Elucidating the in vivo fate of nanocrystals using a physiologically based pharmacokinetic model: a case study with the anticancer agent SNX-2112

Constraint-based perturbation analysis with cluster Newton method: a case study of personalized parameter estimations with irinotecan whole-body physiologically based pharmacokinetic model

BMC Systems Biology ◽

10.1186/s12918-017-0513-2 ◽

2017 ◽

Vol 11 (S7) ◽

Cited By ~ 1

Author(s):

Shun Asami ◽

Daisuke Kiga ◽

Akihiko Konagaya

Keyword(s):

Newton Method ◽

Perturbation Analysis ◽

Pharmacokinetic Model ◽

Whole Body ◽

Parameter Estimations ◽

Application of a Physiologically Based Pharmacokinetic Model to Assess Propofol Hepatic and Renal Glucuronidation in Isolation: Utility of In Vitro and In Vivo Data

Drug Metabolism and Disposition ◽

10.1124/dmd.112.050294 ◽

2013 ◽

Vol 41 (4) ◽

pp. 744-753 ◽

Cited By ~ 15

Author(s):

Katherine L. Gill ◽

Michael Gertz ◽

J. Brian Houston ◽

Aleksandra Galetin

Keyword(s):

Pharmacokinetic Model ◽

Epimerization of moxalactam by albumin and simulation of in vivo epimerization by a physiologically based pharmacokinetic model

Chirality ◽

10.1002/(sici)1520-636x(1999)11:4<309::aid-chir8>3.0.co;2-g ◽

1999 ◽

Vol 11 (4) ◽

pp. 309-315 ◽

Cited By ~ 3

Author(s):

Takayoshi Yoshikawa ◽

Takayoshi Oguma ◽

Teruhisa Ichihashi ◽

Haruki Kinoshita ◽

Koichiro Hirano ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Simulation of Toluene Kinetics in the Rat by a Physiologically Based Pharmacokinetic Model with Application of Biotransformation Parameters Derived Independently in Vitro and in Vivo

Toxicological Sciences ◽

10.1093/toxsci/32.2.260 ◽

1996 ◽

Vol 32 (2) ◽

pp. 260-268

Author(s):

JOOST DEJONGH ◽

BAS J. BLAAUBOER

Keyword(s):

Pharmacokinetic Model ◽

Predicting Drug Interaction Potential With a Physiologically Based Pharmacokinetic Model: A Case Study of Telithromycin, a Time-Dependent CYP3A Inhibitor

Clinical Pharmacology & Therapeutics ◽

10.1038/clpt.2011.305 ◽

2012 ◽

Vol 91 (4) ◽

pp. 700-708 ◽

Cited By ~ 34

Author(s):

Md L T Vieira ◽

P Zhao ◽

E G Berglund ◽

K S Reynolds ◽

L Zhang ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Pharmacokinetic Model ◽

Time Dependent ◽

Physiologically Based ◽

Cyp3a Inhibitor

A physiologically based pharmacokinetic model to predict the superparamagnetic iron oxide nanoparticles (SPIONs) accumulation in vivo

nano Online ◽

10.1515/nano.0012.00072 ◽

2018 ◽

Author(s):

Adny Henrique Silva ◽

Enio Lima Jr ◽

Marcelo Vasquez Mansilla ◽

Roberto Daniel Zysler ◽

Mary Luz Mojica Pisciotti ◽

...

Keyword(s):

Iron Oxide ◽

Iron Oxide Nanoparticles ◽

Pharmacokinetic Model ◽

Superparamagnetic Iron Oxide ◽

Superparamagnetic Iron Oxide Nanoparticles ◽

Oxide Nanoparticles ◽

Development of a Physiologically Based Pharmacokinetic Model for Sinogliatin, a First-in-Class Glucokinase Activator, by Integrating Allometric Scaling, In Vitro to In Vivo Exploration and Steady-State Concentration–Mean Residence Time Methods: Mechanistic Understanding of its Pharmacokinetics

Clinical Pharmacokinetics ◽

10.1007/s40262-018-0631-z ◽

2018 ◽

Vol 57 (10) ◽

pp. 1307-1323 ◽

Cited By ~ 4

Author(s):

Ling Song ◽

Yi Zhang ◽

Ji Jiang ◽

Shuang Ren ◽

Li Chen ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Allometric Scaling ◽

Steady State Concentration ◽

Glucokinase Activator ◽

Physiologically Based ◽

State Concentration

Combining an In Vitro Kinetic Model with a Physiologically-Based Pharmacokinetic Model to Assess the Potential In Vivo Fate of Polyvinyl Pyrrolidone-Vinyl Acetate Copolymers

Pharmaceutical Research ◽

10.1007/s11095-017-2305-1 ◽

2018 ◽

Vol 35 (4) ◽

Author(s):

Daniel S. Hsieh ◽

Liang Luo ◽

Yan Xu ◽

Joshua D. Engstrom ◽

Qi Gao

Keyword(s):

Kinetic Model ◽

Vinyl Acetate ◽

Pharmacokinetic Model ◽

Polyvinyl Pyrrolidone ◽

Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed Physiologically-Based Pharmacokinetic Model of Ritonavir Norvir Tablet Absorption in Humans Under Fasted and Fed State Conditions

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.0c00043 ◽

2020 ◽

Vol 17 (7) ◽

pp. 2329-2344 ◽

Cited By ~ 4

Author(s):

Sumit Arora ◽

Amita Pansari ◽

Peter Kilford ◽

Masoud Jamei ◽

Iain Gardner ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Fed State ◽

Physiologically Based ◽

In Vivo Extrapolation

Development of a Translational Physiologically Based Pharmacokinetic Model for Antibody-Drug Conjugates: a Case Study with T-DM1

The AAPS Journal ◽

10.1208/s12248-017-0131-3 ◽

2017 ◽

Vol 19 (6) ◽

pp. 1715-1734 ◽

Cited By ~ 8

Author(s):

Antari Khot ◽

Jay Tibbitts ◽

Dan Rock ◽

Dhaval K. Shah

Keyword(s):

Pharmacokinetic Model ◽

Antibody Drug Conjugates ◽

Drug Conjugates ◽

Physiologically Based ◽

Antibody Drug