Safety, tolerability, and pharmacokinetics of simotinib, a novel specific EGFR tyrosine kinase inhibitor, in patients with advanced non-small cell lung cancer: results of a phase Ib trial

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Small Cell Lung ◽

Phase Ib

Egfr-Tyrosine Kinase Inhibitor (Tki) Rechallenge with Bevacizumab in Egfr-Mutant Non-Small Cell Lung Cancer (Nsclc)

Annals of Oncology ◽

10.1093/annonc/mdu349.65 ◽

2014 ◽

Vol 25 ◽

pp. iv452

Author(s):

K. Otsuka ◽

A. Hata ◽

R. Kato ◽

J. Takeshita ◽

C. Okuda ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Small Cell Lung ◽

Egfr Mutant

Evaluation of the potential effect of dacomitinib, an EGFR tyrosine kinase inhibitor, on ECG parameters in patients with advanced non-small cell lung cancer

Investigational New Drugs ◽

10.1007/s10637-019-00887-0 ◽

2019 ◽

Vol 38 (3) ◽

pp. 874-884

Author(s):

Weiwei Tan ◽

Nagdeep Giri ◽

Susan Quinn ◽

Keith Wilner ◽

Kourosh Parivar

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Potential Effect ◽

Small Cell ◽

Small Cell Lung ◽

Spatiotemporal T790M heterogeneity in individual patients with non-small cell lung cancer (NSCLC) after acquired resistance to EGFR-tyrosine kinase inhibitor (TKI).

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.8067 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 8067-8067 ◽

Cited By ~ 1

Author(s):

Akito Hata ◽

Nobuyuki Katakami ◽

Hiroshige Yoshioka ◽

Katsuhiro Masago ◽

Shiro Fujita ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Acquired Resistance ◽

Small Cell ◽

Small Cell Lung ◽

BMS-690514, a VEGFR and EGFR tyrosine kinase inhibitor, shows anti-tumoural activity on non-small-cell lung cancer xenografts and induces sequence-dependent synergistic effect with radiation

British Journal of Cancer ◽

10.1038/sj.bjc.6605748 ◽

2010 ◽

Vol 103 (3) ◽

pp. 347-353 ◽

Cited By ~ 17

Author(s):

Y Loriot ◽

P Mordant ◽

N Dorvault ◽

T De la motte Rouge ◽

J Bourhis ◽

...

Keyword(s):

Lung Cancer ◽

Synergistic Effect ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Small Cell Lung ◽

Severe Aplastic Anemia during Osimertinib Therapy in a Patient with EGFR Tyrosine Kinase Inhibitor–Resistant Non–Small Cell Lung Cancer

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2016.12.023 ◽

2017 ◽

Vol 12 (5) ◽

pp. e46-e47 ◽

Cited By ~ 2

Author(s):

Hiroaki Ogata ◽

Yuzo Yamamoto ◽

Taishi Harada ◽

Yoichi Nakanishi ◽

Isamu Okamoto ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Aplastic Anemia ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Small Cell Lung ◽

mTORC2 contributes to the metabolic reprogramming in EGFR tyrosine-kinase inhibitor resistant cells in non-small cell lung cancer

Cancer Letters ◽

10.1016/j.canlet.2018.07.025 ◽

2018 ◽

Vol 434 ◽

pp. 152-159 ◽

Cited By ~ 4

Author(s):

Chun-Te Chiang ◽

Alexandra N. Demetriou ◽

Nolan Ung ◽

Niharika Choudhury ◽

Kimya Ghaffarian ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Metabolic Reprogramming ◽

Small Cell Lung ◽

Abstract B34: Overcoming resistance to EGFR-Tyrosine Kinase Inhibitor therapy in non-small cell lung cancer

Clinical Cancer Research ◽

10.1158/1078-0432.12aacriaslc-b34 ◽

2012 ◽

Vol 18 (3 Supplement) ◽

pp. B34-B34

Author(s):

Rafael Sierra ◽

Anderson Chang ◽

Jason Moffat ◽

Benjamin G. Neel ◽

Ming-Sound Tsao

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Small Cell Lung ◽

Tyrosine Kinase Inhibitor Therapy

Abstract 1232: Overcoming resistance to EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer

10.1158/1538-7445.am2012-1232 ◽

2012 ◽

Author(s):

J Rafael Sierra ◽

Anderson Chang ◽

Jason Moffat ◽

Benjamin G. Neel ◽

Ming-Sound Tsao

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Small Cell Lung ◽

Tyrosine Kinase Inhibitor Therapy

Treatment and prognosis after progression in long-term responders to EGFR-tyrosine kinase inhibitor in advanced non-small cell lung cancer

Archives of Medical Science ◽

10.5114/aoms.2016.57586 ◽

2016 ◽

Vol 1 ◽

pp. 107-111 ◽

Cited By ~ 2

Author(s):

Zhengbo Song ◽

Yiping Zhang

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Small Cell Lung ◽

EGFR Protein Expression in Non–Small Cell Lung Cancer Predicts Response to an EGFR Tyrosine Kinase Inhibitor—A Novel Antibody for Immunohistochemistry or AQUA Technology

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-11-0209 ◽

2011 ◽

Vol 17 (24) ◽

pp. 7796-7807 ◽

Cited By ~ 28

Author(s):

Celine Mascaux ◽

Murry W. Wynes ◽

Yasufumi Kato ◽

Cindy Tran ◽

Bernadette Reyna Asuncion ◽

...

Keyword(s):

Lung Cancer ◽

Protein Expression ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Small Cell Lung ◽