Activation of insulin receptor signaling by a single amino acid substitution in the transmembrane domain.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42290-9 ◽

1992 ◽

Vol 267 (18) ◽

pp. 12416-12419

Author(s):

N Longo ◽

R.C. Shuster ◽

L.D. Griffin ◽

S.D. Langley ◽

L.J. Elsas

Keyword(s):

Insulin Receptor ◽

Amino Acid Substitution ◽

Transmembrane Domain ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Receptor Signaling ◽

Insulin Receptor Signaling

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3F1022 Single amino acid substitution in the transmembrane domain of metabotropic glutamate receptor changes an agonist into an inverse agonist(Membrane Proteins,Oral Presentation)

Seibutsu Butsuri ◽

10.2142/biophys.52.s66_5 ◽

2012 ◽

Vol 52 (supplement) ◽

pp. S66

Author(s):

Masataka Yanagawa ◽

Takahiro Yamashita ◽

Yoshinori Shichida

Keyword(s):

Membrane Proteins ◽

Glutamate Receptor ◽

Oral Presentation ◽

Amino Acid Substitution ◽

Metabotropic Glutamate Receptor ◽

Transmembrane Domain ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Metabotropic Glutamate

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A Conservative, Single-Amino Acid Substitution in the Second Cytoplasmic Domain of the Human Serotonin2C Receptor Alters Both Ligand-Dependent and -Independent Receptor Signaling

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.107.131524 ◽

2007 ◽

Vol 324 (3) ◽

pp. 1084-1092 ◽

Author(s):

Kelly A. Berg ◽

John Dunlop ◽

Teresa Sanchez ◽

Michelle Silva ◽

William P. Clarke

Keyword(s):

Amino Acid Substitution ◽

Cytoplasmic Domain ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Receptor Signaling

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Faculty Opinions recommendation of A conservative, single-amino acid substitution in the second cytoplasmic domain of the human Serotonin2C receptor alters both ligand-dependent and -independent receptor signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1115660.572679 ◽

2008 ◽

Author(s):

Kathryn Cunningham

Keyword(s):

Amino Acid Substitution ◽

Cytoplasmic Domain ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Receptor Signaling

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A single amino acid substitution within the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein renders simian–human immunodeficiency virus (SHIVKU-1bMC33) susceptible to rimantadine

Virology ◽

10.1016/j.virol.2005.12.025 ◽

2006 ◽

Vol 348 (2) ◽

pp. 449-461 ◽

Author(s):

David R. Hout ◽

Lisa M. Gomez ◽

Erik Pacyniak ◽

Jean-Marie Miller ◽

M. Sarah Hill ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Amino Acid Substitution ◽

Transmembrane Domain ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Immunodeficiency Virus

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Faculty Opinions recommendation of A single amino acid substitution in the movement protein enables the mechanical transmission of a geminivirus.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.737608820.793572784 ◽

2020 ◽

Author(s):

Vitaly Citovsky

Keyword(s):

Amino Acid Substitution ◽

Movement Protein ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Mechanical Transmission

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A large compressibility change of protein induced by a single amino acid substitution

Protein Science ◽

10.1002/pro.5560050319 ◽

1996 ◽

Vol 5 (3) ◽

pp. 542-545 ◽

Author(s):

Kunihiko Gekko ◽

Youjiro Tamura ◽

Eiji Ohmae ◽

Hideyuki Hayashi ◽

Hiroyuki Kagamiyama ◽

...

Keyword(s):

Amino Acid Substitution ◽

Single Amino Acid Substitution ◽

Single Amino Acid

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A single amino acid substitution flanking the fourth calcium binding domain of alpha IIb prevents maturation of the alpha IIb beta 3 integrin complex.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)41800-x ◽

1994 ◽

Vol 269 (6) ◽

pp. 4450-4457

Author(s):

D.A. Wilcox ◽

J.L. Wautier ◽

D. Pidard ◽

P.J. Newman

Keyword(s):

Amino Acid Substitution ◽

Calcium Binding ◽

Binding Domain ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Calcium Binding Domain

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A single amino acid substitution in the A subunit of Escherichia coli enterotoxin results in a loss of its toxic activity.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)45736-5 ◽

1990 ◽

Vol 265 (36) ◽

pp. 22520-22525

Author(s):

T Tsuji ◽

T Inoue ◽

A Miyama ◽

K Okamoto ◽

T Honda ◽

...

Keyword(s):

Escherichia Coli ◽

Amino Acid Substitution ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Toxic Activity ◽

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Alteration of Ca2+ permeability and sensitivity to Mg2+ and channel blockers by a single amino acid substitution in the N-methyl-D-aspartate receptor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54166-1 ◽

1993 ◽

Vol 268 (1) ◽

pp. 410-415

Author(s):

K. Sakurada ◽

M. Masu ◽

S. Nakanishi

Keyword(s):

Amino Acid Substitution ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Channel Blockers ◽

Aspartate Receptor

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A single amino acid substitution in the R2R3 conserved domain of the BrPAP1a transcription factor impairs anthocyanin production in turnip (Brassica rapa subsp. rapa)

Plant Physiology and Biochemistry ◽

10.1016/j.plaphy.2021.02.011 ◽

2021 ◽

Vol 162 ◽

pp. 124-136

Author(s):

Jianfei Yang ◽

Hyon Dok Song ◽

Yunzhu Chen ◽

Bowei Chen ◽

Minjun Kim ◽

...

Keyword(s):

Transcription Factor ◽

Brassica Rapa ◽

Amino Acid Substitution ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Conserved Domain ◽

Anthocyanin Production

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