scholarly journals Use of antioxidants supplementation on developmental outcomes in children with Down Syndrome - a systematic review and meta-analyses

Abstract The authors have requested that this preprint be withdrawn due to erroneous posting.

Author(s):  
Yasmin Souza Silva ◽  
Luciana Lane Gomes Da Silva ◽  
Wellington Carlos Da Silva ◽  
Agrinazio Geraldo Nascimento Neto ◽  
Thalita De Sousa Pereira ◽  
...  

Introduction: Down syndrome is a genetic condition arising from three chromosomal abnormalities, namely trisomy 21 (the most well-known); translocation, and/or mosaicism. This chromosome change occurs in the formation of the fetus, in more detail at the time of cell division, which will characterize the signs and symptoms of the syndrome. Objective: The purpose of this article is to research the main scientific findings in the last 10                years regarding physical therapy treatments, to verify the best techniques and their respective results, and to address the role of physiotherapy in the development of children with Down syndrome. Methods: The research only included studies published in the period from 2009 to 2019, systematic review articles and limited the Portuguese and English languages ​​were excluded, excluding all incomplete articles, duplications, abstracts that did not address, and those works that do not have a scientific basis. Results: In this systematic review, it can be seen that the main research results were disseminated and stored in databases (SciELO, Medline, and LILACS), focusing on the study of and DS patients, specifical children in early childhood. There are few studies on down syndrome in adults. Another important aspect is the concentration of research in the field of sports physiotherapy, few studies have focused on other areas of physiotherapy, such as respiratory, cardiovascular, and cognitive physiotherapy, which go in the opposite direction. Conclusion: Physiotherapy for patients with DS can improve the quality and life expectancy of these individuals, but the needs of patients with this syndrome involve some physical, physiological and psychological aspects and require the attention of a multidisciplinary team.


2019 ◽  
Vol 79 (7) ◽  
pp. 684-698 ◽  
Author(s):  
Falah Alhajraf ◽  
Deborah Ness ◽  
Abdul Hye ◽  
Andre Strydom

2020 ◽  
Vol 45 (2) ◽  
pp. 158-173
Author(s):  
Moreno-Garcia Gemma ◽  
Monteagudo-Chiner Pablo ◽  
Alberto Cabedo-Mas

2020 ◽  
pp. 174462952097007
Author(s):  
Marina Lummertz Magenis ◽  
Wanessa de Faveri ◽  
Kamila Castro ◽  
Gabriele Carra Forte ◽  
Antonio Jose Grande ◽  
...  

Several conditions related to serious difficulty in initiating and maintaining breastfeeding in neonates with Down syndrome are described in the literature. This study aimed to investigate the frequency of breastfeeding in neonates with Down syndrome, as well as the reasons for not breastfeeding, through a systematic literature review by searching MEDLINE via PubMed, Cochrane Library, Scopus, Embase via Elsevier, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases. Sixteen studies were included with a total sample size of 2022 children with Down syndrome. The frequency of exclusive breastfeeding was 31.6–55.4%, with five studies reporting breastfeeding for longer than 6 months. Breastfeeding from birth was present for 48–92.5% of the children with Down syndrome in six studies. Two studies reported that around 50% and 23.3% of the children with Down syndrome were never breastfed, and rates of breastfeeding in infants with Down syndrome were lower than those in controls in three studies. The reasons for not breastfeeding or cessation of breastfeeding were associated with Down syndrome-specific challenges, maternal reasons, and healthcare aspects.


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