scholarly journals Retinal Nerve Fibre Layer and Ophthalmic Artery Blood Parameters in Pseudoexfoliation Syndrome and Pseudoexfoliative Glaucoma

Author(s):  
Hacı Koç ◽  
Faruk Kaya ◽  
Ümit İpeksoy

Abstract PurposeThis study investigates the relationship between ophthalmic artery blood flow parameters and retinal nerve fiber layer (RNFL) thickness in eyes with pseudoexfoliation. MethodsThree comparisons were made in this study. In the first, eyes without glaucoma with pseudoexfoliation in any of the eyes were compared with the control group. In the second, eyes with pseudoexfoliation and without glaucoma were compared with those with pseudoexfoliation and glaucoma. In the third, cases with glaucoma and pseudoexfoliation were compared with the control group. Ophthalmic artery colour Doppler imaging measurements were performed in all patients. Also, peripapillary RNFL analysis was performed. ResultsA statistically significant difference was found between the total RNFL measurements according to group (p = 0.012; p < 0.05). From the paired comparisons, the total RNFL measurements from the control group were higher than the group without glaucoma (p = 0.010). No statistically significant difference was found between the total RNFL measurements of the other groups (p > 0.05). In the pseudoexfoliative glaucoma (PXG) group, there was a statistically significant negative correlation between total RNLF and Peak systolic velocity (PSV) (r = -0.743; p < 0.01). There was also a statistically significant negative correlation between total RNLF and End diastolic velocity (EDV) (r = -0.691; p < 0.01). There was no significant relationship between total RNLF and resistive index (RI) measurements (p > 0.05). ConclusionPseudoexfoliation syndrome(PXS) caused a decrease in the PSV and EDV values of ophthalmic artery blood flow parameters. Again, PXS caused a decrease in total RNFL, RNFL S, RNFL I and RNFL T thickness values.

2015 ◽  
Vol 26 (2) ◽  
pp. 124-127 ◽  
Author(s):  
Tolga Kocaturk ◽  
Isil Isikligil ◽  
Burcin Uz ◽  
Volkan Dayanir ◽  
Yelda O. Dayanir

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Murat Dağdeviren ◽  
Tolga Akkan ◽  
Dilek Yapar ◽  
Serdar Karakaya ◽  
Tanyel Dağdeviren ◽  
...  

Abstract In our study, we aimed to evaluate changes in the neutrophil and lymphocyte series and investigate whether the neutrophil/lymphocyte ratio (NLR) is indicative of inflammations in patients with hyperthyroidism. A total of 161 patients were enrolled, 121 of which had hyperthyroidism (71 Graves’ Disease (GD) and 50 non-Graves hyperthyroidism (NGH) patients) and 40 of which were control group members. Retrospectively, patients’ neutrophil and lymphocyte counts were taken, and the NLR was calculated. While the number of neutrophils was significantly lower in the GD group (p = 0.003), there was no significant difference between the NGH and the control group. In the GD group, NLR values were significantly lower than the other two groups (median 1.39 for GD, median 1.84 for NGH and median 1.83 for the control group, p < 0.001). Only three patients in the GD group had neutropenia. There was also a significant negative correlation between free T3 and neutrophil count and NLR in hyperthyroid patients (r = -0.28, p = 0.001 and r = -0.34, p < 0.001, respectively). In our study, we found that NLR did not in crease in hyperthyroid patients and that this ratio decreased due to the decrease in neutrophil levels in GD. We thus concluded that NLR is not a suitable indicator of hyperthyroidism.


Ophthalmology ◽  
1997 ◽  
Vol 104 (4) ◽  
pp. 653-658 ◽  
Author(s):  
Luciano Quaranta ◽  
Alon Harris ◽  
Francesco Donato ◽  
Marta Cassamali ◽  
Francesco Semeraro ◽  
...  

2021 ◽  
Vol 74 (10) ◽  
pp. 2605-2609
Author(s):  
Tetyana M. Ternushchak ◽  
Marianna I. Tovt-Korshynska

The aim: To evaluate P-wave dispersion (PwD), as an independent predictor of atrial fibrillation, corrected QT interval dispersion (cQTD), the noninvasive marker of ventricular arrhythmia and sudden cardiac death, investigate the atrial electromechanical delay in patients with COPD and assess their relation with the severity of the disease. Materials and methods: We prospectively enrolled consecutive patients with newly diagnosed COPD (n = 53, age 41.2 ± 6.8 years), compared with an age-matched healthy control group (n = 51, age 40.9 ± 6.5 years). A standard 12-lead electrocardiogram of each patient was analyzed for PwD and сQTD. Atrial electromechanical delay was analyzed by echocardiographic tissue Doppler imaging. The difference between PAs-PAl, PAs-PAt, and PAl-PAt were defined as left intra-atrial, right intra-atrial, and interatrial electromechanical delays (EMD), respectively. Results: PwD was higher in COPD patients than in control subjects (39.47 ± 3.12 ms vs. 30.29 ± 3.17 ms, p < 0.05). In comparison between control group and COPD subgroups (mild, moderate and severe), there was a statistically significant difference among these free groups in terms of PwD. Subgroup analyses showed that this difference was mainly due to patients with severe COPD. Regarding cQTD, there was a statistically significant increase in COPD patients 57.92 ± 3.43 ms vs 41.03 ± 5.21 ms, p < 0.05 respectively. PAs, PAl and PAt durations, right intra-atrial and interatrial EMD were also significantly longer in COPD patients (p < 0.05). Furthermore, there were significant negative correlations between FEV1 and PwD (r = – 0.46, p < 0.05), right intra-atrial (r = – 0.39 ms, p < 0.05), interatrial EMD ( r = – 0.35 ms, p < 0.05) and cQTD (r = – 0.32, p < 0.05). Conclusions: Atrial conduction time, such as inter- and intra-atrial EMD intervals, PwD and cQTD were longer than in healthy controls and correlated with the severity of COPD. These parameters offer a non-invasive and cost-effective assessment method for detecting patients at high risk of arrhythmia. Nevertheless, further prospective investigations on this issue are required.


Author(s):  
Cesare Battaglia ◽  
Fulvia Mancini ◽  
Giorgia Regnani ◽  
Nicola Persico ◽  
Annibale Volpe ◽  
...  

2003 ◽  
Vol 18 (suppl 5) ◽  
pp. 18-22 ◽  
Author(s):  
Roberto Ferreira Meirelles Jr. ◽  
Reginaldo Ceneviva ◽  
José Liberato Ferreira Caboclo ◽  
Michael M. Eisenberg

PURPOSE: The pancreatic capillary blood flow (PCBF) was studied to determine its alterations during caerulein-induced pancreatitis in rats. METHODS: Twenty rats were divided in groups: control and caerulein. A laser-Doppler flowmeter to measure PCBF continuously was used. Blood pressure (BP) and heart rate (HR) were monitored. Serum biochemistry analyses were determined. Histopathological study was performed. RESULTS: The PCBF measured a mean of 109.08 ± 14.54% and 68.24 ± 10.47% in control group and caerulein group, respectively. Caerulein group had a mean decrease of 31.75 ± 16.79%. The serum amylase was 1323.70 ± 239.10U.I-1 and 2184.60 ± 700.46U.I-1 in control and caerulein groups, respectively. There was a significant difference in the PCBF (p<0.05) and serum amylase (p<0.05) when compared to control and caerulein groups. Although micro and microvacuolization were seen in 30% in caerulein group, no significant difference was seen between the groups. CONCLUSION: A decrease in the PCBF may be one of the leading events and it is present before histopathological tissue injury had been established in this model of acute pancreatitis.


2016 ◽  
Vol 73 (5) ◽  
pp. 429-434 ◽  
Author(s):  
Jelena Kostic ◽  
Milkica Nesic ◽  
Miodrag Stankovic ◽  
Olivera Zikic ◽  
Jasminka Markovic

Background/Aim. According to currently available data, there is no research dealing with evaluating empathy in adolescents with conduct disorders in our region. The aim of the research was to examine the differences in the severity of cognitive and affective empathy in adolescents with and with no conduct disorder, as well as to examine the relationship between cognitive and affective empathy and the level of externalization in adolescents with conduct disorder. Methods. This research was conducted on 171 adolescents, aged 15 to 18, using the Interpersonal Reactivity Index, Youth Self- Report and a Questionnaire constructed for the purpose of this research. Results. The results showed that adolescents with conduct disorder had significantly lower scores for Perspective Taking (t = 3.255, p = 0.001), Fantasy (t = 2.133, p = 0.034) and Empathic Concern (t = 2.479, p = 0.014) compared to the adolescents in the control group, while the values for Personal Distress (t = 1.818, p = 0.071) were higher compared to the control group, but the difference was not statistically significant. The study showed a statistically significant negative correlation between Perspective Taking and aggression (r = - 0.318, p = 0.003) and a negative correlation between Perspective Taking and the overall level of externalizing problems (r = -0.310, p = 0.004) in the group of adolescents with conduct disorder. Conclusion. This research contributes to better understanding of behavioral disorders in terms of individual factors, especially empathic reactivity. Preventive work with young people who have behavioral problems associated with empathy deficit disorder proved to be an important tool in preventing the development, or at least relieving the symptoms, of this ever more common disorder.


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