3F1022 Single amino acid substitution in the transmembrane domain of metabotropic glutamate receptor changes an agonist into an inverse agonist(Membrane Proteins,Oral Presentation)

Transmembrane Domain ◽

Single Amino Acid ◽

Metabotropic Glutamate

Glutamate Acts as a Partial Inverse Agonist to Metabotropic Glutamate Receptor with a Single Amino Acid Mutation in the Transmembrane Domain

10.1074/jbc.m112.437780 ◽

2013 ◽

Vol 288 (14) ◽

pp. 9593-9601 ◽

Cited By ~ 11

Author(s):

Masataka Yanagawa ◽

Takahiro Yamashita ◽

Yoshinori Shichida

Keyword(s):

Amino Acid ◽

Glutamate Receptor ◽

Transmembrane Domain ◽

Inverse Agonist ◽

Single Amino Acid ◽

Amino Acid Mutation ◽

Metabotropic Glutamate ◽

Partial Inverse ◽

Single Amino Acid Mutation

2P341 Amino acid interactions in the transmembrane domain responsible for the activation process of metabotropic glutamate receptor(Photobiology-vision and photoreception,Oral Presentations)

Seibutsu Butsuri ◽

10.2142/biophys.47.s198_2 ◽

2007 ◽

Vol 47 (supplement) ◽

pp. S198

Author(s):

Masataka Yanagawa ◽

Takahiro Yamashita ◽

Yoshinori Shichida

Keyword(s):

Amino Acid ◽

Glutamate Receptor ◽

Transmembrane Domain ◽

Activation Process ◽

Metabotropic Glutamate ◽

Oral Presentations

A single amino acid substitution within the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein renders simian–human immunodeficiency virus (SHIVKU-1bMC33) susceptible to rimantadine

Virology ◽

10.1016/j.virol.2005.12.025 ◽

2006 ◽

Vol 348 (2) ◽

pp. 449-461 ◽

Cited By ~ 27

Author(s):

David R. Hout ◽

Lisa M. Gomez ◽

Erik Pacyniak ◽

Jean-Marie Miller ◽

M. Sarah Hill ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Amino Acid ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Amino Acid Substitution ◽

Transmembrane Domain ◽

Single Amino Acid ◽

Immunodeficiency Virus

Activation of insulin receptor signaling by a single amino acid substitution in the transmembrane domain.

10.1016/s0021-9258(18)42290-9 ◽

1992 ◽

Vol 267 (18) ◽

pp. 12416-12419

Author(s):

N Longo ◽

R.C. Shuster ◽

L.D. Griffin ◽

S.D. Langley ◽

L.J. Elsas

Keyword(s):

Amino Acid ◽

Insulin Receptor ◽

Amino Acid Substitution ◽

Transmembrane Domain ◽

Single Amino Acid ◽

Receptor Signaling ◽

Insulin Receptor Signaling

Faculty Opinions recommendation of Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718499023.793498248 ◽

2014 ◽

Author(s):

Roland Seifert

Keyword(s):

Glutamate Receptor ◽

Transmembrane Domain ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate ◽

Class C

Faculty Opinions recommendation of A single amino acid substitution in the movement protein enables the mechanical transmission of a geminivirus.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.737608820.793572784 ◽

2020 ◽

Author(s):

Vitaly Citovsky

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Movement Protein ◽

Single Amino Acid ◽

Mechanical Transmission

A large compressibility change of protein induced by a single amino acid substitution

Protein Science ◽

10.1002/pro.5560050319 ◽

1996 ◽

Vol 5 (3) ◽

pp. 542-545 ◽

Cited By ~ 18

Author(s):

Kunihiko Gekko ◽

Youjiro Tamura ◽

Eiji Ohmae ◽

Hideyuki Hayashi ◽

Hiroyuki Kagamiyama ◽

...

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Single Amino Acid

A single amino acid substitution flanking the fourth calcium binding domain of alpha IIb prevents maturation of the alpha IIb beta 3 integrin complex.

10.1016/s0021-9258(17)41800-x ◽

1994 ◽

Vol 269 (6) ◽

pp. 4450-4457

Author(s):

D.A. Wilcox ◽

J.L. Wautier ◽

D. Pidard ◽

P.J. Newman

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Calcium Binding ◽

Binding Domain ◽

Single Amino Acid ◽

Calcium Binding Domain

A single amino acid substitution in the A subunit of Escherichia coli enterotoxin results in a loss of its toxic activity.

10.1016/s0021-9258(18)45736-5 ◽

1990 ◽

Vol 265 (36) ◽

pp. 22520-22525

Author(s):

T Tsuji ◽

T Inoue ◽

A Miyama ◽

K Okamoto ◽

T Honda ◽

...

Keyword(s):

Escherichia Coli ◽

Amino Acid ◽

Amino Acid Substitution ◽

Single Amino Acid ◽

Toxic Activity ◽

A Subunit

Alteration of Ca2+ permeability and sensitivity to Mg2+ and channel blockers by a single amino acid substitution in the N-methyl-D-aspartate receptor.

10.1016/s0021-9258(18)54166-1 ◽

1993 ◽

Vol 268 (1) ◽

pp. 410-415

Author(s):

K. Sakurada ◽

M. Masu ◽

S. Nakanishi

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Single Amino Acid ◽

Channel Blockers ◽

Aspartate Receptor