<p>Platelet-rich plasma in the management of chronic low back pain: a critical review</p>

ABSTRACT Back pain and its associated complications are of increasing importance among military members. The sacroiliac joint (SIJ) is a common source of chronic low back pain (LBP) and functional disability. Many patients suffering from chronic LBP utilize opioids to help control their symptoms. Platelet-rich plasma (PRP) has been used extensively to treat pain emanating from many different musculoskeletal origins; however, its use in the SIJ has been studied only on a limited basis. The patient in this case report presented with chronic LBP localized to the SIJ and subsequent functional disability managed with high-dose opioids. After failure of traditional treatments, she was given an ultrasound-guided PRP injection of the SIJ which drastically decreased her pain and disability and eventually allowed for complete opioid cessation. Her symptom relief continued 1 year after the injection. This case demonstrates the potential of ultrasound-guided PRP injections as a long-term treatment for chronic LBP caused by SIJ dysfunction in military service members, which can also aid in the weaning of chronic opioid use.

Download Full-text

Intra-articular Injection of Platelet-rich Plasma in the Management of Chronic Low Back Pain due to Facet Arthropathy: A Case Report with 12 Months Follow-up

Journal on Recent Advances in Pain ◽

10.5005/jp-journals-10046-0008 ◽

2015 ◽

Vol 1 (1) ◽

pp. 26-27

Author(s):

Prithwis Bhattacharyya ◽

Priyanka Dev

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Case Report ◽

Chronic Low Back Pain ◽

Platelet Rich Plasma ◽

Low Back ◽

Facet Arthropathy

Download Full-text

Pengaruh Core Stabilization Exercise Terhadap Penurunan Nyeri Chronic Low Back Pain: Critical Review

Urecol Journal. Part C: Health Sciences ◽

10.53017/ujhs.45 ◽

2021 ◽

Vol 1 (1) ◽

pp. 29-36

Author(s):

Wahyuni Wahyuni ◽

Muhammad Afif Robiatul Azis

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Chronic Low Back Pain ◽

Critical Review ◽

Low Back ◽

Stabilization Exercise ◽

Core Stabilization ◽

Core Stabilization Exercise

Latar Belakang: Low back pain (LBP) merupakan keadaan nyeri punggung bawah. Nyeri yang timbul pada low back pain bukan merupakan suatu penyakit ataupun diagnosis, melainkan istilah untuk nyeri yang dirasakan di area anatomi yang terkena dengan berbagai variasi lamanya terjadi nyeri. Pada beberapa kejadian nyeri awal dapat berlanjut selama periode 3 bulan dan akhirnya berkembang menjadi chronic low back pain (CLBP). Tujuan: Studi ini adalah untuk mengetahui pengaruh penurunan nyeri setelah diberikan core stabilization exercise (CSE) terhadap chronic low back pain berdasarkan literature yang ada dan mengetahui jenis latihan core stabilization exercise pada chronic low back pain berdasarkan literature yang ada. Metode: Penelitian ini adalah menggunakan studi critical review. Hasil: Dari hasil studi ini ditemukan 8 dari 148 artikel yang sesuai dengan kriteria inklusi. Pada studi ini 8 artikel yang digunakan sebagai landasan studi yang dilanjutkan untuk tahap appraisal. Hasil dari appraisal terdapat 6 artikel memiliki nilai Quartile 1 (Q1) dan 2 artikel yang memiliki nilai Quartile 2 (Q2). Lalu penilaian PEDro scale didaptkan 7 artikel yang memiliki bias rendah > 5 dan 1 artikel memiliki bias yang tinggi ?5. Kesimpulan: Berdasarkan hasil studi yang telah dilakukan pada pengaruh core stabilization exercise terhadap penurunan nyeri pada chronic low back pain berdasarkan studi pada literature yang ada dapat disimpulkan bahwa core stabilization exercise berpengaruh dalam penurunan nyeri pada chronic low back pain.

Download Full-text

Platelet rich plasma application in chronic low back pain – clinical and anatomical rationale and review of the literature

10.35465/27.4.2019.pp27-41 ◽

2019 ◽

pp. 27-41

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Chronic Low Back Pain ◽

Platelet Rich Plasma ◽

Autologous Blood ◽

Case Series ◽

Intervertebral Discs ◽

Biologically Active ◽

Common Symptom ◽

Low Back

Low back pain (LBP) is an extremely common symptom in populations of all ages with significant economic and social burden worldwide. As such it should be among the priorities for trying to find more efficient methods for prevention and treatment. Currently the exact cause for the complaints can be found in most of the cases following thorough clinical examination, adequate diagnostic tests and modern image diagnosis. Most often the complaints are cause by degenerative processes affecting certain structures in the lumbosacral area – the intervertebral discs, the tendons/entheses along the iliac crest, the sacroiliac and lumbar facet joints. Platelet rich plasma (PRP) is a widely used therapeutic method aimed at recovering (both anatomical and functional) degenerative or traumatic damaged collagen tissues by injecting/applying autologous blood concentrate, rich in growth factors and other biologically active molecules. PRP demonstrates huge potential in stimulating cell proliferation and metabolic activity in vitro. Trials with animals show/prove the full recovery of the structural changes and the matrix integrity of the damaged tissue. In recent years some prospective clinical studies and published case series report that PRP could be a safe and efficient therapy for patients with chronic low back pain that do not yield to traditional/standard treatment options. Data though limited/scarce for the time being includes/covers the most common cause for this complaint, namely pathology of the intervertebral discs, facet and sacroiliac joints, as well as paraspinal soft tissues. The possibility for precise intralesional application of this regeneration autologous product in the damaged tissue gives it a huge advantage over the common algorithms currently used in the clinical practice to treat patients with such complaints. Future bigger studies including image methods to evaluate the structural recovery of the degenerative changed tissue responsible/blamed for the pain and functional deficit would bring light to the place PRP therapy should take in the treatment of low back pain.

Download Full-text