scholarly journals A Laparoscopic Radical Inguinal Lymphadenectomy Approach Partly Preserving Great Saphenous Vein Branches Can Benefit for Patients with Penile Carcinoma

2021 ◽  
Author(s):  
Yongkang Ma ◽  
Weijian Hao ◽  
Huaqi Yin ◽  
Mingkai Zhu ◽  
Bao Guan ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Lower Extremity ◽  
Saphenous Vein ◽  
Penile Cancer ◽  
Great Saphenous Vein ◽  
Penile Carcinoma ◽  
Control Group ◽  
Lower Extremity Edema ◽  
Node Number ◽  
Inguinal Lymphadenectomy

Abstract Background: Inguinal lymphadenectomy (iLAD) is effective for penile carcinoma treatment, but usually results in many complications. This study aims to clinically evaluate the feasibility and clinical significance of a laparoscopic radical iLAD approach partly preserving great saphenous vein branches for penile carcinoma patients. Methods: A total of 48 patients with penile cancer who underwent laparoscopic radical iLAD with retention of the great saphenous vein in Henan Cancer Hospital from 2012 Jan to 2020 Dec was included in this study. Sixteen penile carcinoma patients who underwent laparoscopic radical iLAD preserving parts of superficial branches of the great saphenous vein were identified as the sparing group, and the matched 32 patients who incised those branches were identified as control group. This new procedure was performed by laparoscopy, preserving parts of superficial branches of the great saphenous vein, superficial lateral and medial femoral veins. Clinicopathological features and perioperative variables were recorded. Postoperative complications, including skin flap necrosis, lymphorrhagia, and lower extremity edema were analyzed retrospectively. Results: We found that the operative time of the sparing group is significantly longer than the control group (p = 0.011). There was no statistical difference in intraoperative blood loss, the lymph node number per side, average time to remove the drainage tube and postoperative hospital stay between the two groups. Compared to the control group, the sparing group showed a significantly decreased incidence of lower extremity edema (p = 0.018). The preservation of parts of superficial branches of the great saphenous vein was mainly decreased the incidence of edema below ankle (p = 0.034). Conclusions: This study demonstrated that the iLAD with preserving parts of superficial branches of the great saphenous vein, with a decreased incidence of postoperative complications, is a safe and feasible approach for penile cancer.

scholarly journals Cytokines Produced by Lymphocytes in the Incompetent Great Saphenous Vein

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Ewa Grudzińska ◽  
Andrzej Lekstan ◽  
Ewelina Szliszka ◽  
Zenon P. Czuba
Keyword(s):  
Saphenous Vein ◽  
Oscillatory Flow ◽  
Great Saphenous Vein ◽  
Interleukin 1 ◽  
Lymphocyte Culture ◽  
Chronic Venous Disease ◽  
Control Group ◽  
Venous Disease ◽  
Culture Supernatants ◽  
Necrosis Factor

The pathogenesis of chronic venous disease (CVD) remains unclear, but lately inflammation is suggested to have an important role in its development. This study is aimed at assessing cytokines released by lymphocytes in patients with great saphenous vein (GSV) incompetence. In 34 patients exhibiting oscillatory flow (reflux) in GSV, blood was derived from the cubital vein and from the incompetent sapheno-femoral junction. In 12 healthy controls, blood was derived from the cubital vein. Lymphocyte culture with and without stimulation by phytohemagglutinin (PHA) was performed. Interleukins (IL) 1β, 2, 4, 10, 12 (p70), and 17A; interleukin 1 receptor α (IL-1ra); tumor necrosis factor-α (TNF-α); interferon-gamma (IFN-γ); and RANTES were assessed in culture supernatants by the Bio-Plex assay. In both stimulated and unstimulated samples, in the examined group, IL-1β and IFN-γ had higher concentrations and RANTES had lower concentrations when compared to those in the control group. In the examined group, IL-4 and IL-17A had higher concentrations without stimulation and TNF-α had higher concentrations with stimulation. The GSV samples had higher IL-2, IL-4, IL-12 (p70), and IFN-γ concentrations without stimulation and lower IL-2 and TNF-α concentrations with stimulation when compared to those of the upper limb in the examined group. These observations indicate that the oscillatory flow present in incompetent veins causes changes in the cytokine production by lymphocytes, promoting a proinflammatory profile. However, the relations between immunological cells, cytokines, and the endothelium require more insight.

Experienced operators achieve superior patency and wound complication rates with endoscopic great saphenous vein harvest compared with open harvest in lower extremity bypasses

2019 ◽  
Vol 70 (5) ◽  
pp. 1534-1542 ◽  
Author(s):  
Matthew Kronick ◽  
Timothy K. Liem ◽  
Enjae Jung ◽  
Cherrie Z. Abraham ◽  
Gregory L. Moneta ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Saphenous Vein ◽  
Great Saphenous Vein ◽  
Wound Complication ◽  
Complication Rates

scholarly journals IP185. Novel Technique for Lower Extremity Reverse Saphenous Vein Bypass—Use of Fistula Formation During Great Saphenous Vein Harvest

2019 ◽  
Vol 69 (6) ◽  
pp. e160-e161
Author(s):  
Michael S. Segal ◽  
Bishoy Emmanuel ◽  
Mohammad Gilani ◽  
Mohan Badhey ◽  
Mahalingham Sivakumar
Keyword(s):  
Lower Extremity ◽  
Saphenous Vein ◽  
Great Saphenous Vein ◽  
Fistula Formation ◽  
Novel Technique ◽  
Saphenous Vein Bypass ◽  
Vein Bypass

The relation among the diameter of the great saphenous vein, clinical state and haemodynamic pattern of the saphenofemoral junction in chronic superficial venous insufficiency

2007 ◽  
Vol 22 (5) ◽  
pp. 207-213 ◽  
Author(s):  
A Mdez-Herrero ◽  
J Gutiérrez ◽  
L Camblor ◽  
J Carreño ◽  
J Llaneza ◽  
...  
Keyword(s):  
Surgical Approach ◽  
Saphenous Vein ◽  
Chronic Venous Insufficiency ◽  
Venous Insufficiency ◽  
Great Saphenous Vein ◽  
Clinical State ◽  
Control Group ◽  
Superficial Venous Insufficiency ◽  
Saphenofemoral Junction

Objective: To find out if there is a relation among the diameter of the great saphenous vein (GSV) when it is incompetent, the clinical gravity of the varicose syndrome and the type of insufficiency of the saphenofemoral junction (SFJ) in patients with chronic venous insufficiency (CVI) by means of duplex exploration. Methods: The sample included 145 extremities, 38 normal as a control group and 107 with incompetence of the GSV. According to the results of the Valsalva and Parana manoeuvres in the SFJ, they were distributed into four groups. The diameter of the GSV and the clinical state according to the clinical, aetiological, anatomical and pathological element classification were recorded for each group. Results: Statistically significant differences were obtained for the diameter and the clinical state in patients with positive manoeuvres with regard to other groups. The diameter was greater and the clinical state more severe (C4, C5 and C6) when two manoeuvres were positive. Conclusions: The presence of both positive manoeuvres in the SFJ is related to severe clinical states and greater diameters of the GSV, allowing the establishment of a prognosis of the CVI and the most suitable surgical approach.

Graduated compression stockings effects on chronic venous disease signs and symptoms during pregnancy

2019 ◽  
Vol 35 (1) ◽  
pp. 46-55 ◽  
Author(s):  
Orlando Adas Saliba Júnior ◽  
Hamilton Almeida Rollo ◽  
Orlando Saliba ◽  
Marcone Lima Sobreira
Keyword(s):  
Pregnant Women ◽  
Saphenous Vein ◽  
Great Saphenous Vein ◽  
Varicose Veins ◽  
Intervention Group ◽  
Signs And Symptoms ◽  
Lower Limbs ◽  
Control Group ◽  
Venous Disease ◽  
Compression Stockings

Objectives To evaluate the effectiveness of compression stockings in controlling the varicose veins in pregnant women. Method A prospective controlled randomized clinical trial was performed, including 60 women: intervention group (n = 30), who used compression stockings, and control group (n = 30). Diameters of the great saphenous vein and small saphenous vein in the lower limbs of pregnant women in an orthostatic position were analyzed using Duplex-ultrasound. The symptomatology and CEAP were evaluated. Results Great saphenous vein diameters in the intervention group were 0.37 cm initial and 0.32 cm final (p < 0.0001) in the right leg and 0.28 cm and 0.38 cm (p < 0.0001) in the control group. CEAP classification presented worsening in the control group (p < 0.0001). The signs and symptoms in the control vs. intervention group: pain (86.67% vs. 23.33%; p < 0.0001), edema (70.00% vs. 33.33%; p = 0.0045), and leg heaviness (93.33% vs. 13.33%; p < 0.0001). Conclusions Compression stockings were effective in controlling the varicose veins related to pregnancy.

Compression stocking prevents increased venous retrograde flow time in the lower limbs of pregnant women

2020 ◽  
Vol 35 (10) ◽  
pp. 784-791
Author(s):  
Orlando Adas Saliba Junior ◽  
Hamilton Almeida Rollo ◽  
Orlando Saliba ◽  
Marcone Lima Sobreira
Keyword(s):  
Pregnant Women ◽  
Saphenous Vein ◽  
Great Saphenous Vein ◽  
Intervention Group ◽  
Lower Limbs ◽  
Control Group ◽  
Venous Reflux ◽  
Compression Stockings ◽  
Reflux Time ◽  
Significant Difference

Objectives To analyze the effect of graduated compression stockings on the venous reflux in the lower limbs of pregnant women. Method A controlled randomized clinical trial was performed with sixty women: intervention group (n = 30), who used compression stockings, and control group (n = 30). Using duplex-ultrasound, the reflux time and peak reflux velocity in the great saphenous vein and small saphenous vein were analyzed. Results Great saphenous vein reflux times in the intervention group were 0.13 s at the beginning (initial) and 0.04 s at the end of pregnancy (final) in the right leg and 0.02 s and 0.34 s (p < 0.0001) in the control group. No patient in the intervention group experienced pathological reflux at the end of the pregnancy. There was a significant difference in the reflux time measured from both the great saphenous vein and small saphenous vein and peak reflux velocity between the groups. Conclusion Compression stockings prevent increased venous reflux in lower limbs of pregnant women.

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