scholarly journals Reversal Flow in the Left Anterior Descending Artery After Internal Thoracic Artery Grafting

Author(s):  
Hiroyuki Nakajima ◽  
Akitoshi Takazawa ◽  
Yoshitsugu Nakamura ◽  
Hatsue Ishibashi-Ueda ◽  
Akihiro Yoshitake ◽  
...  

Abstract Background: The flow capacity of the in situ internal thoracic artery (ITA) is not necessarily sufficient and can be a cause of hypoperfusion syndrome. We present a catastrophic case of in situ ITA grafting for an isolated left main trunk obstruction 13 years after modified Bentall operation. Case presentation: A 33-year-old woman had previously undergone a modified Bentall operation. Coronary angiography showed a critical stenosis in the left coronary artery. The patient underwent emergent off-pump CABG with the left internal thoracic artery (ITA) to the left anterior descending artery (LAD). On the seventh day, the patient had severe dyspnoea and hypotension. Catheter angiography showed that the ITA was patent, but blood flow from the in situ ITA was delayed, and reversal flow from the apex to the proximal LAD was found. The patient underwent implantation of a left ventricular assist device. Conclusions: In conclusion, concomitant aortocoronary bypass to the circumflex branch will minimise the risk of hypoperfusion, especially for a young patient without atherosclerotic disease.

2021 ◽  
pp. 021849232098149
Author(s):  
Aya Saito ◽  
Hiraku Kumamaru ◽  
Noboru Motomura ◽  
Hiroaki Miyata ◽  
Shinichi Takamoto

Background Clinical outcomes (as national clinical data) of isolated coronary artery bypass grafting have been successively reported, based on data registered in the Japan Cardiovascular Surgery Database, since 2013. In this study, we analysed the clinical results of isolated coronary artery bypass from 2017 to 2018 as a biannual report. Methods Data from the Japan Cardiovascular Surgery Database on isolated coronary artery bypass performed in 2017 and 2018 were reviewed for preoperative characteristics, postoperative outcomes, and choice of graft material for the left anterior descending artery. Results Isolated off-pump coronary artery bypass was performed in 54.6% ( n = 14,684) of all coronary artery bypass cases ( n = 26,913), and graft material for the left anterior descending artery was the left internal thoracic artery in 76.4% of cases and the right internal thoracic artery in 19.0% of cases. Operative mortality was 1.5% in elective cases (on-pump coronary artery bypass 1.9% and off-pump 1.2%, p < 0.001), 7.4% in emergency cases (on-pump 10.2% and off-pump 4.3%, p < 0.001), and 2.5% overall. Postoperative morbidity was generally lower in off-pump coronary artery bypass. The severity of surgery with expected mortality, evaluated using JapanSCORE II, is increasing every year. Conclusions Our findings suggest that short-term operative results for isolated coronary artery bypass are stable, and operative candidates are shifting to higher-risk patients.


2015 ◽  
Vol 60 (2) ◽  
pp. 795-800 ◽  
Author(s):  
M. Kopernik ◽  
A. Milenin ◽  
S. Kąc

Abstract The Polish left ventricular assist device (LVAD – RELIGA_EXT) will be made of thermoplastic polycarbonate-urethane (Bionate II) with deposited athrombogenic nano-coatings: gold (Au) and titanium nitride (TiN). Referring to the physical model, the two-scale model of LVAD developed in the previous works in the authors’ finite element code is composed of a macro-model of blood chamber and a micro-model of wall: TiN, Au and Bionate II. The numerical analysis of stress and strain states confirmed the possibility of fracture based on localization of zones of the biggest values of triaxiality factor. The introduction of Au interlayer between TiN and polymer improved the toughness of the connection, and increased the compressive residual stress in the coating what resulted in reduction of stress and strain close to the boundary between substrate and coating. However, the proper design of multilayer wall of the medical device requires the introduction of the real stress and strain states in the deposited coatings. The characteristics of TiN nano-coating such as residual stress, material model and fracture model were determined in the previously completed studies such as experimental and numercial nanoindentation tests, profilometry studies and in situ SEM’s micro-tension tests. The experimental in situ SEM’s micro-shear test was performed in the present paper and the corresponding numerical model of the test was also developed, and then, interpreted. The critical strains taken from experiment and considered as the effective strains in the model of test are the values which are the function of triaxiality factors for the tested samples. The developed in the authors’ FE code model of multilayer wall of VAD enriched with critical strain determined in the present paper enables prediction of fracture.


Author(s):  
Shinji Ogawa ◽  
Tomohiro Tsunekawa ◽  
Soh Hosoba ◽  
Yoshihiro Goto ◽  
Takayoshi Kato ◽  
...  

Abstract OBJECTIVES To compare different configurations of the bilateral internal thoracic arteries for the left coronary system and examine early and late outcomes, including mid-term graft patency. METHODS We reviewed 877 patients who underwent primary isolated coronary artery bypass grafting using in situ bilateral internal thoracic arteries [in situ right internal thoracic artery (RITA)-to-left anterior descending artery (LAD) grafting, n = 683; in situ left internal thoracic artery (LITA)-to-LAD grafting, n = 194]. We compared mid-term patency between the grafts. Propensity score matching was performed to investigate early and long-term outcomes. RESULTS The 2-year patency rate for RITA-to-LAD and LITA-to-LAD grafts were similar. Multivariate analysis revealed that RITA-to-non-LAD anastomosis (P = 0.029), postoperative length of stay (P = 0.003) and chronic obstructive pulmonary disease (P = 0.005) were associated with graft failure. After statistical adjustment, 176 propensity-matched pairs were available for comparison. RITA-to-LAD grafting enabled a more distal anastomosis. Kaplan–Meier analysis revealed that the incidences of death, repeat revascularization and myocardial infarction were significantly higher in the LITA-to-LAD group among both the unmatched and matched samples (P = 0.045 and 0.029, respectively). CONCLUSIONS The mid-term patency and outcomes of RITA-to-LAD grafting are good and reduces future cardiac event, in contrast to LITA-to-LAD grafting.


ASAIO Journal ◽  
2017 ◽  
Vol 63 (1) ◽  
pp. 68-72 ◽  
Author(s):  
Igor D. Gregoric ◽  
Rajko Radovancevic ◽  
Mehmet H. Akay ◽  
Mateja K. Jezovnik ◽  
Sriram Nathan ◽  
...  

2010 ◽  
Vol 34 (12) ◽  
pp. 1156-1158 ◽  
Author(s):  
Kyriakos Anastasiadis ◽  
Stephen Westaby ◽  
Polychronis Antonitsis ◽  
Helena Argiriadou ◽  
Georgios Karapanagiotidis ◽  
...  

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