scholarly journals Single nucleotide polymorphisms in the mitochondrial displacement loop and age at onset of non-Hodgkin lymphoma

2013 ◽  
pp. 1041
Author(s):  
Zhanjun Guo ◽  
Fan ◽  
Wang
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Hodgkin Lymphoma ◽  
Age At Onset ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Non Hodgkin Lymphoma

scholarly journals Single nucleotide polymorphisms in ABCB1 and CBR1 can predict toxicity to R-CHOP type regimens in patients with diffuse non-Hodgkin lymphoma

Haematologica ◽  
2015 ◽  
Vol 100 (5) ◽  
pp. e204-e206 ◽  
Author(s):  
L. P. Jordheim ◽  
V. Ribrag ◽  
H. Ghesquieres ◽  
S. Pallardy ◽  
R. Delarue ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Hodgkin Lymphoma ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Non Hodgkin Lymphoma

Analysis of interleukin-10 promoter single nucleotide polymorphisms and risk of non-Hodgkin lymphoma in a Malaysian population

2014 ◽  
Vol 56 (1) ◽  
pp. 163-168 ◽  
Author(s):  
Yat-Yuen Lim ◽  
Yoon-Ming Chin ◽  
Mei-Chee Tai ◽  
Somayeh Fani ◽  
Kian-Meng Chang ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Hodgkin Lymphoma ◽  
Interleukin 10 ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Malaysian Population ◽  
Non Hodgkin Lymphoma

scholarly journals Single-Nucleotide Polymorphisms in Genes Encoding for CC Chemokines were Not Associated with the Risk of Non-Hodgkin Lymphoma

2013 ◽  
Vol 22 (7) ◽  
pp. 1332-1335 ◽  
Author(s):  
Qiong Chen ◽  
Tongzhang Zheng ◽  
Qing Lan ◽  
Catherine Lerro ◽  
Nan Zhao ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Hodgkin Lymphoma ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Non Hodgkin Lymphoma ◽  
Genes Encoding ◽  
Cc Chemokines

scholarly journals Identification of Predictive Pathways for Non-Hodgkin Lymphoma Prognosis

2010 ◽  
Vol 9 ◽  
pp. CIN.S6315 ◽  
Author(s):  
Xuesong Han ◽  
Yang Li ◽  
Jian Huang ◽  
Yawei Zhang ◽  
Theodore Holford ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Predictive Power ◽  
B Cell Lymphoma ◽  
Separate Analysis ◽  
Nucleotide Polymorphisms ◽  
Clinical Factors ◽  
Single Nucleotide ◽  
Kegg Pathways ◽  
Non Hodgkin Lymphoma ◽  
Individual Snps

Despite decades of intensive research, NHL (non-Hodgkin lymphoma) still remains poorly understood and is largely incurable. Recent molecular studies suggest that genomic variants measured with SNPs (single nucleotide polymorphisms) in genes may have additional predictive power for NHL prognosis beyond clinical risk factors. We analyzed a genetic association study. The prognostic cohort consisted of 346 patients, among whom 138 had DLBCL (diffuse large B-cell lymphoma) and 101 had FL (follicular lymphoma). For DLBCL, we analyzed 1229 SNPs which represented 122 KEGG pathways. For FL, we analyzed 1228 SNPs which represented 122 KEGG pathways. Unlike in existing studies, we targeted at identifying pathways with significant additional predictive power beyond clinical factors. In addition, we accounted for the joint effects of multiple SNPs within pathways, whereas some existing studies drew pathway-level conclusions based on separate analysis of individual SNPs. For DLBCL, we identified four pathways, which, combined with the clinical factors, had medians of the prediction logrank statistics as 2.535, 2.220, 2.094, 2.453, and 2.512, respectively. As a comparison, the clinical factors had a median of the prediction logrank statistics around 0.552. For FL, we identified two pathways, which, combined with the clinical factors, had medians of the prediction logrank statistics as 4.320 and 3.532, respectively. As a comparison, the clinical factors had a median of the prediction logrank statistics around 1.212. For NHL overall, we identified three pathways, which, combined with the clinical factors, had medians of the prediction logrank statistics as 5.722, 5.314, and 5.441, respective. As a comparison, the clinical factors had a median of the prediction logrank statistics around 4.411. The identified pathways have sound biological bases. In addition, they are different from those identified using existing approaches. They may provide further insights into the biological mechanisms underlying the prognosis of NHL.

Single nucleotide polymorphisms in the mitochondrial displacement loop and age-at-onset of familial breast cancer

2016 ◽  
Vol 27 (5) ◽  
pp. 3082-3085 ◽  
Author(s):  
Haiping Lee ◽  
Cuizhi Geng ◽  
Meng Cheng ◽  
Zheng Lee ◽  
Zhanjun Guo
Keyword(s):  
Breast Cancer ◽  
Single Nucleotide Polymorphisms ◽  
Familial Breast Cancer ◽  
Age At Onset ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

scholarly journals SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinson's Disease

2019 ◽  
Vol 34 (9) ◽  
pp. 1333-1344 ◽  
Author(s):  
Rubén Fernández‐Santiago ◽  
Núria Martín‐Flores ◽  
Francesca Antonelli ◽  
Catalina Cerquera ◽  
Verónica Moreno ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Single Nucleotide Polymorphisms ◽  
Age At Onset ◽  
Mtor Pathway ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

scholarly journals Genome-wide linkage analysis of age at onset of alcohol dependence: a comparison between microsatellites and single-nucleotide polymorphisms

BMC Genetics ◽  
2005 ◽  
Vol 6 (Suppl 1) ◽  
pp. S12 ◽  
Author(s):  
Bamidele O Tayo ◽  
Yulan Liang ◽  
Saverio Stranges ◽  
Maurizio Trevisan
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Linkage Analysis ◽  
Alcohol Dependence ◽  
Age At Onset ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Genome Wide

Single nucleotide polymorphisms in the mitochondrial displacement loop and age-at-onset of epithelial ovarian cancer

2014 ◽  
Vol 27 (2) ◽  
pp. 1141-1143 ◽  
Author(s):  
Desheng Kong ◽  
Shuhong Shi ◽  
Yanfang Li ◽  
Rongxia Li ◽  
Min Li
Keyword(s):  
Ovarian Cancer ◽  
Single Nucleotide Polymorphisms ◽  
Epithelial Ovarian Cancer ◽  
Age At Onset ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

scholarly journals Single Nucleotide Polymorphisms Associated With Gut Homeostasis Influence Risk and Age-at-Onset of Parkinson's Disease

2020 ◽  
Vol 12 ◽  
Author(s):  
Anastazja M. Gorecki ◽  
Megan C. Bakeberg ◽  
Frances Theunissen ◽  
Jade E. Kenna ◽  
Madison E. Hoes ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Single Nucleotide Polymorphisms ◽  
Age At Onset ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Gut Homeostasis

scholarly journals Single-Nucleotide Polymorphisms in the LEPR Gene Are Associated with Divergent Phenotypes for Age at Onset of Puberty in Davisdale Ewes1

2014 ◽  
Vol 90 (2) ◽  
Author(s):  
Avijit Haldar ◽  
Michelle C. French ◽  
Rudiger Brauning ◽  
Sara J. Edwards ◽  
Anne R. O'Connell ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Age At Onset ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Lepr Gene
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