scholarly journals Diagnostic Impact of Immunonutritional Indices in Peripheral Arterial Disease Severity and Complexity

Author(s):  
Tahir Bezgin ◽  
Aziz İnan Çelik ◽  
Metin Çağdaş ◽  
Ferdi Kahraman ◽  
Kemal Mağden ◽  
...  

Abstract Purpose We aimed to evaluate the relationships between the severity of peripheral arterial disease (PAD) and immune-nutritional status, as quantified by the prognostic nutritional index (PNI), controlling nutritional status score (CONUT), and modified Glasgow prognostic score (mGPS). Methods and results One hundred forty-eight patients with severe lower extremity PAD diagnosed by angiography constituted the study population. All patients had at least one severe superficial femoral arterial disease (SFA). According to the presence of a chronic total occlusion in SFA (SFA CTO), the study population was divided into two groups. Patients with SFA CTO (n: 84) had a significantly lower PNI(43.4 ± 4.8 vs. 49.1 ± 4.7, p < 0.001), worse mGPS and CONUT scores than those without SFA CTO(n:64). A comparison of the three groups, those classified according to PNI tertiles (PNI ≥ 48, n:49; 43.8 < PNI < 48, n:49; PNI < 43.8, n: 50), revealed that a lower PNI was associated with the presence of a TASC C-D lesion in the femoropopliteal segment, SFA CTO, long lesion, and long CTO. Furthermore, PNI was found to be an independent predictor of SFA CTO in the logistic regression analysis. Diagnostic performance of PNI was better than mGPS and CONUT scores in ROC curve comparison. Conclusion This is the first study demonstrating the relationship between PNI and PAD severity. Our results and the prognostic value of PNI should be validated in a larger prospective cohort.

2011 ◽  
Vol 27 (1) ◽  
pp. 19-23 ◽  
Author(s):  
Minoru Ihara ◽  
Tsugiyoshi Yamazaki ◽  
Masaharu Kudo ◽  
Osamu Murai ◽  
Yoshiaki Tsukamoto

2016 ◽  
Vol 67 (16) ◽  
pp. S340-S342
Author(s):  
Tzu Chieh Lin ◽  
Chun-Yuan Chu ◽  
Wen-Hsien Lee ◽  
Po-Chao Hsu ◽  
Ho-Ming Su ◽  
...  

Pulse ◽  
2021 ◽  
pp. 1-6
Author(s):  
Taichiro Hayase

<b><i>Introduction:</i></b> The cardio-ankle vascular index (CAVI) is a well-known index to evaluate arterial stiffness and predict cardiovascular risk. <b><i>Methods:</i></b> We investigated whether CAVI can predict severity and extent of peripheral arterial disease. This study was a single-center, retrospective, observational study approved by the Ethics Committee of Yokohama Shintoshi Neurosurgical Hospital. A total of 96 patients (males, 63) with an abnormal ankle-brachial blood pressure index (ABI) of &#x3c;0.9 and who underwent extremity arteriography at our hospital from 2015 to 2018 were enrolled in this study. We defined that CAVI with a range of &#x3c;8.0 was normal. <b><i>Results:</i></b> Coronary angiography and extremity arteriography were performed for patients who had intermittent claudication and abnormal ABI. We divided the affected limbs into 3 categories: above-the-knee artery stenosis, above-the-knee artery chronic total occlusion, and only below-the-knee artery stenosis/occlusion groups. CAVI pseudonormalization was seen in 28, 76, and 19%, respectively. The above-the-knee artery stenosis and the only below-the-knee artery stenosis/occlusion groups had a high odds ratio of abnormalization of CAVI (3.1, 95% confidence interval [CI]: 1.39–7.22; <i>p</i> = 0.05, 4.56, 95% CI: 1.64–14.7). <b><i>Discussion/Conclusion:</i></b> In the presence of the above-the-knee artery chronic total occlusion, CAVI pseudonormalization was likely to be seen. The presence of CTO in the above-the-knee artery is one cause of pseudonormalized CAVI. In the range of ABI, in which stenotic lesions and obstructive lesions coexist, it may be possible to detect the existence of CTO by a combination of both ABI and CAVI.


2012 ◽  
Vol 65 (8) ◽  
pp. 726-733 ◽  
Author(s):  
Francisco J. Félix-Redondo ◽  
Daniel Fernández-Bergés ◽  
María Grau ◽  
José M. Baena-Diez ◽  
José M. Mostaza ◽  
...  

2020 ◽  
Vol 7 ◽  
Author(s):  
Romaric Loffroy ◽  
Nicolas Falvo ◽  
Christophe Galland ◽  
Léo Fréchier ◽  
Frédérik Ledan ◽  
...  

Over the last decade, intravascular ultrasound (IVUS) has emerged as a useful adjunctive tool to angiography in an increasing number of catheter-based procedures for peripheral arterial disease (PAD). IVUS catheters offer accurate cross-sectional imaging of arterial vessels with high dimensional accuracy and provide accurate information about lesion morphology. IVUS enables assessment of the plaque morphology, vessel diameter, and the presence of arterial dissections. Furthermore, IVUS is able to properly guide the best choice of appropriate percutaneous transluminal angioplasty (PTA) technique, guide the delivery of different devices, and assess the immediate result of any endovascular intervention. In the present review, the role of IVUS for PAD will be discussed, specifically the applications of IVUS technology during interventional procedures including PTA, stent sizing, crossing total occlusion, assessing residual narrowing and stent apposition and expansion, and atherectomy. Future perspectives of IVUS-guided treatments and cost-effectiveness of the systematic use of IVUS during endovascular interventions will be also discussed.


2006 ◽  
Vol 39 (3) ◽  
pp. 44
Author(s):  
WILLIAM E. GOLDEN ◽  
ROBERT H. HOPKINS

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