scholarly journals Effect of exercise on cognitive function in chronic disease patients: a meta-analysis and systematic review of randomized controlled trials

2017 ◽  
Vol Volume 12 ◽  
pp. 773-783 ◽  
Author(s):  
Hong Cai ◽  
Guichen Li ◽  
Shanshan Hua ◽  
Yufei Liu ◽  
Li Chen
Keyword(s):  
Systematic Review ◽  
Chronic Disease ◽  
Cognitive Function ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Chronic Disease Patients

P3-615: EFFECTS OF SOY ISOFLAVONES ON COGNITIVE FUNCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS

2006 ◽  
Vol 14 (7S_Part_25) ◽  
pp. P1365-P1366
Author(s):  
Chendi Cui ◽  
Rahel Birru ◽  
Beth E. Snitz ◽  
Masafumi Ihara ◽  
Brian J. Lopresti ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Function ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Soy Isoflavones ◽  
Controlled Trials ◽  
Randomized Controlled

scholarly journals Effects of soy isoflavones on cognitive function: a systematic review and meta-analysis of randomized controlled trials

2019 ◽  
Vol 78 (2) ◽  
pp. 134-144 ◽  
Author(s):  
Chendi Cui ◽  
Rahel L Birru ◽  
Beth E Snitz ◽  
Masafumi Ihara ◽  
Chikage Kakuta ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Function ◽  
Randomized Controlled Trials ◽  
Data Extraction ◽  
Meta Analysis ◽  
Soy Isoflavones ◽  
Cochrane Library ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Design Characteristics

Abstract Context The results of preclinical and observational studies support the beneficial effect of soy isoflavones on cognition. Objective This review aimed to evaluate the effects of soy isoflavones on cognition in adults. Data Sources The PUBMED, EMBASE, Ovid Medline, Cochrane Library, and clinicaltrials.gov databases were searched. Study Selection Two researchers independently screened 1955 records, using the PICOS criteria: participants were adults; intervention was dietary sources with soy isoflavones or isolated soy isoflavones; comparator was any comparator; outcome was cognitive function; study type was randomized controlled trials (RCTs). A third researcher was consulted to resolve any discrepancies. Sixteen RCTs were included and their quality assessed. Data Extraction Information on study design, characteristics of participants, and outcomes was extracted. PRISMA guidelines were followed. Data Analysis A random-effects meta-analysis was used to pool estimates across studies. In the 16 RCTs (1386 participants, mean age = 60 y), soy isoflavones were found to improve overall cognitive function (standardized mean difference [SMD], 0.19; 95% confidence interval [CI], 0.07–0.32) and memory (SMD, 0.15; 95%CI, 0.03–0.26). Conclusion The results showed that soy isoflavones may improve cognitive function in adults. Systematic Review Registration PROSPERO registration no. CRD42018082070.

Interventions to Reduce Alcohol Harms in Low and Middle Income Countries: a Systematic Review and Meta Analysis

2018 ◽  
Author(s):  
Joao Ricardo Nickenig Vissoci
Keyword(s):  
Systematic Review ◽  
Alcohol Use ◽  
Randomized Controlled Trials ◽  
Brain Stimulation ◽  
Meta Analysis ◽  
World Health ◽  
Controlled Trials ◽  
Middle Income ◽  
Brief Motivational Intervention ◽  
Randomized Controlled

BackgroundHarmful alcohol use leads to a large burden of disease and disability which disportionately impacts LMICs. The World Health Organization and the Lancet have issued calls for this burden to be addressed, but issues remain, primarily due to gaps in information. While a variety of interventions have been shown to be effective at reducing alcohol use in HICs, their efficacy in LMICs have yet to be assessed. This systematic review describes the current published literature on alcohol interventions in LMICs and conducts a meta analysis of clinical trials evaluating interventions to reduce alcohol use and harms in LMICs.MethodsIn accordance with PRISMA guidelines we searched the electronic databases Pubmed, EMBASE, Scopus,Web of Science, Cochrane, and Psych Info. Articles were eligible if they evaluated an intervention targeting alcohol-related harm in LMICs. After a reference and citation analysis, we conducted a quality assessment per PRISMA protocol. A meta-analysis was performed on the 39 randomized controlled trials that evaluated an alcohol-related outcome.ResultsOf the 3,801 articles from the literature search, 87 articles from 25 LMICs fit the eligibility and inclusion criteria. Of these studies, 39 randomized controlled trials were included in the meta-analysis. Nine of these studies focused specifically on medication, while the others focused on brief motivational intervention, brain stimulation, AUDIT-based brief interventions, WHO ASSIST-based interventions, group based education, basic screening and interventions, brief psychological or counseling, dyadic relapse prevention, group counseling, CBT, motivational + PTSD based interview, and health promotion/awareness. Conclusion Issues in determining feasible options specific to LMICs arise from unstandardized interventions, unequal geographic distribution of intervention implementation, and uncertain effectiveness over time. Current research shows that brain stimulation, psychotherapy, and brief motivational interviews have the potential to be effective in LMIC settings, but further feasibility testing and efforts to standardize results are necessary to accurately assess their effectiveness.

Sign in / Sign up

Export Citation Format

Share Document