scholarly journals Safe return to elective surgery following a COVID-19 outbreak: an observational study

2021 ◽  
Author(s):  
Akihiro Aoyama ◽  
Hiroshi Yamazaki ◽  
Atsushi Yoshida ◽  
Hayato Maruoka ◽  
Seiko Nasu ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Elective Surgery ◽  
Clinical Information ◽  
Chest Ct ◽  
Single Institution ◽  
Chain Reaction ◽  
Chest Computed Tomography ◽  
Surgical Services ◽  
Admission Screening ◽  
Polymerase Chain

Abstract Background It is a challenging task to resume suspended surgical services following coronavirus disease 2019 (COVID-19) outbreaks. We aimed to investigate the results of the pre-admission screening for patients awaiting surgery during the COVID-19 pandemic. Methods This retrospective study enrolled consecutive 100 patients who underwent surgical procedures under general anesthesia at a single institution in May 2020. For 2 weeks prior to admission, patients were required to avoid nonessential outings and record symptoms and temperatures every day. On the day before admission, real-time polymerase chain reaction (PCR) and chest computed tomography (CT) were performed. Results Pre-admission PCRs were all negative, and no CT imaging suggested COVID-19 infection, combined with clinical information. As a result, all surgeries were performed as scheduled. No virus was detected from the extubated tracheal tubes in operating rooms. No patients developed COVID-19 infection postoperatively. No nosocomial infection was reported through the study period and for 1 month thereafter. Conclusions With 2-week avoidance of nonessential outings before admission for surgery, combined with reverse transcriptase PCR and chest CT shortly before admission, we successfully resumed elective surgeries, confirmed by PCR of extubated tracheal tube swabs, at a hospital that experienced a COVID-19 outbreak.

scholarly journals Chest CT versus RT-PCR for the Detection of COVID-19: Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Mohammad Karam ◽  
Sulaiman Althuwaikh ◽  
Mohammad Alazemi ◽  
Ahmad Abul ◽  
Amrit Hayre ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Systematic Review ◽  
Polymerase Chain Reaction ◽  
Meta Analysis ◽  
False Negative ◽  
Chest Ct ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Chest Computed Tomography ◽  
Polymerase Chain

AbstractPurposeTo compare the performance of chest computed tomography (CT) scan versus reverse transcription polymerase chain reaction (RT-PCR) in the initial diagnostic assessment of coronavirus disease 2019 (COVID-19) patients.MethodsA systematic review and meta-analysis were performed as per the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. A search of electronic information was conducted to identify all relevant studies comparing the diagnostic performance of chest CT scan versus RT-PCR in COVID-19 suspected cases. Sensitivity, specificity and accuracy were primary outcome measures. Secondary outcome measures included other test performance characteristics, discrepant findings between both investigations and main chest CT findings. Random effects modelling was used for the analyses.ResultsEight non-randomised retrospective studies enrolling 1910 patients were identified. Chest CT was more sensitive but less specific than RT-PCR. Accuracy was not statistically significantly different between chest CT and RT-PCR for the identification and exclusion of COVID-19 cases (Odds Ratio [OR] = 0.40, P = 0.15) in the context of hospitalised patients in a pandemic. Chest CT was shown to detect patients with false-negative RT-PCR results and true positives. Ground-glass opacities and consolidations were the most common chest CT manifestations.ConclusionsChest CT is not superior to RT-PCR for the initial detection of COVID-19 and has more false positives. It is likely to be useful in confirming COVID-19 in patients with a suspicious clinical presentation, but who have a false-negative SARS-CoV-2 RT-PCR test.Key Points‐Chest computed tomography (CT) is more sensitive but less specific in detecting and excluding coronavirus disease 2019 (COVID-19) when compared to reverse transcription polymerase chain reaction (RT-PCR).‐Accuracy of chest CT is not significantly different from RT-PCR for COVID-19 cases.‐Chest CT can detect false-negative and true-positive RT-PCR cases.

scholarly journals Accuracy of chest computed tomography and reverse transcription polymerase chain reaction in diagnosis of 2019 novel coronavirus disease; a systematic review and meta-analysis

2021 ◽  
Vol 7 (2) ◽  
pp. e36-e36
Author(s):  
Kamyar Shokraee ◽  
Hossein Mahdavi ◽  
Parsa Panahi ◽  
Farnoosh Seirafianpour ◽  
Amir Mohammad Jahromizadeh ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Systematic Review ◽  
Polymerase Chain Reaction ◽  
Reverse Transcription ◽  
Meta Analysis ◽  
Chest Ct ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Chest Computed Tomography ◽  
Polymerase Chain

Introduction: This study aims to measure the diagnostic accuracy of chest computed tomography (CT) and reverse transcription polymerase chain reaction assay (RT-PCR) in COVID-19 in a systematic review and meta-analysis. Methods: PubMed, Scopus, Embase, and Google Scholar, WHO, SSRN, and MedRxiv have been searched on March 26, 2020 for all the alternative names of the disease and virus. Risk of bias assessment was based on QUADAS-2. Data from English-language studies after January 12, 2019 were pooled to calculate necessary diagnostic values and underwent diagnostic test accuracy, random-effects, proportions, and subgroup meta-analysis. Results: Pooled from 27 included studies, the sensitivity of chest CT was calculated 96.6%, specificity 22.5%, diagnostic odds ratio (DOR) 8.2, positive likelihood ratio (PLR) 1.2 (95% CI: 1.1-1.4), and negative likelihood ratio (NLR) 0.15 (95% CI: 0.1-0.3). The sensitivity for initial RT-PCR was 79.7%, the specificity 100%, and NLR 0.18. Conclusion: Considering the results, in order to diagnose COVID-19 (coronavirus disease 2019), it is recommended to initially performing chest CT to rule out the uninfected people. In suspicious cases, we suggest RT-PCR to confirm the disease. Performing serial RT-PCR instead of the one-time test is highly recommended, to let the viral loads reach the diagnostic levels, especially in cases of high clinical suspicion.

scholarly journals CT scan chest findings in symptomatic COVID-19 patients: a reliable alternative for diagnosis

2020 ◽  
Vol 54 (4s) ◽  
pp. 97-99
Author(s):  
Benjamin D. Sarkodie ◽  
Yaw B. Mensah
Keyword(s):  
Computed Tomography ◽  
Ct Scan ◽  
Chest Ct ◽  
The Novel ◽  
Chain Reaction ◽  
High Diagnostic Accuracy ◽  
Diagnostic Potential ◽  
Polymerase Chain ◽  
Novel Coronavirus ◽  
Chest Ct Scan

Computed Tomography (CT) scan of the chest plays an important role in the diagnosis and management of Coronavirus disease 2019 (COVID-19), the disease caused by the novel coronavirus SARS-CoV-2. COVID-19 pneumoniashows typical CT Scan features which can aid diagnoses and therefore help in the early detection and isolation of infected patients. CT scanners are readily available in many parts of Ghana. It is able to show findings typical for COVID-19 infection of the chest, even in instances where Reverse Transcription Polymerase Chain Reaction (RTPCR) misses the diagnosis. Little is known about the diagnostic potential of chest CT scan and COVID-19 among physicians even though CT scan offers a high diagnostic accuracy.

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