scholarly journals Preoperative Prediction of The Operability of Pancreatic Carcinoma

Author(s):  
Wael Abdalla ◽  
Tarek Ezzet Abdellatif ◽  
Khaled Safwat ◽  
Hazem Hakim Elmenshawy ◽  
Sameh Naguib

Abstract This work discussed the best diagnostic modility for early detection of pancreatic cancer compared to final diagnosis reached by histopathological examination. The present study was constructed by doing imaging modalities computed tomography (CT) and endoscopic ultrasonography (EUS) on 24 patients admitted to surgery department in the faculty of medicine with suspected pancreatic malignancy. As regard masses diameters detected by each modality, EUS was found to be superior to CT in detection of masses less than 20mm in diameter. According to the mass nature, those found in the head region tended to be malignant more frequently than the body and tail, Moreover, solid heterogeneous masses also were more likely to be malignant than the cystic ones as detected by the imaging modalities, with higher accuracy of EUS than with CT. EUS showed more accurate information as regards lymph node involvement and vascular invasion than CT. All of which affected the assessment of resectability of pancreatic masses. On head-to-head comparison, EUS appeared to perform better than CT scan in respect to nodal staging. Based on these results, we conclude that EUS staging should be the standard of care along with state of the art CT scan for the preoperative evaluation of patients with pancreatic cancer. However, large, prospective, multicenter studies directly comparing the accuracy of linear EUS vs. new generation CT scanners are still needed.

JMS SKIMS ◽  
2017 ◽  
Vol 20 (1) ◽  
pp. 41-43
Author(s):  
Abdul Rasheed Rather ◽  
Shazia Bashir ◽  
Ather Hafiz Khan ◽  
Ashfaq Ul Hassan ◽  
Mohsin Ul Rasool ◽  
...  

Struma ovarii is a rare tumor of ovary which accounts for 1% of all ovarian tumors and 3% 0f all dermoid tumors. It belongs to the group of monodermal teratomas. We present a case of struma ovarii in a 55 year old women who presented with symptoms of pain in lower abdomen and loss of appetite for the last one month. Radiological investigations including USG, CT scan and MRI revealed a complex right adnexal lesion. Final diagnosis of struma ovarii was made on histopathological examination which revealed colloid filled thyroid follicles lined by cuboidal epithelium. JMS 2017; 20(1):41-43


2019 ◽  
Vol 6 (11) ◽  
pp. 4144
Author(s):  
Subramaniam Swaminathan ◽  
Jebin Joseph ◽  
Arun Kumar

Schwannomas are neurogenic, benign, well circumscribed tumors arising from schwann cells. Schwann cells are neural originating cell. These are either sporadic or inherited with sporadic being most common. In about 3% of patients, association with neuro-fibromatosis 2 gene is documented. Primary mesenteric schwannoma is extremely rare with establishing a pre-operative diagnosis almost impossible. Imaging modalities including computed tomography as well as MRI fails to make a diagnosis due to the non-specific characteristics. Surgery is curative with histopathological examination and immunostaining establishing the final diagnosis post-operatively. Immunostaining helps in differentiating it from other conditions such as gastro-intestinal stromal tumors as well as malignancies. Rarity of this condition make this case report of a 32-year-old male unique.


1995 ◽  
Vol 108 (4) ◽  
pp. A392
Author(s):  
C. Sperti ◽  
C. Pasquali ◽  
R. Polverosi ◽  
I. Castellaro ◽  
S. Pedrazzoli

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 14137-14137
Author(s):  
R. Epelbaum ◽  
R. Bar-Shalom ◽  
Z. Keidar ◽  
D. Gaitini ◽  
R. Haddad ◽  
...  

14137 Background: The goal of the study was to review our clinical experience with 18F-FDG PET/CT in patients (pts) with suspected recurrence of pancreatic cancer. Methods: Nine pts (M/F=3/6, age 47–73y) with increasing levels of CA 19–9 and/or CEA during follow-up and negative or equivocal CT scan were included. Seven pts were asymptomatic and 2 pts had mild abdominal pain. Previous treatment included pancreaticoduodenectomy in 6 pts and distal pancreatectomy in 3 pts. Adjuvant chemoradiation was given to 5 pts as well. Tumor markers first increased 2 to 14 months after the operation. CT scan was done within one month in all pts, and found to be normal in 6 pts and equivocal in 3 pts. PET/CT was performed one months (5 pts), 2 months (2 pts) and 3 months (2 pts) later. However, the last 2 pts had a 2nd normal CT scan 1–2 months after the PET/CT. A final diagnosis of recurrence was confirmed by histopathology or by further clinical and radiologic follow up. Results: Of the 9 pts, 8 exhibited PET/CT findings consisted with recurrent cancer. Increased tracer uptakes with abnormal findings on CT were found in 5 pts with CT scan previously defined as normal ( 2 in tumor bed and 3 in distant sites, 1 liver, 1 liver and lymph nodes, 1 abdominal wall). PET/CT was also positive in 3 pts with equivocal CT findings (2 tumor bed, 1 liver with a new unsuspected positive site in tumor bed). Chemotherapy (followed by surgery in 1 pt and by radiation therapy in 1 pt, both with local recurrence) was instituted in 7 pts following PET/CT findings. One pt underwent resection of an isolated abdominal recurrence. After a median follow-up of 7 months (range, 4 -27 m) 4 pts had died of disease, 2 are alive with progressing disease, one has responded to treatment (PET/CT became normal) and one is undergoing ghemotherapy. One of the 9 pts had a false negative PET/CT test, as abdominal spread was later found by an additional CT scan, still with a 2nd negative PET/CT image. Conclusions: PET/CT is a useful tool for detecting recurrent pancreatic cancer, and can demonstrate recurrence site when CT is non-diagnostic. Its impact on clinical management and treatment results should be further evaluated. No significant financial relationships to disclose.


1999 ◽  
Vol 82 (S 01) ◽  
pp. 171-175 ◽  
Author(s):  
D. Ebert ◽  
M. Langer ◽  
P. Uhrmeister

SummaryThe endovascular treatment of abdominal aortic aneurysms has generated a great deal of interest since the early 1990s, and many different devices are currently available. The procedure of endovascular repair has been evaluated in many institutions and the different devices are compared. The first results were encouraging, but complications like endoleak, dislocation or thrombosis of the graft occurred. By the available devices the stent application is only promising, if the known exclusion criteria are strictly respected. Therefore a careful preinterventional assessment of the patient by different imaging modalities is necessary. As the available results up to now are preliminary and the durability of the devices has to be controlled, multicenter studies are required to improve the devices and observe their long- term success in the exclusion of abdominal aortic aneurysms.


Author(s):  
Bhawana Pant ◽  
Sanjay Gaur ◽  
Prabhat Pant

F.NA.C has been used for ages as a safe and economical tool for fast preoperative diagnosis of parotid tumors. It has certain pitfall which sometimes leads to misdiagnosis and consequently it may have affect on treatment of the tumors. Keeping in view of the diverse classification of parotid tumors’ information from cytology should be combined with radiology as well as clinical diagnosis. Aim: To discuss some cases where there was discrepancy between cytological diagnosis and histopathological result and also suggest measures to improve the efficacy of F.N.A.C. Material and methods: The study includes 50 cases of parotid tumours who presented to the  department of ENT at Government medical college Haldwani which is a tertiary referral centre during 2009 to 2016. Only adult patients were included and inflammatory swelling were excluded from the study. All patients evaluated  Contrast enhanced computerized tomography(CECT) and  Magnetic resonance imaging (MRI) followed by Fine needle aspiration cytology .Preoperative diagnosis was made upon the findings of the above investigations and different types of  parotid surgeries  were done. . Final diagnosis was made on  histopathological  examination. Result :The most common tumour  came out to be pleomorphic adenoma (23 cases-46%) followed by mucoepidermoid carcinoma(12cases-24%). In ten  cases there was no clear cut  association between cytological diagnosis and final histopathological diagnosis. Conclusion: FNAC is highly sensitive and specific technique for diagnosis of many salivary gland swellings. FNAC can be used preoperatively to avoid unnecessary surgery and biopsy. Details of clinical information and radiologic features may help the pathologist to arrive at the appropriate diagnosis and reduce false interpretation. Pitfalls may also occur with improper technique of FNAC which can be overcome by proper caution.


ORL ro ◽  
2016 ◽  
Vol 1 (1) ◽  
pp. 6-12
Author(s):  
Iulian Damian ◽  
Gheorghe-Ionel Comșa

Preoperative evaluation of maxillary sinus anatomy is very important to avoid surgical complications due to close anatomical relations between the sinus and the posterior maxillary teeth and/or edentulous alveolar ridge. Posterior superior alveolar artery is a branch of the maxillary artery and provides the vascularization of the lateral sinus wall and underlying mucosa. Maxillary artery branches should be taken into consideration during sinus lifting procedures and bone augmentation due to increased risk of bleeding by damaging the artery during the osteotomy. Computed tomography (CT) explores three-dimensional anatomic structures and provides complex and accurate information about them. Cone Beam Computed Tomography (CBCT) offers an accurate view of the teeth and surrounding structures at high resolution, despite low-dose radiation used. In this study, the incidence of anatomical variations and sinus pathology were assessed using CBCT. The aim is to evaluate the presence of sinus pathology (sinus mucosal thickening, oro-antral communications, sinus tumors, cysts, polyps), presence and position of the posterior superior alveolar artery. These issues are important because they are about the limits of the dental implants in the posterior maxillary area. The presence of sinus pathology and anatomical variations may predispose to complications and even failures of implantation therapy.  


2018 ◽  
Vol 64 (2) ◽  
pp. 228-233
Author(s):  
Vladimir Lubyanskiy ◽  
Vasiliy Seroshtanov ◽  
Ye. Semenova

The aim: To analyze results of surgical treatment of patients with chronic pancreatitis (CP) and to assess the causes of pancreatic cancer after surgical treatment. Materials and methods: 137 patients had duodenum-preserving resections of the pancreas. Results: In the histological examination of the pancreas it was established that the growth of fibrous tissue was registered in patients with CP., which in 19 (13.8%) almost completely replaced the acinar tissue. In the long term after the operation from 6 months to 2 years in 8 patients (5.8%) pancreatic cancer was detected. Possible causes of tumor origin were analyzed, the value of preservation of ductal hypertension, which affects the state of the duct’s epithelium, was established. The most commonly used for treatment of chronic pancreatitis the Frey surgery removed pancreatic hypertension but in two patients during the operation an insufficient volume of the pancreatic head was reconstructed. In the case of the abandonment of a large array of fibrous tissue, local hypertension was retained in the region of the ductal structures of the head, which led to the transformation of the duct epithelium. An essential factor in the problem of the preservation of pancreatic hypertension were the stenosis of pancreatic intestinal anastomoses, they arose in the long term in 4 operated patients. With stenosis of anastomosis after duodenum-preserving resection both the hypertension factor and the regeneration factor could be realized, which under certain circumstances might be significant. Conclusion: After resection of the pancreas for CP cancer was diagnosed in 5.8% of patients. The main method of preventing the risk of cancer was performing the Frey surgery for CP eliminating pancreatic hypertension in the head region of the pancreas. Diagnosis of stenosis in the late period after resection of the pancreas was an important element in the prevention of recurrence of cancer since a timely reconstructive operation could improve the drainage of duct structures.


2021 ◽  
pp. 014556132110221
Author(s):  
Bouatay Rachida ◽  
Ons Kharrat ◽  
Wiem Boughzala ◽  
Seifeddine Ben Hammouda ◽  
Nouha Ben Abdeljelil ◽  
...  

We report the case of a 10-year-old girl with a painless slowly growing mass that had developed over the course of 2 years in the left submandibular area. Physical examination revealed a firm painless submandibular mass with no other associated signs. Ultrasound graphics were in favor of a sebaceous cyst. Fine-needle aspiration and magnetic resonance images (MRI) concluded to a pleomorphic adenoma of the submandibular gland. The patient underwent left submandibulectomy. Histopathological examination confirmed the diagnosis of pleomorphic adenoma arising from the submandibular gland. The postoperative course was uneventful. Pleomorphic adenoma of the submandibular gland represents a diagnostic and therapeutic dilemma in children. Preoperative evaluation, including MRI and fine-needle aspiration, is recommended. Total submandibulectomy is also recommended to minimize recurrences and to avoid malignant transformation.


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