scholarly journals Maternal Psychological Distress, Education, Household Income, and Congenital Heart Defects: A Prospective Cohort Study from The Japan Environment and Children’s Study Running Title Maternal Psychological Distress and Congenital Heart Defects

2021 ◽  
Author(s):  
Yasuaki Saijo ◽  
Eiji Yoshioka ◽  
Yukihiro Sato ◽  
Hiroshi Azuma ◽  
Yusuke Tanahashi ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Cohort Study ◽  
Psychological Distress ◽  
Congenital Heart Defects ◽  
Household Income ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Maternal Education ◽  
Heart Defects ◽  
Maternal Psychological Distress

Abstract Background: The influence of maternal psychological distress on infant congenital heart defects (CHDs) has not been thoroughly investigated. Furthermore, there have been no reports on the combined effect of maternal psychological distress and socioeconomic status on infant CHDs. This study aimed to examine whether maternal psychological distress, socioeconomic status, and their combinations were associated with CHD.Methods: We conducted a prospective cohort study using data from the Japan Environment and Children’s Study, which recruited pregnant women between 2011 and 2014. Maternal psychological distress was evaluated using the Kessler Psychological Distress Scale in the first trimester, while maternal education and household income were evaluated in the second and third trimesters. The outcome of infant CHD was determined using the medical records at 1 month of age and/or at birth. Crude and adjusted logistic regression analyses were performed to evaluate the association between maternal psychological distress and education and household income on infant CHD.Results: A total of 93,643 pairs of mothers and infants were analyzed, with 1.1% of infants having CHDs. Maternal psychological distress had a significantly higher odds ratio in the crude analysis but not in the adjusted analysis, while maternal education and household income were statistically insignificant. In the analysis of the combination variable of lowest education and psychological distress, the trend for p was statistically significant in the crude and adjusted analyses.Conclusions: The combination of maternal psychological distress and lower education may be a possible indicator of infant CHD.

scholarly journals Maternal psychological distress, education, household income, and congenital heart defects: a prospective cohort study from the Japan environment and children’s study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yasuaki Saijo ◽  
Eiji Yoshioka ◽  
Yukihiro Sato ◽  
Hiroshi Azuma ◽  
Yusuke Tanahashi ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Cohort Study ◽  
Psychological Distress ◽  
Congenital Heart Defects ◽  
Household Income ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Maternal Education ◽  
Heart Defects ◽  
Maternal Psychological Distress

Abstract Background The influence of maternal psychological distress on infant congenital heart defects (CHDs) has not been thoroughly investigated. Furthermore, there have been no reports on the combined effect of maternal psychological distress and socioeconomic status on infant CHDs. This study aimed to examine whether maternal psychological distress, socioeconomic status, and their combinations were associated with CHD. Methods We conducted a prospective cohort study using data from the Japan Environment and Children’s Study, which recruited pregnant women between 2011 and 2014. Maternal psychological distress was evaluated using the Kessler Psychological Distress Scale in the first trimester, while maternal education and household income were evaluated in the second and third trimesters. The outcome of infant CHD was determined using the medical records at 1 month of age and/or at birth. Crude- and confounder-adjusted logistic regression analyses were performed to evaluate the association between maternal psychological distress and education and household income on infant CHD. Results A total of 93,643 pairs of mothers and infants were analyzed, with 1.1% of infants having CHDs. Maternal psychological distress had a significantly higher odds ratio in the crude analysis but not in the adjusted analysis, while maternal education and household income were statistically insignificant. In the analysis of the combination variable of lowest education and psychological distress, the P for trend was statistically significant in the crude and multivariate model excluding anti-depressant medication, but the significance disappeared in the full model (P = 0.050). Conclusions The combination of maternal psychological distress and lower education may be a possible indicator of infant CHD.

A prospective cohort study on association of first-trimester serum biomarkers and risk of isolated fetal congenital heart defects

Biomarkers ◽  
2021 ◽  
pp. 1-5
Author(s):  
Mohammad Nasir Hematian ◽  
Kamran Hessami ◽  
Shirin Torabi ◽  
Maasoumeh Saleh ◽  
Behnaz Nouri ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
First Trimester ◽  
Serum Biomarkers

scholarly journals VP21.05: Prevalence of growth restriction at birth for newborns with congenital heart defects: a population‐based prospective cohort study

2021 ◽  
Vol 58 (S1) ◽  
pp. 184-184
Author(s):  
A. Ghanchi ◽  
M. Rahshenas ◽  
D. Bonnet ◽  
N. Derridj ◽  
N. Lelong ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
Population Based ◽  
Growth Restriction

scholarly journals Prognostic role of brain natriuretic peptide in children of the first year of life with congenital heart defects: a prospective cohort study

2020 ◽  
Vol 1 (2) ◽  
pp. 10-17
Author(s):  
Irina V. Vakhlova ◽  
Ekaterina V. Saperova
Keyword(s):  
Cohort Study ◽  
Brain Natriuretic Peptide ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
First Year ◽  
Prognostic Role ◽  
First Year Of Life

Background. Congenital heart defects (CHD) are the most common type of developmental anomalies in children. At present the early diagnosis of congestive heart failure (CHF) and CHF-associated pathologic conditions is becoming increasingly important for optimization of protocols for following up pediatric patients in the primary health care settings.Objective. The study aimed at determining the prognostic role of brain natriuretic peptide (BNP) as a diagnostic marker of CHF progression and development of CHF-associated pathological conditions in babies with CHD during the first year of life.Methods. A prospective cohort study was carried out in a total of 114 children of the first year of life. The main study group was comprised of 61 children with confirmed diagnosis of CHD, and the control group of 53 health status group I–IIA children without CHD.Results. Diagnostic role of BNP elevation > 30 pg/mL was determined. At this BNP level the risk for developing stage 2A CHF increased 7-fold (OR 7.5 [1.8–31.5]), for developing functional class (FC) 2 CHF — nearly 5-fold (OR 4.6 [1.3–16.0]), and for FC 3 CHF such risk increased 9-fold (OR 9.2 [2.3–36.1]). Our results demonstrated that the BNP level measurements can be used in clinical practice to determine the likelihood of persistence of symptoms of perinatal CNS injuries during the first year of life (OR 7.6 [1.7–34.5]) and protein and energy deficit (PED) (OR 9.5 [2.5–35.5]) in children with CHD.

Prevalence of growth restriction at birth for newborns with congenital heart defects: A population-based prospective cohort study

2021 ◽  
Vol 13 (4) ◽  
pp. 275
Author(s):  
A. Ghanchi. ◽  
M. Rahshenas ◽  
D. Bonnet ◽  
N. Derridj ◽  
N. LeLong ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
Population Based ◽  
Growth Restriction

scholarly journals Prognostic role of brain natriuretic peptide in children of the first year of life with congenital heart defects: a prospective cohort study

2020 ◽  
Vol 1 (2) ◽  
pp. 10-17
Author(s):  
Irina V. Vakhlova ◽  
Ekaterina V. Saperova
Keyword(s):  
Cohort Study ◽  
Brain Natriuretic Peptide ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
First Year ◽  
Prognostic Role ◽  
First Year Of Life

Background. Congenital heart defects (CHD) are the most common type of developmental anomalies in children. At present the early diagnosis of congestive heart failure (CHF) and CHF-associated pathologic conditions is becoming increasingly important for optimization of protocols for following up pediatric patients in the primary health care settings.Objective. The study aimed at determining the prognostic role of brain natriuretic peptide (BNP) as a diagnostic marker of CHF progression and development of CHF-associated pathological conditions in babies with CHD during the first year of life.Methods. A prospective cohort study was carried out in a total of 114 children of the first year of life. The main study group was comprised of 61 children with confirmed diagnosis of CHD, and the control group of 53 health status group I–IIA children without CHD.Results. Diagnostic role of BNP elevation > 30 pg/mL was determined. At this BNP level the risk for developing stage 2A CHF increased 7-fold (OR 7.5 [1.8–31.5]), for developing functional class (FC) 2 CHF — nearly 5-fold (OR 4.6 [1.3–16.0]), and for FC 3 CHF such risk increased 9-fold (OR 9.2 [2.3–36.1]). Our results demonstrated that the BNP level measurements can be used in clinical practice to determine the likelihood of persistence of symptoms of perinatal CNS injuries during the first year of life (OR 7.6 [1.7–34.5]) and protein and energy deficit (PED) (OR 9.5 [2.5–35.5]) in children with CHD.

scholarly journals Prognostic role of brain natriuretic peptide in children of the first year of life with congenital heart defects: a prospective cohort study

2020 ◽  
Vol 1 (2) ◽  
pp. 10-17
Author(s):  
Irina V. Vakhlova ◽  
Ekaterina V. Saperova
Keyword(s):  
Cohort Study ◽  
Brain Natriuretic Peptide ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
First Year ◽  
Prognostic Role ◽  
First Year Of Life

Background. Congenital heart defects (CHD) are the most common type of developmental anomalies in children. At present the early diagnosis of congestive heart failure (CHF) and CHF-associated pathologic conditions is becoming increasingly important for optimization of protocols for following up pediatric patients in the primary health care settings.Objective. The study aimed at determining the prognostic role of brain natriuretic peptide (BNP) as a diagnostic marker of CHF progression and development of CHF-associated pathological conditions in babies with CHD during the first year of life.Methods. A prospective cohort study was carried out in a total of 114 children of the first year of life. The main study group was comprised of 61 children with confirmed diagnosis of CHD, and the control group of 53 health status group I–IIA children without CHD.Results. Diagnostic role of BNP elevation > 30 pg/mL was determined. At this BNP level the risk for developing stage 2A CHF increased 7-fold (OR 7.5 [1.8–31.5]), for developing functional class (FC) 2 CHF — nearly 5-fold (OR 4.6 [1.3–16.0]), and for FC 3 CHF such risk increased 9-fold (OR 9.2 [2.3–36.1]). Our results demonstrated that the BNP level measurements can be used in clinical practice to determine the likelihood of persistence of symptoms of perinatal CNS injuries during the first year of life (OR 7.6 [1.7–34.5]) and protein and energy deficit (PED) (OR 9.5 [2.5–35.5]) in children with CHD.

scholarly journals Academic Achievement Among Children with Congenital Heart Defects in Arkansas

2020 ◽  
Vol 5 (5) ◽  
Author(s):  
Suman Maity ◽  
Nahed El-hassan ◽  
Anthony Goudie ◽  
Jeffrey R Kaiser ◽  
Wendy N Nembhard
Keyword(s):  
Birth Weight ◽  
Congenital Heart Defects ◽  
Gestational Age ◽  
Congenital Heart ◽  
Maternal Education ◽  
Heart Defects ◽  
Birth Certificate ◽  
Educational Performance ◽  
Negatively Associated ◽  
Race Ethnicity

Children with congenital heart defects (CHD) have impaired cognitive development. The objective was to determine if children with CHDs differed in academic performance during elementary and middle school years from children without CHDs. Data from the state birth defects registry, Arkansas Reproductive Health Monitoring System (ARHMS), birth certificate records, and achievement test-scores (grades 3-8) from the Arkansas Department of Education were linked using unique identifiers for children born between 2000-2011 in Arkansas. Cases were identified using 6-digit British Paediatric Association codes and matched controls were assigned from birth certificate data. Proficiency (yes/no) on achievement tests was determined using standard thresholds per grade. Data were stratified based on sex, gestational age, and birth weight. Odds ratios (OR) and 95% confidence intervals (CI) were calculated from multivariate logistic regression adjusting for maternal education level and age, race/ethnicity, and infant sex. A total of 3,730 children with CHDs and 7,385 children without CHDs were evaluated. Children with CHD were less likely to be proficient in early elementary school grades for mathematics (3rd: OR=0.72, 95% CI: 0.59, 0.87; 4th: OR=0.77, 95% CI: 0.62, 0.95) and literacy (3rd: OR=0.75, 95% CI: 0.63, 0.89; 4th: OR=0.72, 95% CI: 0.58, 0.90). The trend of being less proficient associated with CHD remained mostly consistent with sex, gestational age, and birth weight. In multivariate analysis, CHD was negatively associated with being proficient in mathematics and literacy. Maternal education (1-3 years beyond high school) was positively associated with test proficiency. Additionally, non-Hispanic (NH) black children had lower odds of being proficient compared to NH white children. Educational performance was negatively associated with CHD in early elementary grades; there was no difference in later grades. However, larger sample sizes in later grades are necessary for reliable estimates. Maternal education and race/ethnicity were significant factors associated with childhood educational performance.

scholarly journals Prevalence of congenital heart defects in neuroblastoma patients: a cohort study and systematic review of literature

2008 ◽  
Vol 168 (9) ◽  
pp. 1081-1090 ◽  
Author(s):  
Klaartje van Engelen ◽  
Johannes H. M. Merks ◽  
Jan Lam ◽  
Leontien C. M. Kremer ◽  
Manouk Backes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cohort Study ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Review Of Literature

scholarly journals Intake of sucrose-sweetened soft beverages during pregnancy and risk of congenital heart defects (CHD) in offspring: a Norwegian pregnancy cohort study

2019 ◽  
Vol 34 (4) ◽  
pp. 383-396 ◽  
Author(s):  
Maria T. Grønning Dale ◽  
Per Magnus ◽  
Elisabeth Leirgul ◽  
Henrik Holmstrøm ◽  
Håkon K. Gjessing ◽  
...  
Keyword(s):  
Cohort Study ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Pregnancy Cohort
Sign in / Sign up

Export Citation Format

Share Document