scholarly journals Radiologic Criteria of Retropharyngeal Lymph Node Metastasis in Maxillary Sinus Cancer

2021 ◽  
Author(s):  
Yasuo Kosugi ◽  
Michimasa Suzuki ◽  
Mitsuhisa Fujimaki ◽  
Shinichi Ohba ◽  
Fumihiko Matsumoto ◽  
...  
Keyword(s):  
Maxillary Sinus ◽  
Characteristic Curve ◽  
Locally Advanced ◽  
Evaluation Criteria ◽  
Area Under The Curve ◽  
Complete Response ◽  
Axial Diameter ◽  
Before And After ◽  
Maxillary Sinus Cancer ◽  
Sinus Cancer

Abstract Objective: To determine the most appropriate radiologic criteria of metastatic retropharyngeal lymph nodes (RLNs) in patients with maxillary sinus cancer (MSC).Materials and Methods: We retrospectively evaluated 16 consecutive patients who underwent magnetic resonance imaging (MRI) before and after the treatment of locally advanced squamous cell carcinoma of the maxillary sinus. The minimal and maximal diameters of all RLNS were recorded. RLNs were classified as metastatic on the basis of the MRI follow-up (f/u). RLNs were considered non-metastatic if stable disease continued until the final MRI f/u and metastatic in cases with different evaluations (complete response, partial response, progressive disease) determined using Response Evaluation Criteria in Solid Tumours (RECIST) ver. 1.1. The receiver operating characteristic curve (ROC) and area under the curve (AUC) were used to assess the accuracy of various criteria in the diagnosis of metastatic RLNs. Results: Of the 34 RLNs in 16 cases observed on pretreatment MRI, 7 were classified as metastatic RLNs and 27 as non-metastatic RLNs. Using the radiologic criteria, metastatic RLNs tended to be diagnosed more accurately with the minimal axial diameter than with the maximal axial diameter (AUC; 0.97 vs. 0.73, p = 0.06). The most accurate size criterion of metastatic RLNs was a minimal axial diameter of 5 mm or larger, with an accuracy of 94.1% (32 of 34).Conclusions: The most appropriate radiologic criterion of metastatic RLNs in MSC is a minimal axial diameter of 5 mm or longer.

scholarly journals Radiologic criteria of retropharyngeal lymph node metastasis in maxillary sinus cancer

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Yasuo Kosugi ◽  
Michimasa Suzuki ◽  
Mitsuhisa Fujimaki ◽  
Shinichi Ohba ◽  
Fumihiko Matsumoto ◽  
...  
Keyword(s):  
Maxillary Sinus ◽  
Characteristic Curve ◽  
Locally Advanced ◽  
Evaluation Criteria ◽  
Area Under The Curve ◽  
Complete Response ◽  
Axial Diameter ◽  
Before And After ◽  
Maxillary Sinus Cancer ◽  
Sinus Cancer

Abstract Objective To determine the most appropriate radiologic criteria of metastatic retropharyngeal lymph nodes (RLNs) in patients with maxillary sinus cancer (MSC). Materials and methods We retrospectively evaluated 16 consecutive patients who underwent magnetic resonance imaging (MRI) before and after the treatment of locally advanced squamous cell carcinoma of the maxillary sinus. The minimal and maximal diameters of all RLNS were recorded. RLNs were classified as metastatic on the basis of the MRI follow-up (f/u). RLNs were considered non-metastatic if stable disease continued until the final MRI f/u and metastatic in cases with different evaluations (complete response, partial response, progressive disease) determined using Response Evaluation Criteria in Solid Tumours (RECIST) ver. 1.1. The receiver operating characteristic curve (ROC) and area under the curve (AUC) were used to assess the accuracy of various criteria in the diagnosis of metastatic RLNs. Results Of the 34 RLNs in 16 cases observed on pretreatment MRI, 7 were classified as metastatic RLNs and 27 as non-metastatic RLNs. Using the radiologic criteria, metastatic RLNs tended to be diagnosed more accurately with the minimal axial diameter than with the maximal axial diameter (AUC; 0.97 vs. 0.73, p = 0.06). The most accurate size criterion of metastatic RLNs was a minimal axial diameter of 5 mm or larger, with an accuracy of 94.1% (32 of 34). Conclusions The most appropriate radiologic criterion of metastatic RLNs in MSC is a minimal axial diameter of 5 mm or longer.

scholarly journals Invasion of the pterygoid plates: an indicator for regional lymph node failure in maxillary sinus cancer

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Yasuo Kosugi ◽  
Terufumi Kawamoto ◽  
Masaki Oshima ◽  
Mitsuhisa Fujimaki ◽  
Shinichi Ohba ◽  
...  
Keyword(s):  
Lymph Node ◽  
Oral Cavity ◽  
Maxillary Sinus ◽  
Regional Lymph Node ◽  
Locally Advanced ◽  
Intraarterial Chemotherapy ◽  
Node Failure ◽  
Long Term Treatment ◽  
Maxillary Sinus Cancer ◽  
Sinus Cancer

Abstract Background The aim of this study was to evaluate the long-term treatment results of combined superselective intraarterial chemotherapy and radiation therapy for advanced maxillary sinus cancer (MSC) and the incidence of regional lymph node failure, and to reveal the clinical and anatomical predictive factors for metastasis. Methods We retrospectively evaluated 55 consecutive patients with locally advanced squamous cell carcinoma of the maxillary sinus who were treated with external radiotherapy and superselective intraarterial chemotherapy. Elective nodal irradiation (ENI) was performed only in the clinical node-positive (cN+) cases and not in the clinical node-negative (cN0) cases. Results: Thirty-eight patients were cN0, and 17 were cN+ at diagnosis. Regional lymph node metastases occurred in 7 of 38 patients with cN0, and 2 of 17 with cN+ during the median follow-up period of 36 months. There were more cases of high-grade (3 or 4) late adverse events in the ENI group than in the non-ENI group (13% vs. 41%, respectively; p = 0.03). In cN0 cases without ENI, invasion of the pterygoid plates (57% vs. 90%; p < 0.01) and oral cavity (35% vs. 92%, with invasion vs without invasion, respectively; p = 0.02) was significantly correlated with a low 5-year regional recurrence-free rate. Conclusions Patients with MCS and invasion of the pterygoid plates and oral cavity can be considered appropriate candidates for ENI.

scholarly journals Invasion of Pterygoid Plates; an Indicator for Regional Lymph Node Failure in Maxillary Sinus Cancer

2020 ◽  
Author(s):  
Yasuo Kosugi ◽  
Terufumi Kawamoto ◽  
Masaki Oshima ◽  
Mitsuhisa Fujimaki ◽  
Shinichi Ohba ◽  
...  
Keyword(s):  
Lymph Node ◽  
Oral Cavity ◽  
Maxillary Sinus ◽  
Regional Lymph Node ◽  
Locally Advanced ◽  
Intraarterial Chemotherapy ◽  
Node Failure ◽  
Long Term Treatment ◽  
Maxillary Sinus Cancer ◽  
Sinus Cancer

Abstract Purpose: The aim of this study was to evaluate the long-term treatment results of combined superselective intraarterial chemotherapy and radiation therapy for advanced maxillary sinus cancer (MSC) and the incidence of regional lymph node failure, and to reveal the clinical and anatomical predictive factors for metastasis. Methods: We retrospectively evaluated 55 consecutive patients with locally advanced squamous cell carcinoma of the maxillary sinus who were treated with external radiotherapy and superselective intraarterial chemotherapy. Elective nodal irradiation (ENI) was performed only in the clinical node-positive (cN+) cases and not in the clinical node-negative (cN0) cases. Results: Thirty-eight patients were cN0, and 17 were cN+ at diagnosis. Regional lymph node metastases occurred in 7 of 38 patients with cN0, and 2 of 17 with cN+ during the median follow-up period of 36 months. There were more cases of high-grade (3 or 4) late adverse events in the ENI group than in the non-ENI group (13% vs. 41%, respectively; p = 0.03). In cN0 cases without ENI, invasion of the pterygoid plates (57% vs. 90%; p < 0.01) and oral cavity (35% vs. 92%; p = 0.02) was significantly correlated with a low 5-year regional recurrence-free rate. Conclusions: Patients with MCS and invasion of the pterygoid plates and oral cavity can be considered appropriate candidates for ENI.

scholarly journals Invasion of pterygoid plates; an indicator for regional lymph node failure in maxillary sinus cancer

2020 ◽  
Author(s):  
Yasuo Kosugi ◽  
Terufumi Kawamoto ◽  
Masaki Oshima ◽  
Mitsuhisa Fujimaki ◽  
Shinichi Ohba ◽  
...  
Keyword(s):  
Lymph Node ◽  
Oral Cavity ◽  
Maxillary Sinus ◽  
Regional Lymph Node ◽  
Locally Advanced ◽  
Intraarterial Chemotherapy ◽  
Node Failure ◽  
Long Term Treatment ◽  
Maxillary Sinus Cancer ◽  
Sinus Cancer

Abstract Purpose: The aim of this study was to evaluate the long-term treatment results of combined superselective intraarterial chemotherapy and radiation therapy for advanced maxillary sinus cancer (MSC) and the incidence of regional lymph node failure, and to reveal the clinical and anatomical predictive factors for metastasis. Methods: We retrospectively evaluated 55 consecutive patients with locally advanced squamous cell carcinoma of the maxillary sinus who were treated with external radiotherapy and superselective intraarterial chemotherapy. Elective nodal irradiation (ENI) was performed only in the clinical node-positive (cN+) cases and not in the clinical node-negative (cN0) cases. Results: Thirty-eight patients were cN0, and 17 were cN+ at diagnosis. Regional lymph node metastases occurred in 7 of 38 patients with cN0, and 2 of 17 with cN+ during the median follow-up period of 36 months. There were more cases of high-grade (3 or 4) late adverse events in the ENI group than in the non-ENI group (13% vs. 41%, respectively; p = 0.03). In cN0 cases without ENI, invasion of the pterygoid plates (57% vs. 90%; p < 0.01) and oral cavity (35% vs. 92%; p = 0.02) was significantly correlated with a low 5-year regional recurrence-free rate. Conclusions: Patients with MCS and invasion of the pterygoid plates and oral cavity can be considered appropriate candidates for ENI.

Effect of local extension sites on survival in locally advanced maxillary sinus cancer

Head & Neck ◽  
2013 ◽  
Vol 36 (11) ◽  
pp. 1567-1572 ◽  
Author(s):  
Satoshi Kano ◽  
Ryuichi Hayashi ◽  
Akihiro Homma ◽  
Kazuto Matsuura ◽  
Kengo Kato ◽  
...  
Keyword(s):  
Maxillary Sinus ◽  
Locally Advanced ◽  
Local Extension ◽  
Maxillary Sinus Cancer ◽  
Sinus Cancer
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