scholarly journals VP21.05: Prevalence of growth restriction at birth for newborns with congenital heart defects: a population‐based prospective cohort study

2021 ◽  
Vol 58 (S1) ◽  
pp. 184-184
Author(s):  
A. Ghanchi ◽  
M. Rahshenas ◽  
D. Bonnet ◽  
N. Derridj ◽  
N. Lelong ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
Population Based ◽  
Growth Restriction

Prevalence of growth restriction at birth for newborns with congenital heart defects: A population-based prospective cohort study

2021 ◽  
Vol 13 (4) ◽  
pp. 275
Author(s):  
A. Ghanchi. ◽  
M. Rahshenas ◽  
D. Bonnet ◽  
N. Derridj ◽  
N. LeLong ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
Population Based ◽  
Growth Restriction

A prospective cohort study on association of first-trimester serum biomarkers and risk of isolated fetal congenital heart defects

Biomarkers ◽  
2021 ◽  
pp. 1-5
Author(s):  
Mohammad Nasir Hematian ◽  
Kamran Hessami ◽  
Shirin Torabi ◽  
Maasoumeh Saleh ◽  
Behnaz Nouri ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
First Trimester ◽  
Serum Biomarkers

scholarly journals Maternal psychological distress, education, household income, and congenital heart defects: a prospective cohort study from the Japan environment and children’s study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yasuaki Saijo ◽  
Eiji Yoshioka ◽  
Yukihiro Sato ◽  
Hiroshi Azuma ◽  
Yusuke Tanahashi ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Cohort Study ◽  
Psychological Distress ◽  
Congenital Heart Defects ◽  
Household Income ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Maternal Education ◽  
Heart Defects ◽  
Maternal Psychological Distress

Abstract Background The influence of maternal psychological distress on infant congenital heart defects (CHDs) has not been thoroughly investigated. Furthermore, there have been no reports on the combined effect of maternal psychological distress and socioeconomic status on infant CHDs. This study aimed to examine whether maternal psychological distress, socioeconomic status, and their combinations were associated with CHD. Methods We conducted a prospective cohort study using data from the Japan Environment and Children’s Study, which recruited pregnant women between 2011 and 2014. Maternal psychological distress was evaluated using the Kessler Psychological Distress Scale in the first trimester, while maternal education and household income were evaluated in the second and third trimesters. The outcome of infant CHD was determined using the medical records at 1 month of age and/or at birth. Crude- and confounder-adjusted logistic regression analyses were performed to evaluate the association between maternal psychological distress and education and household income on infant CHD. Results A total of 93,643 pairs of mothers and infants were analyzed, with 1.1% of infants having CHDs. Maternal psychological distress had a significantly higher odds ratio in the crude analysis but not in the adjusted analysis, while maternal education and household income were statistically insignificant. In the analysis of the combination variable of lowest education and psychological distress, the P for trend was statistically significant in the crude and multivariate model excluding anti-depressant medication, but the significance disappeared in the full model (P = 0.050). Conclusions The combination of maternal psychological distress and lower education may be a possible indicator of infant CHD.

scholarly journals Prognostic role of brain natriuretic peptide in children of the first year of life with congenital heart defects: a prospective cohort study

2020 ◽  
Vol 1 (2) ◽  
pp. 10-17
Author(s):  
Irina V. Vakhlova ◽  
Ekaterina V. Saperova
Keyword(s):  
Cohort Study ◽  
Brain Natriuretic Peptide ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
First Year ◽  
Prognostic Role ◽  
First Year Of Life

Background. Congenital heart defects (CHD) are the most common type of developmental anomalies in children. At present the early diagnosis of congestive heart failure (CHF) and CHF-associated pathologic conditions is becoming increasingly important for optimization of protocols for following up pediatric patients in the primary health care settings.Objective. The study aimed at determining the prognostic role of brain natriuretic peptide (BNP) as a diagnostic marker of CHF progression and development of CHF-associated pathological conditions in babies with CHD during the first year of life.Methods. A prospective cohort study was carried out in a total of 114 children of the first year of life. The main study group was comprised of 61 children with confirmed diagnosis of CHD, and the control group of 53 health status group I–IIA children without CHD.Results. Diagnostic role of BNP elevation > 30 pg/mL was determined. At this BNP level the risk for developing stage 2A CHF increased 7-fold (OR 7.5 [1.8–31.5]), for developing functional class (FC) 2 CHF — nearly 5-fold (OR 4.6 [1.3–16.0]), and for FC 3 CHF such risk increased 9-fold (OR 9.2 [2.3–36.1]). Our results demonstrated that the BNP level measurements can be used in clinical practice to determine the likelihood of persistence of symptoms of perinatal CNS injuries during the first year of life (OR 7.6 [1.7–34.5]) and protein and energy deficit (PED) (OR 9.5 [2.5–35.5]) in children with CHD.

scholarly journals Prognostic role of brain natriuretic peptide in children of the first year of life with congenital heart defects: a prospective cohort study

2020 ◽  
Vol 1 (2) ◽  
pp. 10-17
Author(s):  
Irina V. Vakhlova ◽  
Ekaterina V. Saperova
Keyword(s):  
Cohort Study ◽  
Brain Natriuretic Peptide ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
First Year ◽  
Prognostic Role ◽  
First Year Of Life

Background. Congenital heart defects (CHD) are the most common type of developmental anomalies in children. At present the early diagnosis of congestive heart failure (CHF) and CHF-associated pathologic conditions is becoming increasingly important for optimization of protocols for following up pediatric patients in the primary health care settings.Objective. The study aimed at determining the prognostic role of brain natriuretic peptide (BNP) as a diagnostic marker of CHF progression and development of CHF-associated pathological conditions in babies with CHD during the first year of life.Methods. A prospective cohort study was carried out in a total of 114 children of the first year of life. The main study group was comprised of 61 children with confirmed diagnosis of CHD, and the control group of 53 health status group I–IIA children without CHD.Results. Diagnostic role of BNP elevation > 30 pg/mL was determined. At this BNP level the risk for developing stage 2A CHF increased 7-fold (OR 7.5 [1.8–31.5]), for developing functional class (FC) 2 CHF — nearly 5-fold (OR 4.6 [1.3–16.0]), and for FC 3 CHF such risk increased 9-fold (OR 9.2 [2.3–36.1]). Our results demonstrated that the BNP level measurements can be used in clinical practice to determine the likelihood of persistence of symptoms of perinatal CNS injuries during the first year of life (OR 7.6 [1.7–34.5]) and protein and energy deficit (PED) (OR 9.5 [2.5–35.5]) in children with CHD.

scholarly journals Prevalence of Growth Restriction at Birth for Newborns With Congenital Heart Defects: A Population-Based Prospective Cohort Study EPICARD

2021 ◽  
Vol 9 ◽  
Author(s):  
Ali Ghanchi ◽  
Makan Rahshenas ◽  
Damien Bonnet ◽  
Neil Derridj ◽  
Nathalie LeLong ◽  
...  
Keyword(s):  
General Population ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Population Based ◽  
Growth Restriction ◽  
Control Group ◽  
Using Data ◽  
Underlying Mechanisms ◽  
Adult Morbidity

Background and Objectives: Congenital heart defects (CHD) and growth restriction at birth are two major causes of childhood and adult morbidity and mortality. The aim of this study was to assess the overall risk of growth restriction at birth, as measured by its imperfect proxy small (< 10th percentile) for gestational age (SGA), for newborns with CHD.Methods: Using data from a population-based cohort of children born with CHD, we assessed the risk of growth restriction at birth using SGA and severe SGA (3rd percentile). To compare the odds of SGA and severe SGA across five specific major CHD, we used ordinal logistic regression using isolated, minor (non-operated) ventricular septal defect (VSD) as the control group.Results: The overall proportion of SGA for “isolated” CHD (i.e., those not associated with other anomalies) was 13% (95% CI, 12–15%), which is 30% higher than what would be expected in the general population (i.e., 10%). The risk of severe SGA was 5% (95% CI, 4–6%) as compared with the expected 3% in the general population. There were substantial differences in the risk of overall SGA and more so severe SGA across the different CHD. The highest risk of SGA occurred for Tetralogy of Fallot (adjusted OR 2.7, 95% CI, 1.3–5.8) and operated VSD (adjusted OR 2.1, 95% CI, 1.1–3.8) as compared with the control group of minor (non-operated) VSD.Conclusion: The overall risks of both SGA and severe SGA were higher in isolated CHD than what would be expected in the general population with substantial differences across the subtypes of CHD. These results may provide a clue for understanding the underlying mechanisms of the relation between alterations in fetal circulation associated with different types of CHD and their effects on fetal growth.

scholarly journals Epidemiology of Congenital Heart Defects (CHD): Results from a Prospective, Population-Based Cohort Study (EPICARD)

2017 ◽  
Vol 06 (02) ◽  
Author(s):  
Nathalie Lelong ◽  
Francois Goffinet ◽  
Babak Khoshnood ◽  
EPICARD Study Group
Keyword(s):  
Cohort Study ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Population Based

scholarly journals Impact of preterm birth on infant mortality for newborns with congenital heart defects: The EPICARD population-based cohort study

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Enora Laas ◽  
◽  
Nathalie Lelong ◽  
Pierre-Yves Ancel ◽  
Damien Bonnet ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Birth ◽  
Infant Mortality ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Population Based

Long-term neurodevelopmental outcomes of children with congenital heart defects: A prospective, population-based cohort study (EPICARD)

2021 ◽  
Vol 13 (4) ◽  
pp. 270
Author(s):  
Neil Derridj ◽  
Romain Guedj ◽  
Nathalie Lelong ◽  
Nathalie Bertille ◽  
Johanna Calderon ◽  
...  
Keyword(s):  
Cohort Study ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Population Based ◽  
Neurodevelopmental Outcomes

scholarly journals Prognostic role of brain natriuretic peptide in children of the first year of life with congenital heart defects: a prospective cohort study

2020 ◽  
Vol 1 (2) ◽  
pp. 10-17
Author(s):  
Irina V. Vakhlova ◽  
Ekaterina V. Saperova
Keyword(s):  
Cohort Study ◽  
Brain Natriuretic Peptide ◽  
Congenital Heart Defects ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Heart Defects ◽  
First Year ◽  
Prognostic Role ◽  
First Year Of Life

Background. Congenital heart defects (CHD) are the most common type of developmental anomalies in children. At present the early diagnosis of congestive heart failure (CHF) and CHF-associated pathologic conditions is becoming increasingly important for optimization of protocols for following up pediatric patients in the primary health care settings.Objective. The study aimed at determining the prognostic role of brain natriuretic peptide (BNP) as a diagnostic marker of CHF progression and development of CHF-associated pathological conditions in babies with CHD during the first year of life.Methods. A prospective cohort study was carried out in a total of 114 children of the first year of life. The main study group was comprised of 61 children with confirmed diagnosis of CHD, and the control group of 53 health status group I–IIA children without CHD.Results. Diagnostic role of BNP elevation > 30 pg/mL was determined. At this BNP level the risk for developing stage 2A CHF increased 7-fold (OR 7.5 [1.8–31.5]), for developing functional class (FC) 2 CHF — nearly 5-fold (OR 4.6 [1.3–16.0]), and for FC 3 CHF such risk increased 9-fold (OR 9.2 [2.3–36.1]). Our results demonstrated that the BNP level measurements can be used in clinical practice to determine the likelihood of persistence of symptoms of perinatal CNS injuries during the first year of life (OR 7.6 [1.7–34.5]) and protein and energy deficit (PED) (OR 9.5 [2.5–35.5]) in children with CHD.

Sign in / Sign up

Export Citation Format

Share Document