Brucella endocarditis complicated by acute glomerulonephritis

2001 ◽  
Vol 56 (6) ◽  
pp. 399-400 ◽  
Author(s):  
Diana SHARIVKER ◽  
Alicia VAZAN ◽  
Jacob VARKEL
2021 ◽  
Vol 14 (1) ◽  
pp. e236695 ◽  
Author(s):  
Rasmi Ranjan Sahoo ◽  
Sourav Pradhan ◽  
Akhil Pawan Goel ◽  
Anupam Wakhlu

Staphylococcus-associated glomerulonephritis (SAGN) occurs as a complication of staphylococcal infection elsewhere in the body. Dermatomyositis (DM) can be associated with glomerulonephritis due to the disease per se. We report a case of a 40-year-old male patient with DM who presented with acute kidney injury, and was initially pulsed with methylprednisolone for 3 days, followed by dexamethasone equivalent to 1 mg/kg/day prednisolone. He was subsequently found to have SAGN on kidney biopsy along with staphylococcus bacteraemia and left knee septic arthritis. With proof of definitive infection, intravenous immunoglobulin 2 g/kg over 2 days was given and steroids were reduced. He was treated with intravenous vancomycin. With treatment, the general condition of the patient improved. On day 38, he developed infective endocarditis and died of congestive heart failure subsequently. Undiagnosed staphylococcal sepsis complicating a rheumatological disease course can lead to complications like SAGN, infective endocarditis and contribute to increased morbidity and mortality, as is exemplified by our case.


Author(s):  
Emre Leventoğlu ◽  
Bahar Büyükkaragöz ◽  
Zühre Kaya ◽  
Kibriya Fidan ◽  
Oğuz Söylemezoğlu ◽  
...  

Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 962-967
Author(s):  
Nami Sawada ◽  
Tamaki Morohashi ◽  
Tomokazu Mutoh ◽  
Tsukasa Kuwana ◽  
Junko Yamaguchi ◽  
...  

AbstractMoraxella lacunata (M. lacunata) is a Gram-negative bacterium, which rarely causes serious infection. This is a rare case report of acute glomerulonephritis diagnosed by pathological findings in a child accompanied by M. lacunata infection. The patient showed hematuria, proteinuria and hyperkalemia requiring emergency hemodialysis. After hospitalization, M. lacunata bacteremia became apparent. Pathological findings showed an increase in glomerulus inflammatory cells and glomerular C3 deposition was observed in the renal tissue biopsy. Final diagnosis was endocapillary proliferative glomerulonephritis. Clinical reports of M. lacunata infection requiring emergency hemodialysis in children are rare. Previous reports have suggested that lowered immune competency with chronic kidney disease may be a risk factor associated with serious invasive cases of M. lacunata infection. However, detailed clinical laboratory data and pathological findings have not been identified in previous case reports. Our case directly indicated complement activity and acute glomerulonephritis with M. lacunata infection. Although there are various causes for acute glomerulonephritis, infection-related glomerulonephritis (IRGN) is an important concept. M. lacunata infection might have a potential risk for IRGN with dysregulation of complement activity leading to serious and invasive clinical conditions than previously considered.


2021 ◽  
Vol 6 (4) ◽  
pp. S55
Author(s):  
S. Chargui ◽  
Z. Hamdi ◽  
A. Harzallah ◽  
M. Mbarek ◽  
R. Houili ◽  
...  

2013 ◽  
Vol 23 (6) ◽  
pp. 1221-1225
Author(s):  
Yuichiro Kitai ◽  
Kosaku Murakami ◽  
Hajime Yoshifuji ◽  
Naoichiro Yukawa ◽  
Daisuke Kawabata ◽  
...  

1961 ◽  
Vol 265 (14) ◽  
pp. 686-692 ◽  
Author(s):  
Jerome P. Kassirer ◽  
William B. Schwartz

Author(s):  
E C Wirrell ◽  
L D Hamiwka ◽  
L A Hamiwka ◽  
S Grisaru ◽  
X Wei

Objective:Posterior reversible encephalopathy syndrome (PRES) occurs most commonly in the setting of known hypertension or use of immunosuppressive agents.Design and Methods:We report four previously-well children who presented acutely with altered mentation, seizures and visual disturbances and were diagnosed with PRES.Results:Only one child had a history of gross hematuria prior to the seizure. All four were discovered to be hypertensive only after onset of their neurological symptoms, and were subsequently diagnosed with glomerulonephritis. All four had rapid resolution of neurological symptoms with adequate treatment of hypertension.Conclusions:Blood pressure must be measured promptly in all children presenting with these symptoms. If elevated, the diagnosis of PRES should be strongly considered and a workup for renal disease pursued.


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