Fixed Dosing of Tocilizumab in ICU Admitted COVID-19 Patients Is a Superior Choice Compared to Bodyweight Based Dosing; An Observational Population Pharmacokinetic and Pharmacodynamic Study

SSRN Electronic Journal ◽

10.2139/ssrn.3835128 ◽

2021 ◽

Author(s):

Dirk Jan Moes ◽

David van Westerloo ◽

Sandra Arend ◽

Jesse Swen ◽

Annick De Vries ◽

...

Keyword(s):

Population Pharmacokinetic ◽

Pharmacodynamic Study

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Downregulation of ABCB1 gene in patients with total hip or knee arthroplasty influences pharmacokinetics of rivaroxaban: a population pharmacokinetic-pharmacodynamic study

European Journal of Clinical Pharmacology ◽

10.1007/s00228-019-02639-8 ◽

2019 ◽

Vol 75 (6) ◽

pp. 817-824 ◽

Author(s):

Jurij Zdovc ◽

Maja Petre ◽

Mitja Pišlar ◽

Katja Repnik ◽

Aleš Mrhar ◽

...

Keyword(s):

Knee Arthroplasty ◽

Population Pharmacokinetic ◽

Total Hip ◽

Pharmacodynamic Study

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Continuous infusion of physostigmine in patients with perioperative septic shock: A pharmacokinetic/pharmacodynamic study with population pharmacokinetic modeling

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2019.109318 ◽

2019 ◽

Vol 118 ◽

pp. 109318

Author(s):

Nadine Pinder ◽

Johannes B. Zimmermann ◽

Silke Gastine ◽

Gudrun Würthwein ◽

Georg Hempel ◽

...

Keyword(s):

Septic Shock ◽

Continuous Infusion ◽

Pharmacokinetic Modeling ◽

Population Pharmacokinetic ◽

Population Pharmacokinetic Modeling ◽

Pharmacodynamic Study

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Safety and pharmacology of paclitaxel in patients with impaired liver function: a population pharmacokinetic–pharmacodynamic study

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.2007.02956.x ◽

2007 ◽

Vol 64 (5) ◽

pp. 622-633 ◽

Author(s):

M. Joerger ◽

A. D. R. Huitema ◽

M. T. Huizing ◽

P. H. B. Willemse ◽

A. de Graeff ◽

...

Keyword(s):

Liver Function ◽

Population Pharmacokinetic ◽

Impaired Liver Function ◽

Impaired Liver ◽

Pharmacodynamic Study

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Isepamicin in intensive care unit patients with nosocomial pneumonia: population pharmacokinetic–pharmacodynamic study

Journal of Antimicrobial Chemotherapy ◽

10.1093/jac/44.1.99 ◽

1999 ◽

Vol 44 (1) ◽

pp. 99-108 ◽

Author(s):

M. Tod ◽

C. Minozzi ◽

G. Beaucaire ◽

D. Ponsonnet ◽

J. Cougnard ◽

...

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Nosocomial Pneumonia ◽

Population Pharmacokinetic ◽

Pharmacodynamic Study

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An optimized ibuprofen dosing scheme for preterm neonates with patent ductus arteriosus, based on a population pharmacokinetic and pharmacodynamic study

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.2008.03118.x ◽

2008 ◽

Vol 65 (5) ◽

pp. 629-636 ◽

Author(s):

Déborah Hirt ◽

Bart Van Overmeire ◽

Jean-Marc Treluyer ◽

Jean-Paul Langhendries ◽

Arnaud Marguglio ◽

...

Keyword(s):

Patent Ductus Arteriosus ◽

Ductus Arteriosus ◽

Preterm Neonates ◽

Population Pharmacokinetic ◽

Pharmacodynamic Study ◽

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Reporting a Population Pharmacokinetic–Pharmacodynamic Study: A Journal’s Perspective

Clinical Pharmacokinetics ◽

10.1007/s40262-013-0114-1 ◽

2013 ◽

Vol 53 (2) ◽

pp. 111-122 ◽

Author(s):

Kris M. Jamsen ◽

Sarah C. McLeay ◽

Michael A. Barras ◽

Bruce Green

Keyword(s):

Population Pharmacokinetic ◽

Pharmacodynamic Study

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Towards Fixed Dosing of Tocilizumab in ICU-Admitted COVID-19 Patients: Results of an Observational Population Pharmacokinetic and Descriptive Pharmacodynamic Study

Clinical Pharmacokinetics ◽

10.1007/s40262-021-01074-2 ◽

2021 ◽

Author(s):

Dirk Jan A. R. Moes ◽

David J. van Westerloo ◽

Sandra M. Arend ◽

Jesse J. Swen ◽

Annick de Vries ◽

...

Keyword(s):

Population Pharmacokinetic ◽

Pharmacodynamic Study

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A Population Pharmacokinetic and Pharmacodynamic Study of a Peripheral κ-Opioid Receptor Agonist CR665 and Oxycodone

Clinical Pharmacokinetics ◽

10.1007/s40262-012-0023-8 ◽

2012 ◽

Vol 52 (2) ◽

pp. 125-137 ◽

Author(s):

Anne E. Olesen ◽

Kim Kristensen ◽

Camilla Staahl ◽

Sherron Kell ◽

Gilbert Y. Wong ◽

...

Keyword(s):

Opioid Receptor ◽

Receptor Agonist ◽

Population Pharmacokinetic ◽

Opioid Receptor Agonist ◽

Pharmacodynamic Study

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Visceral leishmaniasis relapse hazard is linked to reduced miltefosine exposure in patients from Eastern Africa: a population pharmacokinetic/pharmacodynamic study

Journal of Antimicrobial Chemotherapy ◽

10.1093/jac/dkx283 ◽

2017 ◽

Vol 72 (11) ◽

pp. 3131-3140 ◽

Author(s):

Thomas P C Dorlo ◽

Anke E Kip ◽

Brima M Younis ◽

Sally J Ellis ◽

Fabiana Alves ◽

...

Keyword(s):

Visceral Leishmaniasis ◽

Eastern Africa ◽

Population Pharmacokinetic ◽

Pharmacodynamic Study

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Population Pharmacokinetic Analysis of Recombinant Fusion Protein Linking Coagulation Factor IX with Recombinant Albumin (rIX-FP) in Adult and Pediatric Patients with Severe Hemophilia B

10.1055/s-0039-1680223 ◽

2019 ◽

Author(s):

Y. Zhang ◽

W. McKeand ◽

T. Yuraszeck ◽

W. Seifert ◽

A. Feussner ◽

...

Keyword(s):

Fusion Protein ◽

Pediatric Patients ◽

Coagulation Factor ◽

Population Pharmacokinetic Analysis ◽

Factor Ix ◽

Hemophilia B ◽

Pharmacokinetic Analysis ◽

Population Pharmacokinetic ◽

Severe Hemophilia ◽

Coagulation Factor Ix

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