Risk of seizures associated with antipsychotic treatment in pediatrics with psychiatric disorders: a nested case–control study in Korea

2020 ◽  
Author(s):  
Soo Min Jeon ◽  
Susan Park ◽  
Dohoon Kim ◽  
Jin-Won Kwon
Keyword(s):  
Psychiatric Disorders ◽  
Case Control Study ◽  
Case Control ◽  
Antipsychotic Treatment ◽  
Nested Case Control ◽  
Control Study

Antipsychotic treatment is associated with risk of atrial fibrillation: A nationwide nested case-control study

2017 ◽  
Vol 227 ◽  
pp. 134-140 ◽  
Author(s):  
Ruey-Hsing Chou ◽  
Li-Wei Lo ◽  
Ying-Jay Liou ◽  
Jiah-Hwang Shu ◽  
Hsiu-Chuan Hsu ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Case Control Study ◽  
Case Control ◽  
Antipsychotic Treatment ◽  
Nested Case Control ◽  
Control Study

scholarly journals Antipsychotic Discontinuation and Suicide in Schizophrenia Patients A Nested Case-Control Study

2020 ◽  
Author(s):  
Young Choi ◽  
Eun-Cheol Park
Keyword(s):  
Suicide Risk ◽  
Maintenance Treatment ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Population Based ◽  
Case Control ◽  
Suicide Mortality ◽  
Antipsychotic Treatment ◽  
Nested Case Control ◽  
Control Study

Abstract Background Schizophrenia patients have shorter life expectancy relative to that of the general population, and their suicide risk is reportedly higher. Although antipsychotic discontinuation rates are high, antipsychotic treatment has been associated with lower suicide mortality, and patients who do not use antipsychotics are at greater risk of suicide relative to those who use the medication. Furthermore, maintenance treatment with antipsychotic drugs protects schizophrenia patients from relapse. However, little is known about antipsychotic discontinuation, suicide risk, or the time during which suicide risk is highest following antipsychotic discontinuation. Therefore, this study investigated whether discontinuity of antipsychotics is associated with suicide in schizophrenia patients.Methods A population-based nested case-control study was conducted using the Korean National Health Insurance claims database (2002-2013). From the study population of 7,519 patients with the diagnosis of schizophrenia and at least one antipsychotics described, we identified 154 suicide cases and 760 matched controls. We calculated the days after last prescribed medication so that discontinuity of antipsychotics was defined. Conditional logistic regression were used to examine the association between discontinuity of antipsychotics and suicide adjusting for possible confounding covariates.Results Suicide risk was particularly high during the first thirty days after discharge after stopping antipsychotics compared with current user after adjusting all covariates (AOR: 4.667, 95% CI: 2.425–8.984).Conclusion Maintenance treatment with antipsychotics could help to reduce suicide risk. The results indicated that there is a need to monitor schizophrenia patients following antipsychotic discontinuation.

scholarly journals Risk of self-harm after the diagnosis of psychiatric disorders in Hong Kong, 2000–10: a nested case-control study

2020 ◽  
Vol 7 (2) ◽  
pp. 135-147 ◽  
Author(s):  
Yi Chai ◽  
Hao Luo ◽  
Gloria H Y Wong ◽  
Jennifer Y M Tang ◽  
Tai-Chung Lam ◽  
...  
Keyword(s):  
Hong Kong ◽  
Psychiatric Disorders ◽  
Case Control Study ◽  
Case Control ◽  
Self Harm ◽  
Nested Case Control ◽  
Control Study

Association between glycaemic control and fracture risk in diabetic patients: a nested case control study

2019 ◽  
Author(s):  
J Vavanikunnel ◽  
S Charlier ◽  
C Becker ◽  
C Schneider ◽  
SS Jick ◽  
...  
Keyword(s):  
Glycaemic Control ◽  
Fracture Risk ◽  
Case Control Study ◽  
Case Control ◽  
Diabetic Patients ◽  
Nested Case Control ◽  
Control Study
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