Hepatocellular carcinoma with right atrial tumor thrombus: a meta-analysis

2020 ◽  
Author(s):  
Shi-Min Yuan ◽  
Yi-Xian Guo
Keyword(s):  
Hepatocellular Carcinoma ◽  
Survival Time ◽  
Transarterial Chemoembolization ◽  
Tumor Thrombus ◽  
Surgical Patients ◽  
Right Atrial ◽  
Categorical Variables ◽  
Fisher Exact Test ◽  
Advanced Hepatocellular Carcinoma ◽  
Atrial Tumor

Abstract Background: Hepatocellular carcinoma with right atrial tumor thrombus is uncommon but with a dismal prognosis. Methods: By comprehensive retrieval of the pertinent literature published since 2000, 53 reports were collected with 187 patients recruited into this study. The quantitative data were expressed in mean±standard deviation with range and median values and were compared by independent samples t -test. The categorical variables were compared by Chi-square or Fisher exact test with continuity correction. Results: The survival rate of patients receiving transarterial chemoembolization was 33.3% and that of surgical patients was 41.9%. The survival time of patients with transarterial chemoembolization treatment was longer than that of surgical patients, but lack of a statistical significance. Conclusions: Even though advanced hepatocellular carcinoma with right atrial thrombus is an aggressive malignancy, the the present study showed that patient prognoses were improved and survival time was elongated with the advances of active treatments such as transarterial chemoembolization and surgical treatments. Active treatments are advised to patients with hepatocellular carcinoma with right atrial tumor thrombus in order to improve patients’ survival.

scholarly journals Hepatocellular carcinoma with right atrial tumor thrombus: a systematic review

2020 ◽  
Author(s):  
Shi-Min Yuan ◽  
Yi-Xian Guo
Keyword(s):  
Hepatocellular Carcinoma ◽  
Survival Rate ◽  
Supportive Care ◽  
Survival Time ◽  
Tumor Thrombus ◽  
Case Reports ◽  
Surgical Patients ◽  
Right Atrial ◽  
Atrial Tumor

Abstract Background: Hepatocellular carcinoma with right atrial tumor thrombus is uncommon but with a dismal prognosis. Methods: By comprehensive literature retrieval of 2000–2019, 53 reports were obtained with 187 patients recruited into this study. The extracted data included patient characteristics, tumor characteristics, treatment, follow-up and outcomes. Statistical analyses applied were student t, Fisher exact and I2 tests. Patients were divided into 6 groups according to the treatment of choices: transarterial chemoembolization (TACE), surgery, radiotherapy, chemotherapy, intervention and supportive care. Results: The overall survival rate of this cohort was 40.8%. The survival rate of patients receiving TACE was 33.3% and that of surgical patients was 41.9%. The survival time of patients with TACE treatment was longer than surgical patients, but lack of statistical significance. Patients were under a follow-up of 15.7±16.6 (median 10) months. Patients receiving radiotherapy had under a longest follow-up among all groups. Intra- and/or extrahepatic recurrence of hepatocellular carcinoma was the major morbidity and also often causes of death. The mortality rates of patients with different treatments in a decremental sequence were supportive care >radiotherapy >surgery >TACE >intervention. No difference was noted in mortality between patients reported from case reports and those from non-case reports. Conclusions: Even though advanced hepatocellular carcinoma with right atrial thrombus is an aggressive malignancy, the present study showed that patients’ prognoses were improved and survival time elongated with active treatments such as TACE and surgery. Active treatments were thus advised to patients with hepatocellular carcinoma with right atrial tumor thrombus.

scholarly journals Hepatocellular carcinoma with right atrial tumor thrombus: a systematic review

2020 ◽  
Author(s):  
Shi-Min Yuan ◽  
Yi-Xian Guo
Keyword(s):  
Hepatocellular Carcinoma ◽  
Systematic Review ◽  
Survival Rate ◽  
Tumor Thrombus ◽  
Case Reports ◽  
Surgical Patients ◽  
Right Atrial ◽  
Interventional Treatment ◽  
Atrial Tumor

Abstract Background: Hepatocellular carcinoma with right atrial tumor thrombus is uncommon but with a dismal prognosis. Methods: By comprehensive retrieval of literature published between 2000 and 2019, 53 reports were obtained with 187 patients recruited into this study. The extracted data included patient characteristics, tumor characteristics, treatment, follow-up and outcomes. Statistical analyses applied were student t , Fisher exact and I 2 tests. Patients were devided into 6 groups according to treatment of choices: transarterial chemoembolization (TACE), surgery, radiotherapy, chemotherapy, interventional treatment and supportive care. Results: The overall survival rate of this cohort was 40.8%. The survival rate of patients receiving TACE was 33.3% and that of surgical patients was 41.9%. The survival time of patients with TACE was longer than surgical patients, but lack of a statistical significance. Patients had a follow-up of 15.7±16.6 (median 10) months. The patients receiving radiotherapy had the longest follow-up among all groups. Intra- and/or extrahepatic recurrence of hepatocellular carcinoma was the major mobidity. The mortality rates in a decremental sequence for patients receiving different treatments were supportive care >radiotherapy >surgery >TACE >interventional treatment. No difference was found in mortality between patients reported from case reports and those from non-case reports. Conclusions: Even though advanced hepatocellular carcinoma with right atrial thrombus is an aggressive malignancy, the the present study showed that patients’ prognosis was improved and survival time elongated with active treatments such as TACE and surgery. The present systematic review reveals improved outcomes with active treatments against conservative treatments.

Hepatocellular carcinoma with right atrial tumor thrombus

2020 ◽  
Author(s):  
Yi-Xian Guo
Keyword(s):  
Hepatocellular Carcinoma ◽  
Survival Rate ◽  
Supportive Care ◽  
Tumor Thrombus ◽  
Case Reports ◽  
Surgical Patients ◽  
Right Atrial ◽  
Interventional Treatment ◽  
Atrial Tumor

Abstract Background Hepatocellular carcinoma with right atrial tumor thrombus is uncommon but with a dismal prognosis. Methods By comprehensive retrieval of literature published between 2000 and 2019, 53 reports were obtained with 187 patients recruited into this study. The extracted data included patient characteristics, tumor characteristics, treatment, follow-up and outcomes. Statistical analyses applied were student t, Fisher exact and I2 tests. Patients were devided into 6 groups according to treatment of choices: transarterial chemoembolization (TACE), surgery, radiotherapy, chemotherapy, interventional treatment and supportive care. Results The overall survival rate of this cohort was 40.8 %. The survival rate of patients receiving TACE was 33.3 % and that of surgical patients was 41.9 %. The survival time of patients with TACE was longer than surgical patients, but lack of a statistical significance. Patients had a follow-up of 15.7 ± 16.6 (median 10) months. The patients receiving radiotherapy had the longest follow-up among all groups. Intra- and/or extrahepatic recurrence of hepatocellular carcinoma was the major morbidity. The mortality rates in a decremental sequence for patients receiving different treatments were supportive care > radiotherapy > surgery > TACE > interventional treatment. No difference was found in mortality between patients reported from case reports and those from non-case reports. Conclusions Advanced hepatocellular carcinoma with right atrial thrombus is an aggressive malignancy. Based on the results of median survival time, radiotherapy and TACE seemed to be associated with an improved prognosis and possible better survival.

Hepatocellular carcinoma with right atrial tumor thrombus: Report of a case

Surgery Today ◽  
2011 ◽  
Vol 41 (8) ◽  
pp. 1122-1129 ◽  
Author(s):  
Yoshihiro Inoue ◽  
Michihiro Hayashi ◽  
Takahiro Katsumata ◽  
Yuro Shibayama ◽  
Nobuhiko Tanigawa
Keyword(s):  
Hepatocellular Carcinoma ◽  
Tumor Thrombus ◽  
Right Atrial ◽  
Atrial Tumor

scholarly journals The inferior vena cava hanging maneuver for hepatocellular carcinoma with right atrial tumor thrombus

2020 ◽  
Vol 43 (6) ◽  
pp. 705-706
Author(s):  
Yi-Lin Chang ◽  
Kuo-Hua Lin ◽  
Kwong-Chiu Lee ◽  
Yao-Li Chen
Keyword(s):  
Hepatocellular Carcinoma ◽  
Inferior Vena Cava ◽  
Tumor Thrombus ◽  
Inferior Vena ◽  
Vena Cava ◽  
Right Atrial ◽  
Hanging Maneuver ◽  
Atrial Tumor

Palliative External Beam Radiation Therapy for Hepatocellular Carcinoma With Right Atrial Tumor Thrombus

2020 ◽  
Vol 10 (3) ◽  
pp. e183-e187
Author(s):  
Danielle S. Bitterman ◽  
Samantha K. Edgington ◽  
Aoife Kilcoyne ◽  
Daniel W. Kim ◽  
Christine E. Eyler ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiation Therapy ◽  
Tumor Thrombus ◽  
External Beam Radiation Therapy ◽  
External Beam Radiation ◽  
Right Atrial ◽  
External Beam ◽  
Beam Radiation ◽  
Atrial Tumor

scholarly journals Long-term survival after chemoembolization of metastatic right atrial tumor thrombus as a presenting feature of hepatocellular carcinoma: A case study

2012 ◽  
Vol 3 (5) ◽  
pp. 975-977 ◽  
Author(s):  
JUN-HUI SUN ◽  
YUE-LIN ZHANG ◽  
CHUN-HUI NIE ◽  
LI-MING CHEN ◽  
JIAN-DI HE ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Tumor Thrombus ◽  
Right Atrial ◽  
Term Survival ◽  
Long Term Survival ◽  
Atrial Tumor

Twelve-Year Survival After Resection of Hepatocellular Carcinoma with Right Atrial Tumor Thrombus

2021 ◽  
Author(s):  
Sadiq S. Sikora ◽  
Kishore G. S. Bharathy ◽  
Prasad Krishnan ◽  
Prasad Babu
Keyword(s):  
Hepatocellular Carcinoma ◽  
Tumor Thrombus ◽  
Right Atrial ◽  
Atrial Tumor
Sign in / Sign up

Export Citation Format

Share Document