scholarly journals A case-control study on psychotropic substance use and risk of Axis I psychiatric disorders in HIV-infected gay or bisexual men in Hong Kong

2020 ◽  
Author(s):  
Chi Kei Krystal Lee ◽  
Kar Kin Albert Chung

Abstract Background: Psychotropic substance use is common in HIV-infected gay or bisexual men (GBM). This study examined the association between Axis I psychiatric disorders and active psychotropic substance use, and identified factors affecting the prevalence of psychiatric disorders in HIV-infected GBM.Methods: This is a cross-sectional case-control study taken place in an HIV clinic and community organisations serving people living with HIV or GBM in Hong Kong. Participants were 62 HIV-infected self-identified GBM who reported psychotropic substance use in the past 1 year (cases), and 55 HIV-infected self-identified GBM without psychotropic substance use in the past 1 year and had negative toxicology tests at recruitment (controls).The Chinese-bilingual Structured Clinical Interview for DSM-IV (Axis I, Patient version) was followed to establish the psychiatric diagnoses. Socio-demographic data, level of social support, HIV-related data, and pattern of psychotropic substance use were collected. Results: Cases had lower level of social support (p=0.02), more depressive disorders (AOR 3.4, 95% CI 1.3-8.7, p=0.01) and psychotic disorders (AOR 7.2, 95% CI 1.2-41, p=0.03) but not anxiety disorders. Significant difference in the prevalence of psychiatric disorders was only evident for disorders with onset after HIV diagnosis. Methamphetamine dependence (AOR 6.63, 95% CI 1.53-228.72, p<0.01), weekly methamphetamine use for 2 years or more (AOR 18.6, 95% CI 1.26-274.69, p=0.03), using methamphetamine beyond chemsex (AOR 4.76, 95% CI 1.17-19.41, p=0.03) were significant predictors for psychiatric disorders in the cases in separate logistic regression models. Duration of HIV diagnosis was a significant independent predictor in all three models. Conclusions: Active psychotropic substance use in HIV-infected gay or bisexual men was associated with a 3-fold increase in Axis I psychiatric disorders. This increase in psychiatric disorders was predicted by the severity, duration and context of methamphetamine use and the duration of HIV diagnosis.

2017 ◽  
Vol 4 (4) ◽  
Author(s):  
Sivabalan E ◽  
Arun Narayan Pradeep

Background: Suicide attempts and Psychiatric illness are interrelated in a complex and bi directional way such that either of them leaves an impact on the other. People with Psychiatric morbidity are at high risk of attempting suicide. Even though extensive research works have been done in suicide, there is a paucity of studies focusing the mentally ill attempters, especially with reference to Intent and Lethality. Hence the present study designed to study the various parameters , contributing factors and Risk factors associated with suicide attempts of patient with Axis I disorders. Aim: 1.To assess the life stressors and suicidal intent in suicide attempters with Axis I psychiatric disorders. 2. To assess the life stressors and suicidal intent in suicide attempters without Axis I psychiatric disorders. 3. Compare the life stressors and suicidal intent in suicide attempters with and without axis I disorders. Material and Methods: The study subjects of this case control study were recruited from the patients referred to the department of Psychiatry from Medicine, Surgical and Intensive care wards for Psychiatric evaluation.30 patients of attempted suicide who had Axis I diagnosis as per the ICD – 10 criteria were taken as cases and 30 age and sex matched patients were taken as controls. Results: 1.The suicidal intent is high in Suicide attempters with Axis I Disorders. 2. The lethality is high in Suicidal attempters with Axis I Disorders. 3. Stress factors play a major role in Suicide attempters with Axis I disorders.


2010 ◽  
Vol 16 (Supplement 1) ◽  
pp. A7-A7
Author(s):  
A. Ahmadi ◽  
R. Mohammadi ◽  
D. C. Schwebel ◽  
N. Yeganeh ◽  
S. Hejazi-Bazargan

2010 ◽  
Vol 55 (2) ◽  
pp. 447-450 ◽  
Author(s):  
Alireza Ahmadi ◽  
Reza Mohammadi ◽  
David C. Schwebel ◽  
Naser Yeganeh ◽  
Mehdi Hassanzadeh ◽  
...  

2010 ◽  
Vol 197 (4) ◽  
pp. 313-319 ◽  
Author(s):  
Adrienne Rivlin ◽  
Keith Hawton ◽  
Lisa Marzano ◽  
Seena Fazel

BackgroundAlthough male prisoners are five times more likely to die by suicide than men of a similar age in the general population, the contribution of psychiatric disorders is not known.AimsTo investigate the association of psychiatric disorders with near-lethal suicide attempts in male prisoners.MethodA matched case–control study of 60 male prisoners who made near-lethal suicide attempts (cases) and 60 prisoners who had never carried out near-lethal suicide attempts in prison (controls) was conducted. Psychiatric disorders were identified with the Mini International Neuropsychiatric Interview (MINI), and information on sociodemographic characteristics and criminal history was gathered using a semi-structured interview.ResultsPsychiatric disorders were present in all cases and 62% of controls. Most current psychiatric disorders were associated with near-lethal suicide attempts, including major depression (odds ratio (OR) = 42.0, 95% CI 5.8–305), psychosis (OR = 15.0, 95% CI 2.0–113), anxiety disorders (OR = 6.0, 95% CI 2.3–15.5) and drug misuse (OR = 2.9, 95% CI 1.3–6.4). Lifetime psychiatric disorders associated with near-lethal attempts included recurrent depression and psychoses. Although cases were more likely than controls to meet criteria for antisocial personality disorder, the difference was not statistically significant. Comorbidity was also significantly more common among cases than controls for both current and lifetime disorders.ConclusionsIn male prisoners, psychiatric disorders, especially depression, psychosis, anxiety and drug misuse, are associated with near-lethal suicide attempts, and hence probably with suicide.


Addiction ◽  
2008 ◽  
Vol 103 (7) ◽  
pp. 1198-1205 ◽  
Author(s):  
Lisia von Diemen ◽  
Diego Garcia Bassani ◽  
Sandra Costa Fuchs ◽  
Claudia Maciel Szobot ◽  
Flavio Pechansky

2018 ◽  
Vol 30 (2) ◽  
pp. 129-134 ◽  
Author(s):  
Tayfun Kara ◽  
Zeynep Topkarcı ◽  
Semra Yılmaz ◽  
İsmail Akaltun ◽  
Bilgen Erdoğan

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