scholarly journals TMIGD1, a Putative Tumor Suppressor, Induces G2-M Cell Cycle Checkpoint Arrest in Colon Cancer Cells

2020 ◽  
Author(s):  
Kyle De La Cena ◽  
Rachel Xi-Yeen Ho ◽  
Razie Amraei ◽  
Nick Woolf ◽  
Joseph Y. Tashjian ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Colon Cancer ◽  
Tumor Suppressor ◽  
Cancer Cells ◽  
Cell Cycle Checkpoint ◽  
Colon Cancer Cells ◽  
M Cell ◽  
Putative Tumor Suppressor ◽  
Cycle Checkpoint

scholarly journals Transmembrane and Immunoglobulin Domain Containing 1, a Putative Tumor Suppressor, Induces G2/M Cell Cycle Checkpoint Arrest in Colon Cancer Cells

2021 ◽  
Vol 191 (1) ◽  
pp. 157-167
Author(s):  
Kyle O.C. De La Cena ◽  
Rachel X.-Y. Ho ◽  
Razie Amraei ◽  
Nick Woolf ◽  
Joseph Y. Tashjian ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Colon Cancer ◽  
Tumor Suppressor ◽  
Cancer Cells ◽  
Cell Cycle Checkpoint ◽  
Colon Cancer Cells ◽  
M Cell ◽  
Putative Tumor Suppressor ◽  
Cycle Checkpoint ◽  
Immunoglobulin Domain

scholarly journals Retraction Note to: Quinoxaline 1,4-dioxides induce G2/M cell cycle arrest and apoptosis in human colon cancer cells

2018 ◽  
Vol 81 (3) ◽  
pp. 627-627 ◽  
Author(s):  
Hala U. Gali-Muhtasib ◽  
Mona Diab-Assaf ◽  
Makhluf J. Haddadin
Keyword(s):  
Cell Cycle ◽  
Colon Cancer ◽  
Cell Cycle Arrest ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
M Cell ◽  
Human Colon Cancer ◽  
Cycle Arrest ◽  
Human Colon Cancer Cells

scholarly journals HY-1 induces G2 / M cell cycle arrest in human colon cancer cells through the ATR-Chk1-Cdc25C and Weel pathways

2013 ◽  
Vol 104 (8) ◽  
pp. 1062-1066 ◽  
Author(s):  
Yu Zhao ◽  
Zhonghua Wu ◽  
Yuting Zhang ◽  
Li Zhu
Keyword(s):  
Cell Cycle ◽  
Colon Cancer ◽  
Cell Cycle Arrest ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
M Cell ◽  
Human Colon Cancer ◽  
Cycle Arrest ◽  
Human Colon Cancer Cells

scholarly journals A methoxyflavanone derivative, 2′,3′,4′-trimethoxy-5,6-naphthoflavanone, inhibits proliferation of HCT116 human colon cancer cells by inducing G2/M cell cycle arrest and apoptosis

2016 ◽  
Vol 59 (2) ◽  
pp. 249-253 ◽  
Author(s):  
Kyungho Lee ◽  
Da Hyun Lee ◽  
You Jung Jung ◽  
Soon Young Shin ◽  
Dongsoo Koh ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Colon Cancer ◽  
Cell Cycle Arrest ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
M Cell ◽  
Human Colon Cancer ◽  
Cycle Arrest ◽  
Human Colon Cancer Cells

scholarly journals HRT, Herbal Formula, Induces G2/M Cell Cycle Arrest and Apoptosis via Suppressing Akt Signaling Pathway in Human Colon Cancer Cells

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Nam-Hui Yim ◽  
Won-Kyung Cho ◽  
Ju Hye Lee ◽  
Young Pil Jung ◽  
Hye Jin Yang ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Colon Cancer ◽  
Cell Cycle Arrest ◽  
Cancer Cells ◽  
Signaling Pathway ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
M Cell ◽  
Human Colon Cancer ◽  
Cycle Arrest

We have demonstrated the anticancer effect of HRT in HCT116, human colon carcinoma cells. HRT inhibited cancer cell growth by causing cell cycle arrest at G2/M and inducing apoptosis as evidenced by DNA fragmentation assay. We found that HRT induces the activation of caspase-3, -8, and -9, whereas it reduces the level of Bcl-2 protein and results in the cleavage of PARP. Further, HRT decreased the level of phosphorylation of Akt and its downstream signals such as mTOR and GSK-3β. These results indicate that HRT stimulates the apoptotic signaling pathway and represses the survival and proliferation of colon cancer cells via inhibiting Akt activity. Hence, our results suggest that HRT has a potential to be developed as a therapeutic agent against colon cancer cells.

A new synthetic 2′-hydroxy-2,4,6-trimethoxy-5′,6′-naphthochalcone induces G2/M cell cycle arrest and apoptosis by disrupting the microtubular network of human colon cancer cells

2014 ◽  
Vol 354 (2) ◽  
pp. 348-354 ◽  
Author(s):  
Jong Min Lee ◽  
Mi So Lee ◽  
Dongsoo Koh ◽  
Young Han Lee ◽  
Yoongho Lim ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Colon Cancer ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
M Cell ◽  
Human Colon Cancer ◽  
Cycle Arrest ◽  
Microtubular Network ◽  
Human Colon Cancer Cells

Abstract 2107: Tetra-arsenic hexoxide induces G2/M cell cycle arrest, apoptosis, and autophagy via p38 MAPK- and AKT-mediated pathways in SW620 human colon cancer cells

2017 ◽  
Author(s):  
Won Sup Lee ◽  
Jeong Won Yun ◽  
Min Jeong Kim ◽  
Arulkumar Nagappan ◽  
Jing Nan Lu ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Colon Cancer ◽  
Cell Cycle Arrest ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
M Cell ◽  
Human Colon Cancer ◽  
Cycle Arrest ◽  
Human Colon Cancer Cells
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