver cancer. WHO estimated 257 million people are living with hepatitis B virus (HBV) infection and in 2015 alone HBV resulted in to 887,000 deaths globally. We determined the prevalence and associated factors of hepatitis B virus infection among Antenatal Care (ANC) attendees in Gamawa Local Government Area, Bauchi State. Methods: We conducted a descriptive cross-sectional, health facility-based study between March and April 2018. We used systematic random sampling technique to recruit 210 pregnant women aged 15-49 years. With a structured questionnaire, we interviewed the respondents and collected blood sample to test for hepatitis B surface antigen. We calculated frequencies, means, proportions, and tested for associations using Epi Info 7.2 and Microsoft Excel. Results: The mean age of respondents was 24.5 ± 6.0 years; 112 (53%) of whom were younger than 25 years. All were married, 183 (87%) had no formal education and up to 190 (90%) were employed. Overall, 14 (6.7%) tested positive for HBsAg; women aged ≥35 years had the highest prevalence (10%). None with tertiary education tested positive and women married before 18 years had 13 (6.2%) prevalence. Conclusions: The prevalence of HBsAg among pregnant women in Gamawa LGA was 6.7% which is quite lower than the national prevalence reported. We recommended improved surveillance of HBV infection and screening of women attending ANC. Keywords: Hepatitis B virus, Hepatitis B Surface antigen, Prevalence, Pregnancy, Health facilities, Hepatitis B

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Seroprevalence of Hepatitis B Virus among antenatal clinic attendees in Gamawa Local Government Area, Bauchi State, Nigeria

10.21203/rs.2.10126/v6 ◽

2020 ◽

Author(s):

GARBA UMAR MUSTAPHA ◽

Abdulrasul Ibrahim ◽

Muhammad Shakir Balogun ◽

Chukwuma David Umeokonkwo ◽

Aisha Indo Mamman

Keyword(s):

Hepatitis B Virus ◽

Local Government ◽

Hepatitis B ◽

Pregnant Women ◽

Surface Antigen ◽

Hepatitis B Surface Antigen ◽

Local Government Area ◽

Hbv Infection ◽

Risk Of Death ◽

B Virus

Abstract Background: Hepatitis B virus disease is a potentially life-threatening liver infection and a major global health problem. It causes chronic infection and puts people at high risk of death from cirrhosis and liver cancer. WHO estimated 257 million people are living with hepatitis B virus (HBV) infection and in 2015 alone HBV resulted in to 887,000 deaths globally. We determined the prevalence and associated factors of hepatitis B virus infection among Antenatal Care (ANC) attendees in Gamawa Local Government Area, Bauchi State. Methods: We conducted a descriptive cross-sectional, health facility-based study between March and April 2018. We used systematic random sampling technique to recruit 210 pregnant women aged 15-49 years. With a structured questionnaire, we interviewed the respondents and collected blood sample to test for hepatitis B surface antigen. We calculated frequencies, means, proportions, and tested for associations using Epi Info 7.2 and Microsoft Excel. Results: The mean age of respondents was 24.5 ± 6.0 years; 112 (53%) of whom were younger than 25 years. All were married, 183 (87%) had no formal education and up to 190 (90%) were employed. Overall, 14 (6.7%) tested positive for HBsAg; women aged ≥35 years had the highest prevalence (10%). None with tertiary education tested positive and women married before 18 years had 13 (6.2%) prevalence. Conclusions: The prevalence of HBsAg among pregnant women in Gamawa LGA was 6.7% which is quite lower than the national prevalence reported. We recommended improved surveillance of HBV infection and screening of women attending ANC. Keywords: Hepatitis B virus, Hepatitis B Surface antigen, Prevalence, Pregnancy, Health facilities, Hepatitis B

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Seroprevalence of Hepatitis B Virus among antenatal clinic attendees in Gamawa Local Government Area, Bauchi State, Nigeria

10.21203/rs.2.10126/v4 ◽

2020 ◽

Author(s):

GARBA UMAR MUSTAPHA ◽

Abdulrasul Ibrahim ◽

Muhammad Shakir Balogun ◽

Chukwuma David Umeokonkwo ◽

Aisha Indo Mamman

Keyword(s):

Hepatitis B Virus ◽

Local Government ◽

Hepatitis B ◽

Pregnant Women ◽

Surface Antigen ◽

Hepatitis B Surface Antigen ◽

Local Government Area ◽

Hbv Infection ◽

Risk Of Death ◽

B Virus

Abstract Background: Hepatitis B virus disease is a potentially life-threatening liver infection and a major global health problem. It causes chronic infection and puts people at high risk of death from cirrhosis and liver cancer. WHO estimated 257 million people are living with hepatitis B virus (HBV) infection and in 2015 alone HBV resulted in to 887,000 deaths globally. We determined the prevalence and associated factors of hepatitis B virus infection among Antenatal Care (ANC) attendees in Gamawa Local Government Area, Bauchi State. Methods: We conducted a descriptive cross-sectional, health facility-based study between March and April 2018. We used systematic random sampling technique to recruit 210 pregnant women aged 15-49 years. With a structured questionnaire, we interviewed the respondents and collected blood sample to test for hepatitis B surface antigen. We calculated frequencies, means, proportions, and tested for associations using Epi Info 7.2 and Microsoft Excel. Results: The mean age of respondents was 24.5 ± 6.0 years; 112 (53%) of whom were younger than 25 years. All were married, 183 (87%) had no formal education and up to 190 (90%) were employed. Overall, 14 (6.7%) tested positive for HBsAg; women aged ≥35 years had the highest prevalence (10%). None with tertiary education tested positive and women married before 18 years had 13 (6.2%) prevalence. Conclusions: The prevalence of HBsAg among pregnant women in Gamawa LGA was 6.7% which is quite lower than the national prevalence reported. We recommended improved surveillance of HBV infection and screening of women attending ANC. Keywords: Hepatitis B virus, Hepatitis B Surface antigen, Prevalence, Pregnancy, Health facilities, Hepatitis B

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Prevalence of Hepatitis B Virus (HBV) among Antenatal Clinic Attendees in Karu Local Government Area, Nasarawa State, Nigeria

International Journal of Pathogen Research ◽

10.9734/ijpr/2021/v8i430209 ◽

2021 ◽

pp. 1-5

Author(s):

J. C. Ndubuisi ◽

Mohammed Aisha ◽

Chris Akunneh Wariso ◽

D. C. Ejiofor

Keyword(s):

Hepatitis B Virus ◽

Local Government ◽

Hepatitis B ◽

Hepatitis B Surface Antigen ◽

Sampling Technique ◽

Antenatal Clinic ◽

Local Government Area ◽

Hbv Infection ◽

Cross Sectional ◽

B Virus

The aim of this research was to determine the prevalence of Hepatitis B virus (HBsAg) among antenatal clinic attendees in Massaka, Karu Local Government Area of Nassarawa State, North Central Nigeria. Formal consent was obtained from the State Hospital Board to carry out the survey. The study which involved 200 pregnant women aged 18-45 years randomly selected using a systematic random sampling technique was conducted between the months of May-June was a cross sectional health facility-based study. Structured questionnaire was used to generate data from respondents, after which blood samples aseptically collected were screened for hepatitis B surface antigen. Socio-demographic characteristics as well as some of the factors that influence infection were evaluated. Results obtained from the study revealed a 6.5% prevalence rate of infection in the studied population. Prevalence of infection among the subjects within the age range of 35-45 years was lowest (5.8%). However, while it was 5.2% for the married, it was 6.6% for the unmarried. Prevalence of infection was higher among the category with no formal education. Similarly, prevalence was higher among the rural dwellers (6.8%) than their urban counterparts (5.6%). Factors examined were not statistically significant predisposing to HBV infection. In conclusion, the prevalence of HBsAg among ante-natal clinic attendees in Masaka was (6.5%) lower than the reported national prevalence (14.1%). Owing the outcome of this study, it is recommended that improved surveillance for HBV infection and screening of women attending ANC be instituted.

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Discrepant Hepatitis B Surface Antigen Results in Pregnant Women Screened to Identify Hepatitis B Virus Infection

The Journal of Pediatrics ◽

10.1016/j.jpeds.2014.06.043 ◽

2014 ◽

Vol 165 (4) ◽

pp. 773-778 ◽

Cited By ~ 3

Author(s):

Steven L. Veselsky ◽

Tanja Y. Walker ◽

Nancy Fenlon ◽

Chong-Gee Teo ◽

Trudy V. Murphy

Keyword(s):

Hepatitis B Virus ◽

Virus Infection ◽

Hepatitis B ◽

Pregnant Women ◽

Surface Antigen ◽

Hepatitis B Surface Antigen ◽

Hepatitis B Virus Infection ◽

B Virus

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Evaluation of hepatitis B virus transmission and antiviral therapy among hepatitis B surface antigen-positive pregnant women

Journal of Obstetrics and Gynaecology Research ◽

10.1111/jog.12821 ◽

2015 ◽

Vol 41 (12) ◽

pp. 1870-1876 ◽

Cited By ~ 6

Author(s):

Suda Tekin Koruk ◽

Ayse Batirel ◽

Sukran Kose ◽

Sila Cetin Akhan ◽

Bilgehan Aygen ◽

...

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Pregnant Women ◽

Antiviral Therapy ◽

Surface Antigen ◽

Hepatitis B Surface Antigen ◽

Virus Transmission ◽

B Virus

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Seroprevalence of Hepatitis B (HBsAg) Infection among Pregnant Women Attending Specialist Hospital Yola, Adamawa State, Nigeria

Journal of Applied Life Sciences International ◽

10.9734/jalsi/2021/v24i530237 ◽

2021 ◽

pp. 41-47

Author(s):

Godly Chessed ◽

Kefas Hellamada Kwala ◽

Aminu Innocent Asika ◽

Sati Danjuma

Keyword(s):

Hepatitis B Virus ◽

Blood Transfusion ◽

Hepatitis B ◽

Marital Status ◽

Pregnant Women ◽

Surface Antigen ◽

Educational Level ◽

Hepatitis B Surface Antigen ◽

Public Health Problem ◽

B Virus

Infection due to Hepatitis B virus is a serious public health problem worldwide, in spite of productive vaccine. Pregnant women infected with hepatitis B virus can transmit the infection to their fetuses and newborns. The aim of the study was to determine the seroprevalence of Hepatitis B infection among pregnant women attending antenatal care at Specialist Hospital Yola. A total of three hundred and thirteen (313) pregnant women were randomly selected for this study. Hepatitis B status was determined by the presence of Hepatitis B surface antigen (HBsAg). A structured questionnaire was used for the data collection. Sera from volunteers were collected and tested for hepatitis B surface antigen. Seroprevalence was determined based on age group, educational level, occupation, marital status, religion and history of blood transfusion. The seroprevalence of HBsAg among consented antenatal attendees was 17(5.43%). The study found highest seroprevalence of HBsAg among the pregnant women in the age bracket 26-35 years 52.94%, 52.94% in women with primary school education, 41.18% among the unemployed, 94.12% among the married women, 70.59% among Muslim women, and 76.47% among women that had blood transfusion. The study also revealed that there is a significant relationship between HBsAg and (educational level, marital status) of the study participants (P < 0.05). The Seroprevalence of HBsAg among antenatal attendees at Specialist Hospital Yola, Nigeria, is on the high side. Therefore, early screening of pregnant women for hepatitis at antenatal clinic, would contribute greatly to the timely management of the disease and will prevent possible transmission to their neonates.

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