Association of Bleb Formation With Peri-aneurysmal Contact in Unruptured Intracranial Aneurysms

2021 ◽  
Author(s):  
Toru Satoh ◽  
Takanobu Yagi ◽  
Yoichi Sawada ◽  
Kenji Sugiu ◽  
Yu Sato ◽  
...  
Keyword(s):  
Intracranial Aneurysms ◽  
Computed Tomographic Angiography ◽  
Computed Tomographic ◽  
Unruptured Intracranial Aneurysms ◽  
In Series ◽  
Group A ◽  
Bleb Formation ◽  
Independent Variable ◽  
Group B ◽  
Tomographic Angiography

Abstract The mechanism of bleb formation in unruptured intracranial aneurysms (UIAs) remains unclear. This study aimed to investigate the association between peri-aneurysmal contact (PAC) and bleb formation. Forty-five aneurysms were classified depending on the presence of blebs and PAC using computed tomographic angiography and magnetic resonance imaging. Aneurysmal hemodynamics were assessed using computational fluid dynamics. The independent variables associated with bleb formation were statistically assessed. Fourteen aneurysms (31.1%) had blebs, all of which were located at the site of PAC (group A). Thirty-one aneurysms (68.9%) had no bleb, of which 13 had a PAC (group B) and 18 had no PAC (group C). PAC was the only independent variable associated with bleb formation (p < 0.05). Aneurysmal volumes were significantly higher in group A, followed by groups B and C in series. Aneurysmal wall shear stress (WSS) tended to be lowest in group A, followed by groups B and C in series. The maximum WSS at the blebs was only 17% of the maximum WSS at the aneurysmal domes. This study demonstrated that bleb formation in UIAs was associated with the establishment of PAC during their growth, which may have more detrimental effects on bleb formation than hemodynamics.

The Role of Computed Tomographic Angiography in the Diagnosis of Intracranial Aneurysms and Emergent Aneurysm Clipping

Neurosurgery ◽  
1996 ◽  
Vol 38 (3) ◽  
pp. 481-487 ◽  
Author(s):  
John N.K. Hsiang ◽  
Eisen Y. Liang ◽  
Joseph M.K. Lam ◽  
Zhu Xian-Lun ◽  
Wai S. Poon
Keyword(s):  
Intracranial Aneurysms ◽  
Computed Tomographic Angiography ◽  
Computed Tomographic ◽  
Aneurysm Clipping ◽  
Tomographic Angiography

3-Dimensional computed tomographic angiography for use of surgery planning in patients with intracranial aneurysms

2005 ◽  
Vol 147 (10) ◽  
pp. 1045-1053 ◽  
Author(s):  
I. Pechlivanis ◽  
K. Schmieder ◽  
M. Scholz ◽  
M. König ◽  
L. Heuser ◽  
...  
Keyword(s):  
Intracranial Aneurysms ◽  
Computed Tomographic Angiography ◽  
Surgery Planning ◽  
3 Dimensional ◽  
Computed Tomographic ◽  
Tomographic Angiography

scholarly journals The Accuracy and Usefulness of 3D-DSA and 3D-CT Angiography for Cerebral Aneurysms

2001 ◽  
Vol 7 (1_suppl) ◽  
pp. 181-186 ◽  
Author(s):  
F. Ishida ◽  
K. Kawaguchi ◽  
M. Mizuno ◽  
T. Hoshino ◽  
K. Murao ◽  
...  
Keyword(s):  
Intracranial Aneurysms ◽  
Three Dimensional ◽  
Cerebral Aneurysms ◽  
Computed Tomographic Angiography ◽  
Dissecting Aneurysm ◽  
Digital Subtraction ◽  
Computed Tomographic ◽  
3D Ct Angiography ◽  
The Difference ◽  
Tomographic Angiography

For evaluation of intracranial cerebral aneurysms, three-dimensional (3D) digital subtraction angiography (DSA) and 3D-computed tomographic angiography (CTA) were demonstrated in fifteen patients. The diagnostic accuracy of preoperative 3DCTA is equal to that of 3D-DSA except for the case with a dissecting aneurysm. The virtual images of 3D-CTA were well correlated with surgical findings. In endovascular treatment of intracranial aneurysms, 3D-DSA had an obvious advantage in obtaining the best working angle of the C-arm. The major branches originating from the dome were depicted on 3D-DSA in two cases that could not be judged on 3D-CTA. The aim of the present study was to verify the difference between 3D-DSA and 3D-CTA for evaluation of intracranial aneurysms.

scholarly journals Diagnostic Validity of 3D-Computed Tomographic Angiography in Spontaneous Subarachnoid Haemorrhage

2019 ◽  
Vol 5 (1) ◽  
pp. 47-52
Author(s):  
Nur Mohammad ◽  
Jalal Uddin Mohammad Rumi ◽  
Sadia Jabeen Khan ◽  
Kalim Uddin ◽  
Patoary Mohammed Faruque
Keyword(s):  
Intracranial Aneurysm ◽  
Positive Predictive Value ◽  
Subarachnoid Haemorrhage ◽  
Negative Predictive Value ◽  
Predictive Value ◽  
Intracranial Aneurysms ◽  
Computed Tomographic Angiography ◽  
Diagnostic Validity ◽  
Computed Tomographic ◽  
Tomographic Angiography

Background: Diagnostic validity of different tests for the detection of spontaneous subarachnoid haemorrhage is an important issue. Objectives: The purpose of the present study was to validate 3D-Computed tomographic angiography in spontaneous subarachnoid haemorrhage. Methodology: This cross-sectional study was carried out in the Department of Neurosurgery and Cath Lab of DMCH in collaboration with private diagnostic centre from September 2013 to February 2015 for a period of six (06) months. Adult patients diagnosed as a case of spontaneous SAH based on clinical features and confirmed by plain CT evidence of subarachnoid blood were included as study population. Patients having current history of trauma, poor clinical grade and agitated patient, patient with renal insufficiency, known allergy to iodinated contrast agent and patients who were not willing participate in the study were excluded from this study. Then both CT angiography and DSA were performed to detect cause of bleeding and to make a treatment planning. In this study DSA was considered as reference standard for evaluation of CTA. Sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of CTA were calculated per patient basis and per aneurysmal basis. Result: A total number of 37 patients presented with spontaneous subarachnoid haemorrhage were recruited for this study. The mean age of patients was 58.53±7.54 years. Sensitivity and specificity in depicting intracranial aneurysms were, 93.75% and 100% respectively on a per-patient basis. Positive predictive value and negative predictive value of CTA are 100% and 71.43% respectively. CTA had shown 94.59% accuracy in detection of intracranial aneurysm. Sensitivity and specificity in depicting intracranial aneurysms were 94.74% and 100% respectively on a per-aneurysm basis. Positive predictive value and negative predictive value of CTA are 100% and 71.43% respectively. CTA had shown 95.35% accuracy in detection of intracranial aneurysm. Conclusion: In conclusion CTA has high detection capacity of aneurysm among spontaneous subarachnoid haemorrhage patients. Journal of National Institute of Neurosciences Bangladesh, 2019;5(1): 47-52

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